The Egg Factor

Advancing the Accuracy of Ovulation Trigger Timing for Highly Individualized Oocyte Retrieval (HIER)


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It has been more than 40 years since the first IVF baby was born and today, millions of babies are born using assisted reproductive technology. Throughout the years, new studies and research have been conducted which contributes to the advancement of reproductive medicine. One topic that has become popular is the process of how follicle development is monitored and how to determine the timing of the egg retrieval. 

HIER is based on the understanding that follicle maturity is a biological process, not just a measurement. Instead of treating all patients with the same protocol, the process of HIER tailors the timing of the ovulation trigger and egg retrieval to the individual patient. 

Our founder, Dr. Norbert Gleicher, reported the first successful transvaginal egg retrieval in human history, helping to shape the future of IVF as we know it today. CHR is known for tackling some of the most challenging fertility cases—especially women over 40 and those with diminished ovarian reserve—by offering highly individualized, evidence-based care when others often turn patients away.

Our team has published more than 450 peer-reviewed research papers advancing reproductive medicine, reflecting our deep commitment not only to patient care but to the science that drives better outcomes. At CHR, you're never just a number. You're part of a community focused on giving you the personalized support, science, and hope you deserve.

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The Egg FactorBy Center For Human Reproduction