The swampy, cypress-covered Francis Marion National Forest was once an escape route for a controversial figure in America's fight for independence.

Each year, mushers drive a pack of 16 dogs through the rough wilderness between Anchorage and Nome in honor of a famous Alaska medical emergency.

To prepare for an 90-mile, 8-week research trip across Alaska, apprentices in Juneau's Icefield Research Program must first learn how to survive in the wild.

Where the first American mafias, Louis Armstrong, and chef Emeril Lagasse started out, New Orleans remains the soul of Louisiana.

Just a quaint summer home for the Vanderbilt family, The Biltmore Estate and its grounds are as stunning from the air as they are from the ground.

Started by mobsters and ruled by Wall Street, the Las Vegas strip has become the capitol of extravagance...and bad behavior.

In 1828, John Jacob Astor built a trading post on the Missouri River. Business was so profitable that it only took four decades for Astor to become America's first multimillionaire.

As a precocious 3-year-old in small-town Mississippi, Oprah Winfrey learned how to entertain an audience when she was encouraged to recite bible passages to her church.

Surrounded by four of America's Great Lakes, Michigan has more freshwater shoreline than any other state. Each of its shores has its own unique landscape, from forests, to beaches, to giant walls of sand.

In 1942, one thousand families were pushed out of Oak Ridge, Tennessee as part of The Manhattan Project - the US government's top secret initiative to engineer an atomic bomb.