Paper Talk

723-BHB Enhances CAR T Cell Antitumor Function


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The article investigates how β-hydroxybutyrate (BHB), a ketone body produced during a ketogenic diet, enhances the effectiveness of CAR T cell therapy in treating cancer. Through various mouse models and human volunteer data, researchers demonstrated that BHB metabolically reprograms T cells by fueling the TCA cycle and increasing ATP production. This boost in energy leads to superior tumor contro...去小宇宙查看完整单集简介
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Paper TalkBy 淼淼Elva