Explore how AI and technology can support anxiety management and emotional wellness, without replacing human therapy. In this episode, John Cordray, LPC, breaks down the evidence-based mental wellness tools helping professionals manage anxiety, shares which anxiety coping strategies work best with AI assistance, and reveals where technology falls short. Perfect for overthinkers seeking practical mental health solutions, cognitive techniques, and burnout.

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Host, John Cordray, LPC www.johncordraylpc.com

Sources:

Benefits & Advances

• Sohn et al. (2026) — Systematic review and meta-analysis of chatbots in the management of depressive and anxiety symptoms. npj Digital Medicine. Published March 2026. DOI: 10.1038/s41746-026-02566-w. This covers the Hedges’ g effect sizes (0.31 for depression, 0.28 for anxiety) across nearly 7,400 participants.
• Feng et al. (2025) — The Effectiveness of AI Chatbots in Alleviating Mental Distress and Promoting Health Behaviors Among Adolescents and Young Adults: Systematic Review and Meta-Analysis. Journal of Medical Internet Research, 27:e79850 (2025). DOI: 10.2196/79850. This includes the standard mean differences for anxiety (-0.37), stress (-0.41), and psychosomatic symptoms (-0.48).
• Heinz et al. (2025) — Randomized Trial of a Generative AI Chatbot for Mental Health Treatment (Therabot). NEJM AI (2025). This is the first RCT showing clinically significant reductions in MDD, GAD, and related symptoms, with therapeutic alliance ratings comparable to human therapists.
• Cachia et al. (2025) — AI for Proactive Mental Health: A Multi-Institutional, Longitudinal, Randomized Controlled Trial (Flourish app). Harvard University working paper / arXiv preprint (2025). This covers improvements in positive affect, resilience, belonging, and protective effects against stress.
• OpenAI & MIT Media Lab (2025) — Studies on affective use and emotional well-being with ChatGPT (including voice mode). These show mixed effects on loneliness, with voice interactions sometimes reducing it at moderate use but increasing isolation with heavy daily reliance.
• Wysa-related studies (multiple, including 2025 updates) — Various trials showing reductions in depression and anxiety symptoms (e.g., up to 22% in some cohorts) with CBT/mindfulness integration.
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Limitations & Dangers

• Stanford University studies (2025) — Multiple papers and reports on AI mental health tools, including risks of stigma, crisis mishandling, parasocial bonds, and inappropriate responses. Key examples include work on LLM safety in therapy contexts and Common Sense Media collaboration with Stanford’s Brainstorm Lab.
• Frontiers in Psychiatry (2025) — Reviews noting that while chatbots are feasible and acceptable short-term, evidence for long-term safety and efficacy (especially in moderate-to-severe cases) remains limited.
• Character.AI-related tragedies (2024–2026) — Lawsuits and settlements involving families alleging harm from companion-style chatbots (including role-play scenarios leading to isolation or escalation). Google/Character.AI reached settlements in early 2026 with multiple families. Similar patterns noted in lawsuits against other platforms involving crisis responses.
• American Psychological Association (APA) advisory (late 2025) — Caution on generative AI chatbots and wellness apps for mental health, citing insufficient evidence and regulation for safety in emotional support or crisis situations.

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From John Cordray, LPC – Creator of MyndStill app

@JohnCordrayLPC on X/LinkedIn

Informational support only—not a substitute for professional therapy.

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