The paper introduces X-Atlas/Pisces, the most extensive genome-wide CRISPRi Perturb-seq dataset created to date, featuring 25.6 million single-cell transcriptomes across 16 biological contexts. Leveraging this massive resource, researchers developed X-Cell, a diffusion language model designed to predict how genetic interventions reshape gene expression. The model improves accuracy by integrating m...去小宇宙查看完整单集简介
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