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A family tragedy became a company that helps people understand their own bodies.
Florence Iwegbue was 28 when the call came that her mother had fallen into a coma. Years later, her own son had his first seizure, and she refused to bury a child. So she dropped everything and went looking for answers. What she built is LiveWello, a personal health platform that helps you talk to your DNA.
In this episode, Florence breaks down nutrigenomics and pharmacogenomics in plain English: why the same medication, meal or workout can work for one person and fail for another, and what your genetics can tell you about it. She shares the ancestral diet she credits for her own turnaround, the health battles she went through herself, and the tiny daily habits that keep her moving through perimenopause, fatigue and depression.
You'll learn:
Why personalised health starts with knowing your genetics, not guessing.
How diet and movement can look different when they follow your ancestry.
How to build a habit from the smallest possible step (she started by putting on workout clothes for 30 days).
What Gene Chat is and how you can ask your DNA why you can't sleep.
TIMESTAMPS
0:00 The seizure that changed everything
0:36 Meet Florence Iwegbue and LiveWello
1:32 Who Florence was before LiveWello
3:01 The call about her mother and the hardest decision
5:21 What LiveWello is and why she built it
8:54 How the platform turns your DNA into a personal plan
11:28 Yams, potatoes and why food is ancestral
14:49 The village trip: women living longer and looking better
15:15 Ugu and the 70% sub-Saharan diet
17:57 Her own health battles: fatigue, fibroids and depression
21:02 Running, weight gain and the cortisol gene
22:10 Meditation, breathwork and rebuilding her mornings
24:15 Baby steps: how to build a habit you actually keep
26:00 Gene Chat: ask your DNA anything
27:47 Privacy, anonymity and the data debate
28:15 Running LiveWello with her husband and the menopause hospital project
30:04 Building health tech at 50 as an African woman
31:15 Recognition, the BBC and Forbes, and why she doesn't hold on to it
32:45 Raising a son with autism and training like a sprinter
34:23 Where LiveWello is headed
35:04 If you're in your hardest chapter right now
36:40 Final thoughts
ABOUT FLORENCE IWEGBUE
Florence is the co-founder and lead of LiveWello, a personal health platform that blends genetic data, wellness and heritage-based practices. LiveWello won a Health Unity Award at Stanford for its use of generative AI in life sciences, and Florence has been featured by the BBC, ABC News and Forbes.
DISCLAIMER
This conversation is for information and inspiration only. It is not medical advice. Speak to your doctor or healthcare professional before changing your medication, diet or exercise.
#LiveWello #Genetics #WomensHealth #Longevity #Perimenopause #AlwaysOffTheRecord
CONNECT WITH FLORENCE IWEGBUE
Instagram: @livwello
Website: www.livewello.com
Companies mentioned in this episode:
The longest conversation you'll ever have is the one with yourself — and it shapes every other conversation you have.
This week on Always Off The Record, we sit down with Amira Mansour, a London-based communication coach, speaker, and founder of The Communication Expert. After a decade in corporate learning and development across finance and asset management, Amira now helps hundreds of professionals — and brands like Nike, Adidas, and giffgaff — find their voice and stop over-explaining, shrinking, or staying silent to keep the peace.
We get into why "talking" isn't the same as "communicating," how to actually navigate hard conversations without avoiding them, the real cost of choosing politeness over honesty, and why your inner dialogue is quietly running the show in every room you walk into.
In this episode, we cover:
Key Quote:
"The longest, most important conversation you're ever going to have in your life is the one with yourself."
Connect with Amira:
Follow Always Off The Record:
Is AI Quietly Replacing Real Human Connection? 🤖💔
We're not just using AI anymore — we're forming relationships with it. In this episode, we dig into how artificial intelligence is reshaping identity, relationships, and reality itself, and why the line between human and machine is getting dangerously blurry.
From AI companionship and synthetic relationships to the looming loneliness epidemic, we unpack what happens when technology moves faster than our ability to think critically about it. We also call out a hard truth: our education system still isn't teaching the next generation how to navigate an AI-saturated world — and that gap is costing us more than we realize.
If you've ever wondered whether your online interactions are still "real," whether critical thinking is dying out, or what it actually means to be human in an AI-driven future — this conversation is for you.
In this episode:
This isn't just a conversation about technology — it's a conversation about what we stand to lose, and what we need to protect, as AI reshapes reality as we know it.
🔔 Subscribe for more honest conversations on AI, identity, relationships, and the future of human connection.
💬 Drop a comment: do you think you could tell the difference between a real connection and an artificial one?
