In this episode, Chris Myers chats with Mr. Luke Jones, an experienced orthopedic surgeon specializing in knee injuries. The focus of our discussion is ACL injuries, particularly in female athletes. This topic gained significant attention during the World Cup when numerous elite female footballers suffered from ACL ruptures. We delve into the anatomy of the ACL, its crucial role in knee stability, and why it's a common site of injury in sports. The conversation highlights the higher incidence of ACL injuries in female athletes compared to their male counterparts. We explore various factors contributing to this disparity, including anatomical, hormonal, and neuromuscular differences. The podcast also addresses the multifactorial nature of ACL injuries, discussing both intrinsic and extrinsic risk factors. We touch upon the importance of understanding these factors for effective prevention and treatment. The discussion extends to the impact of ACL injuries on athletes' careers, especially in elite sports, and the decision-making process around surgery. Furthermore, we examine prevention strategies, including training modifications and the implementation of specific warm-up routines like the FIFA 11+. The conversation also covers the effectiveness of ACL reconstruction surgeries and the differences in outcomes between male and female athletes.