ASCB's Pathways Podcast

ASCB's Pathways Podcast

By American Society for Cell BiologyScienceLife Sciences
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ASCB's Pathways Podcast episodes

  • Cell Bio 2022

    Check out the latest (and final) Pathways Podcast featuring graduate students Landon Savoy of  Iowa State University and Kaitlin Alemany of the University of Colorado Anschutz Medical Campus, who attended #cellio2022

    10 min
  • OpenCell Reveals the Intracellular Life of Proteins

    Manuel Leonetti, group leader in Quantitative Cell Science at the Chan Zuckerberg Biohub in San Francisco, is taking the description of “proteins in the wild” a step further with his project called OpenCell.  Through advanced imaging techniques, machine learning, artificial intelligence, data science, and software engineering, OpenCell is able to measure the quantity and track the position of different proteins in human embryonic kidney cells through time and space. So far, Leonetti says, his group has mapped 1,310 different proteins, which might sound like a lot, but this represents just 7% of the human genome. Visit https://opencell.czbiohub.org/ to learn more. 

    28 min
  • How was MBoC's Preprints Highlights system developed?

    Join Mike Lacy, the Curation Manager for Molecular Biology of the Cell journal's Preprint Highlights, and two of MBoC's Early Career Editors for a discussion on how the Preprint Highlights system of article evaluation was developed. Read more in this blog post from Mike: https://www.ascb.org/society-news/introducing-mboc-preprint-highlights/ or visit the journal website curation page here: https://www.molbiolcell.org/curation-tools

    42 min
  • Expansion Microscopy with Paul Tillberg

    Paul Tillberg, now a Janelia Fellow at the Howard Hughes Medical Institute Janelia Research Campus, developed the protocol for expansion microscopy with colleagues Ed Boyden, currently a professor at MIT, and Fei Chen, currently a Core Institute Member at the Broad Institute. The method exploits the fact that biological tissue is mostly water, and it is this watery fraction, Tillberg explains, that is replaced by a “swellable hydrogel” that expands the sample to sizes that make it much easier to image with familiar fluorescent tags and standard light microscopy equipment.

    44 min

About ASCB's Pathways Podcast

From the publisher's feed

Pathways Podcast is produced by the American Society for Cell Biology (ASCB) and features news and interviews for anyone interested in the life sciences.