ANGPTL4 continues to generate broad clinical interest this week, with new mechanistic data in diabetic retinopathy, acute lung injury, and hepatocellular carcinoma; no new adipose-targeted RNA delivery papers appeared in the 7-day window.

Six new studies reinforce ANGPTL4 as a multi-tissue regulator with relevance to lipid metabolism, diabetic complications, and emerging therapeutic strategies; no adipose-targeted RNA delivery papers appeared in the past 7 days.

ANGPTL4 expanded its footprint in diabetic complications this week — strong mechanistic data implicating it in proliferative diabetic retinopathy and a new review on its role in diabetic nephropathy — alongside cancer angiogenesis, lung-injury cytoprotection, and head-and-neck SCC prognosis. No new adipose-targeted RNA delivery papers (siRNA/ASO/LNP/GalNAc) appeared in the lookback window.