Endo in a Bite

Algorithm for Management of Dyslipidemia - 2025 AACE Update (Part 5)


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This episode reviews the evaluation of adults with severe hypertriglyceridemia, according to the 2025 AACE Algorithm.

• Severe Hypertriglyceridemia: Understand impaired triglyceride clearance, chylomicron accumulation, and increased pancreatitis risk, including multifactorial causes.

• Familial Chylomicronemia Syndrome: Recognize this rare, early onset disorder with persistent hypertriglyceridemia despite low fat intake.

• Dysbetalipoproteinemia (APOE E2/E2): Learn about equal elevations of TG and cholesterol, tuberous xanthomas, low Apo B, and excellent response to fibrates.

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Endo in a BiteBy Sumbul Beg, MD