The New World screwworm (NWS) is forecast to reach the United States later this year. Eradicated from the country in 1966, this flesh-eating parasitic fly affects all warm-blooded mammals and animals, has the potential to cause massive harm to the livestock industry, and would cost millions, potentially billions, of dollars to eradicate again. Animal owners throughout the southern U.S. are urged to stay vigilant to identify potential cases. In this episode, Dr. Sally Denotta, UF Veterinary Medicine equine medicine specialist, and Dr. Ted Burgess, UF/IFAS veterinary entomologist, discuss the NWS, what to look for in identifying a screwworm infection and who to call if they suspect their animals or livestock may be affected.