Anne is back with Anna, one of her first patients dealing with immune-related infertility. Anna shares her four-year journey through five miscarriages, multiple failed IVF transfers, and the medical dismissals that made her stop trusting anyone in the system. She walks through what happened when her husband's varicocele and high DNA fragmentation were finally addressed mid-IVF cycle, why her clinic created embryos before testing sperm quality, how she navigated immune treatments including LIT therapy and IVIG trips to Chicago, and why doing everything at once meant she'll never know what actually worked. Now facing secondary infertility, Anna talks about the psychological difference between trying again with proof her body can carry versus the hopelessness of repeated loss. This episode is for anyone who's been told everything looks normal but keeps losing pregnancies, anyone wondering whether to try again after finally having success, or anyone realizing that unexplained infertility just means no one has looked hard enough yet.

00:00 - Intro
02:05 - First two losses with heartbeats, no answers
04:29 - Third loss: Abnormal embryo becomes the IVF sales pitch
06:10 - Meeting Anne and starting IVF
09:15 - First retrieval results and DNA fragmentation discovery
14:37 - Why ICSI doesn't fix high fragmentation
16:16 - Varicocele repair through interventional surgery
20:32 - First transfer: Blighted ovum and retained tissue
23:04 - Fourth loss and hitting rock bottom
27:05 - Immune treatments: Intralipids and LIT therapy
32:40 - Success after immune protocol (or was it?)
36:39 - Flying to Chicago for IVIG during pregnancy
38:10 - Preterm birth at 34 weeks and lingering questions
41:06 - Secondary infertility: Going back in with a different mindset
43:38 - What Anne would do differently now
46:01 - The PCOS "miracle baby" myth explained
50:22 - What's actually accessible and what matters most
55:10 - The importance of having someone hold hope for you