The Andrea Yates case is often remembered only for its horror, but the medical reality behind it has been largely misunderstood. In this episode of The Murder Mindset, we examine what actually happens inside a brain in the midst of postpartum psychosis, one of the rarest and most severe psychiatric emergencies in perinatal mental health. We break down how hormone crashes, chronic sleep deprivation, and abrupt medication changes can destabilize neural networks; how years of documented warning signs, delusions, deterioration, hospitalizations, and inconsistent treatment revealed a brain in crisis long before the tragedy; and how systemic gaps in psychiatric care left Andrea dangerously unsupported. This episode does not excuse violence; it explains it through neuroscience, psychology, and the failures of the systems meant to protect families. Because if we don’t understand these patterns, we can’t prevent them. Follow @themurdermindset on Instagram and TikTok, and listen on Apple, Spotify, YouTube, and anywhere you get your podcasts.

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