Trying to Conceive with Dr. Sasha Hakman

A Reproductive Endocrinologist's Guide to Protecting Your Hormones


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In this solo episode, Dr. Sasha goes deep on one of her most-requested topics: endocrine disrupting chemicals (EDCs). What they are, where they're hiding, how they affect your hormones and fertility, and exactly what you can do about it.

As a reproductive endocrinologist and infertility specialist, she brings both clinical expertise and personal practice to this conversation. This episode is grounded in evidence-based research, including a 136-page scientific statement from the Endocrine Society, and is designed to inform, not alarm.

In This Episode, You'll Learn:

  • What the endocrine system is and why hormones are the body's "keys and locks"

  • The definition of EDCs and why exposure is considered a global public health crisis

  • Why even tiny exposures can have outsized health impacts (it's not always dose-dependent)

  • The major classes of EDCs to know: BPA/bisphenols, phthalates, PFAS (forever chemicals), parabens, glyphosate, heavy metals, and triclosan and where each one hides

  • The 4 mechanisms EDCs use to disrupt your hormones - including epigenetic modification that can be passed down through generations

  • Why in utero exposure is the most critical window, and what effects have been linked to fetal EDC exposure (including hypospadias, cryptorchidism, diminished egg reserve, and premature ovarian insufficiency)

  • How EDC exposure impacts puberty, fertility, and the TTC window specifically - including the finding that phthalate metabolites were detected in the follicular fluid of 99% of women undergoing egg retrieval

  • The link between EDC exposure and sperm count decline (down 50% in 50 years, per Dr. Shanna Swan's research)

  • Health risks in adulthood: endometriosis, PCOS/PEMOS, diminished ovarian reserve, thyroid dysfunction, breast cancer, prostate cancer, and more

  • The Tier 1 vs. Tier 2 framework for prioritizing what to eliminate first

  • Why "BPA-free" is a marketing gimmick and what to look for instead

  • Why "unscented" ≠ fragrance-free - and what that means for your products

  • Why fragrance is banned entirely in IVF embryology labs (and what that tells us)

  • A study showing BPA urinary levels drop significantly after just 3 days of cutting out heated plastic

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    Trying to Conceive with Dr. Sasha HakmanBy Dr Sasha Hakman