#ArtificialIntelligence #AIRelationships #HumanConnection #LonelinessEpidemic #CriticalThinking #FutureOfAI #DigitalIdentity #TechAndSociety #AIvsHuman #SyntheticRelationships
Takeaways:
The principal focus of this podcast episode is the exploration of ambition, identity, and the dynamics of building a significant career, particularly for women navigating traditionally male-dominated spaces. We engage in a profound dialogue with Ashumi Sanghvi, a distinguished entrepreneur and founder of Future Plus, who articulates the importance of continuous learning and the cultivation of human relationships in achieving success. Ashumi shares her personal journey, reflecting on the challenges and triumphs she has encountered as an "insider-outsider" within various cultural contexts. Throughout our conversation, we delve into the necessity for women to assert their presence and the impact of community support in fostering empowerment. Ultimately, this episode serves as a call to action for listeners to embrace their curiosity and invest in the relationships that will propel their aspirations forward.
Takeaways:
Companies mentioned in this episode:
Divorce and separation are complex processes that demand careful navigation and preparation. The salient point of our discussion revolves around the necessity of securing competent legal counsel at the onset of contemplating a divorce or separation. We emphasize that engaging with multiple lawyers to ascertain their strategies and compatibility is paramount, as this step can substantially influence the outcome of one's case. Furthermore, we delve into the emotional toll that such transitions impose, acknowledging the societal pressures and personal shame that often accompany the dissolution of relationships. Throughout the episode, we stress the importance of maintaining civility, particularly when children are involved, and the need to prioritize one's own well-being in the face of significant life changes. The dialogue navigates the complex terrain of relationship dissolution, offering listeners a wealth of insights into the legal, emotional, and practical considerations that accompany divorce and separation. The speakers emphasize the critical importance of engaging knowledgeable legal counsel early in the process. They advocate for individuals to conduct thorough research and interviews with multiple attorneys to ensure they receive competent representation. This preparatory step is presented as essential for understanding one’s rights and potential outcomes, thereby enabling individuals to make informed decisions as they navigate the often convoluted landscape of family law. In addition to legal considerations, the speakers delve into the profound emotional impact of divorce, acknowledging that the dissolution of a relationship can evoke feelings of shame, inadequacy, and loneliness. They encourage listeners to challenge societal stigmas surrounding divorce and to be open about their struggles, reinforcing the idea that seeking support is not a sign of weakness but a necessary step towards healing. This candid exploration of emotional vulnerability serves to destigmatize the experience of divorce, fostering a greater sense of community among those who may feel isolated in their struggles. In conclusion, this episode serves as both a pragmatic guide and an empathetic exploration of the divorce process. It underscores the need for thorough preparation and emotional resilience, urging listeners to take proactive steps in securing their legal rights while also fostering supportive relationships. By blending practical advice with heartfelt discussion, the speakers aim to equip their audience with the tools necessary to navigate the complexities of divorce with confidence and grace.
Takeaways:
The prevailing inquiry addressed in this discourse revolves around the question of whether individuals are engaging in romantic pursuits with the explicit intention of matrimony. I assert, with conviction, that contemporary statistics demonstrate a marked decline in marriage rates, accompanied by a notable absence of cohabitation among younger demographics. This episode endeavors to explore the paradigms of dating, juxtaposing historical perspectives with present-day practices, thereby revealing a significant evolution in societal norms surrounding intimate relationships. We delve into the myriad terminologies that have emerged in the modern dating lexicon, elucidating their implications and the behaviors they describe. As we navigate through the complexities of dating today, we invite listeners to reflect upon their own experiences and the shifting dynamics of romantic interactions in an increasingly digital age. Dating in contemporary society presents a stark contrast to its historical antecedents, as articulated by the speakers in this engaging discourse. They delve into the notion of whether individuals are dating with the intent to marry, concluding that, contrary to traditional expectations, many are not. Statistical evidence is marshaled to support the assertion that cohabitation rates are declining and that even among younger generations, there exists a notable absence of physical intimacy, a phenomenon intriguingly tied to the emergence of new social dynamics and cultural shifts. The speakers reflect on their personal experiences of dating in previous decades, characterized by distinct social norms and expectations. They reminisce about the more rigid codes of conduct that governed early romantic interactions, including awkward first kisses and the limitations placed on physical affection. This nostalgia contrasts sharply with the current landscape where, they suggest, the rules have become more ambiguous, leading to potentially superficial connections devoid of genuine intent. The discussion progresses to address the modern dating scene’s complexities, including the prevalence of casual encounters and the implications of dating apps, which have fundamentally altered interpersonal dynamics. A critical theme emerges regarding the psychological mechanisms underlying contemporary dating behavior. The