AHEAD OF THE CURVE: Cystic Fibrosis

Leading experts address the current evidence-based best practices, with educational and inspirational sessions on adherence, originally presented at the 29th North American Cystic Fibrosis Conference.

Hear from Francis Collins, Tsui Lap-Chee, and Jack Riordan whose labs worked together to discover the CF gene. CF luminaries Bob Beall, Pamela Davis, Philip M. Farrell and others share how the discovery of the CF gene changed everything. Faculty present the clinical data and how patient care is evolving.

Meet Daniel, a three-year-old whose routine throat culture just grew P. aeruginosa, originally presented at the 28th North American Cystic Fibrosis Conference.

Originally presented at the 2013 North American Cystic Fibrosis Conference, this program covers differentiation of CF classes and current/potential therapies and using the CFTR2 database.

Learn about the 5 classes of CFTR mutations, the latest research on emerging therapies for each mutation class and follow four individuals with CF. These case-based modules were presented at the 36th European Cystic Fibrosis Society Conference in Lisbon, Portugal.

This program examines state-of-the-art strategies for assessment of early lung disease in patients with CF. It reviews the importance of early intervention and optimal strategies to prevent airway obstruction in patients with CF

This program describes the correlation between a patient’s CFTR genotype and their CF phenotype, explains the importance of genetic testing in suspected adult-onset CF, and identifies the practical uses of the CFTR2 database.

In this podcast guest author Dr. Margaret Rosenfeld from the University of Washington School of Medicine, discusses the rationale for early Pseudomonas aeruginosa eradication, Identifies the inhaled and oral antibiotics that have been compared in clinical trials for early Pseudomonas eradication, and describes the potential adverse effects of early Pseudomonas eradication therapy.

Case studies offer opportunity to differentiate the needs of each patient when managing respiratory infections. Dr. Elliott Dasenbrook will review the prevalence of important CF organisms over the last 10 years, the impact of respiratory tract MRSA on survival, the association between a virulent strain of P. aeruginosa that can spread among patients and lung transplant or death, as well as the impact of chronic non-tuberculous Mycobacterial lung disease on lung function.

In this podcast guest author Amanda Radmer Leonard, Pediatric Nutrition Practitioner, of the Johns Hopkins Children’s

Center, describes approaches to the treatment of low vitamin D levels in patients with cystic fibrosis, discuss the variability of fecal elastase result during the first year of life, and summarizes the importance of tailoring nutritional interventions to specific patient and family situations.