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Antibody mRNAs don't require nuclear localisation to mediate protein translation, but can be translated directly into target proteins or immunogenic activation of the immune response in vivo by using genetic sequence of the virus. It is obvious that using antibody RNA instead of viral antigen to activate the specific immune response is much safer and free from the risk of infection, which explains why antibody mRNA drugs such as mRNA vaccines are now a hot and mainstream research area.
By Echo HanAntibody mRNAs don't require nuclear localisation to mediate protein translation, but can be translated directly into target proteins or immunogenic activation of the immune response in vivo by using genetic sequence of the virus. It is obvious that using antibody RNA instead of viral antigen to activate the specific immune response is much safer and free from the risk of infection, which explains why antibody mRNA drugs such as mRNA vaccines are now a hot and mainstream research area.