Investigators are pursuing more aggressive strategies to maintain sinus rhythm. One area of current inquiry for certain arrhythmias centers on pulmonary vein isolation as an alternative to atrioventricular node ablation with biventricular pacing. How effective is pulmonary vein isolation for preventing an arrhythmia relapse? Dr. Mohammed Khan, an electrophysiologist at Cardiovascular Associates in Elk Grove Village, Illinois, joins host Dr. Doug Weaver to explain which of your patients may be optimal candidates for pulmonary vein isolation.