speakers explore the phenomenon of emotional detachment in modern relationships, highlighting the prevalence of gaslighting and love bombing as tactics employed by individuals seeking validation rather than authentic connection. Through this lens, they present a compelling argument that many individuals engage in dating not for commitment but for ego reinforcement. The episode culminates in a call for a deeper understanding of the motivations behind dating behaviors, urging listeners to reflect on their own experiences and the emotional ramifications of the dating culture that pervades today’s society. The discourse navigates the intricate terrain of modern dating, with the speakers expressing a keen interest in dissecting the current state of romantic relationships. They inquire about the intentions underlying contemporary dating practices, positing that many individuals are no longer pursuing relationships with marriage as a goal. This assertion is substantiated by a review of statistical trends indicating decreasing marriage rates and a shift towards non-traditional relationship structures, wherein physical intimacy is sometimes altogether absent. The speakers juxtapose their own past experiences with the present dating landscape, reminiscing about the structured and often conservative nature of courtship in previous generations. They reflect on the societal norms that once dictated romantic interactions, such as the necessity of parental approval and the gradual progression of physical intimacy. This nostalgic exploration serves as a backdrop against which they critique the current dating paradigm, which they argue has become increasingly ambiguous and, at times, disingenuous. A significant portion of the conversation is dedicated to examining the psychological underpinnings of dating behaviors today, particularly the prevalence of gaslighting and emotional manipulation. The speakers assert that many individuals engage in dating as a means of fulfilling psychological needs rather than forming genuine connections. They advocate for a more profound comprehension of these dynamics, encouraging listeners to consider the emotional toll of navigating a dating culture rife with superficiality and insincerity. The episode concludes with a call to action, urging individuals to cultivate awareness of their dating experiences and the underlying motivations that drive their interactions.
Takeaways:
Adversity is an inevitable aspect of the human experience, yet it is our response to such challenges that ultimately defines our paths. In this discourse, we explore the paramount significance of cultivating a resilient mindset when confronted with setbacks. We emphasize the critical necessity of reframing our internal narratives, specifically urging listeners to eschew the detrimental cycle of self-deprecation that often accompanies failure. By adopting a perspective that prioritizes learning and growth, we assert that individuals can transcend their difficulties and emerge stronger. Through a series of personal anecdotes and practical strategies, we elucidate how one might navigate the tumultuous waters of adversity, fostering resilience and a renewed sense of agency in the process.
The conversation articulated in this episode presents a profound examination of adversity, a commonality shared by all individuals throughout their lives. The speakers delve into the essence of how one engages with adversity, positing that it is not the adversity itself that defines us, but rather the manner in which we respond to it. This pivotal distinction is explored through the lens of psychological resilience and the cultivation of a growth-oriented mindset. The speakers assert that overcoming adversity necessitates a conscious effort to learn from setbacks, thereby transforming potential failures into invaluable lessons that propel us forward. Central to their discourse is the theme of self-reflection and personal accountability. The speakers encourage listeners to introspectively assess their boundaries and self-respect, particularly in the context of interpersonal relationships. By challenging individuals to articulate what constitutes unacceptable behavior, the conversation seeks to empower listeners to reclaim their agency and foster healthier dynamics in their lives. The speakers also underscore the value of perspective, illustrating how a shift in our narrative can significantly alter our emotional responses to adversity. As the dialogue unfolds, it becomes evident that adversity, while often perceived as a stumbling block, can also serve as a catalyst for profound personal growth and transformation. The speakers remind us that each challenge we face carries with it the potential for insight and development, urging listeners to embrace the discomfort of adversity as a necessary aspect of the human experience. Through actionable strategies and a commitment to self-discovery, we can learn to navigate the complexities of life with resilience and grace.
Takeaways:
In this episode of Off the Record, your favorite girlfriends Amanda and Madi dive deep into what it really means to live intentionally – and why drifting through life on autopilot is no longer an option. From toxic friendships to flaky partners and careers that don’t fit, they unpack how your daily choices quietly shape your future.
Amanda shares how she curates her friendships, career and environment around her core values, while Madi opens up about years of “letting life happen” and what finally forced her to start planning with purpose. They talk about 5‑year (and 2.5‑year) plans, why lateness is a values issue not just “a bad habit,” and how indecision is often the worst decision of all.
You’ll hear:
If you’ve ever stayed with the wrong partner, tolerated disrespectful friends, or felt like life is just “happening” to you, this conversation is your wake‑up call. Grab your notebook – by the end of this episode, you’ll have practical tools to set boundaries, clean up your circle, and start living on purpose, not by accident.
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