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In this episode, I talk with Dr. Sing-Yi Feng, a Pediatric Emergency Medicine physician and Toxicologist, about ingestions of acetaminophen and ibuprofen, and general guidelines for evaluation of ingestions. We discuss important knowledge points for diagnosis, management, and continuation of care for our patients at home, in the inpatient unit, and in the critical care setting. Although Dr. Feng is a pediatrician first, she reviews care for patients of all ages, as ibuprofen and acetaminophen are among the most common ingestions of people at any age.