In this monolog, Casey discusses a 2024 article about the increase in health and lifespan in mammals after IL-11 inhibition.

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources: Inhibition of IL-11 signalling extends mammalian healthspan and lifespan | Nature

In this monolog, Vijay discusses the difference in immune system development in term and pre-term babies.

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YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources: https://pubmed.ncbi.nlm.nih.gov/30142345/

In this monolog, Akshat ponders about the spatiotemporal underpinnings of cytokine concentrations in tissue niches...and how it all appears to function like a gossip network.

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YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw

Send us your queries/questions/suggestions at [email protected].

Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources:

Collectivist Model: https://www.nature.com/articles/s43018-020-0038-2

Rapid Switching Model: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4562415/

Competitive Model: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8126146/

Leaky Synapses: https://www.nature.com/articles/nri3242

In this episode, Akshat outlines the salient features of CAR or TCR-engineered T cells, and deigns to ponder: is one modality just objectively better than the other?

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YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw

Send us your queries/questions/suggestions at [email protected].

Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

In this Monolog, Casey discusses the unique case of a hyper-vaccinated individual in Germany with more than 200 COVID-19 vaccines and how his immunological profile looks like.

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YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources:

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(24)00134-8/fulltext

In this Monolog, Akshat discusses how the liver "speaks" both immunity and metabolism via bile to control hepatic tumors. Liver X Receptors also make an appearance.

Check out our memes on Facebook (@antibuddies), Twitter (@antibuddiesP), and Instagram (@AntibuddiesPodcast).

YouTube channel: https://www.youtube.com/channel/UCxyrHotyyY3sSwcp1zigeCw

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources:

https://www.science.org/doi/10.1126/science.aan5931

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6433546/

In the 29th episode of our Immunology 101 series, Ash and Tanu start the new year 2024 with a discussion on Barrier Immunity with a focus on the gut.

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Sources:

Kuby Immunology

In this monologue, Akshat talks about sterile inflammation, or leucocyte activation in the absence of inflammatory responses. These carefully regulated "internal affairs" of the immune system can be pathological or protective.

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

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In this monolog, Casey talks about a 2023 article from the National Institute of Biological Sciences (Beijing, China) about the role of cytokines and immune cells in sleep deprivation-induced mortality.

Source: Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals - PubMed (nih.gov)

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

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In this monolog, Vijay talks about a 2016 article from Rockefeller University about the complex crosstalk in the gut between the neurons and macrophages.

Source: Neuro-immune Interactions Drive Tissue Programming in Intestinal Macrophages - PubMed (nih.gov)

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Website: Antibuddies – Science Communication & Immunology (Antibuddies.org)

Send us your queries/questions/suggestions at [email protected].