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AlphaGenome is an AI model that predicts the effects of genetic variants with high resolution. It analyzes 1 Mb DNA sequences to simultaneously model gene expression, splicing, and accessibility. It outperforms specialized models, enabling more accurate interpretation of clinical variants.
https://doi.org/10.1038/s41586-025-10014-0
By Edel Perez-LopezAlphaGenome is an AI model that predicts the effects of genetic variants with high resolution. It analyzes 1 Mb DNA sequences to simultaneously model gene expression, splicing, and accessibility. It outperforms specialized models, enabling more accurate interpretation of clinical variants.
https://doi.org/10.1038/s41586-025-10014-0