Artificial intelligence is rapidly reshaping the future of health care — from predictive early warning systems that detect patient deterioration to ambient AI tools that streamline clinical documentation. In this Leadership Dialogue conversation, Marc Boom, M.D., president and CEO of Houston Methodist and the 2026 AHA board chair, speaks with Amy Rockman, director of the Artificial Intelligence Center of Excellence, a systemwide initiative of Rutgers Health and RWJBarnabas Health. The two explore AI applications that are delivering measurable improvements in hospital mortality, safety, and clinician burnout, and how a “living lab” approach, interdisciplinary teams, and responsible AI integration are benefitting patients and the health care workforce.