In this episode, Drs. Scott Marshall from Pfizer, Sandra Visser from Merck, and Amy Cheung from AstraZeneca discuss “Good Practices in Model-Informed Drug Discovery and Development: Practice, Application, and Documentation”: their White Paper published in the March 2016 issue of PSP. You can get free access the White Paper by clicking here.

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This episode features Daniel Hertz of the University of Michigan College of Pharmacy discussing pharmacogenetics and its potential role in screening and treating patients. Read his commentary from the February 2016 issue on Precision Medicine here.

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In this episode, Peter Bonate from Astellas, discusses effective communication in systems pharmacology and pharmacometric models. You can read a review of Dr. Bonate’s book Be a Model Communicator and Sell Your Models to Anyone, reviewed by Ellen Leinfuss in the May 2015 issue, by clicking here.

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This episode features Sandra Visser and Anne Chain from Merck & Co/MSD, discussing existing practice and modeling approaches and some thoughts with regard to future directions for modeling to assess and predict cardiovascular liabilities of new drugs. You can read Dr. Visser’s Review “Implementation of Quantitative and Systems Pharmacology in Large Pharma” by clicking here.

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This episode features Aaron S. Kesselheim of the Division of Pharmacoepidemiology and Pharmacoeconomics at Brigham and Women’s Hospital discussing the 21st Century Cures Act. Read his commentary in CPT here.

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This episode features Lutz Harnisch from Clinical Pharmacology Pharmacometrics at Pfizer, discussing the Drug Disease Model Resources (DDMoRe) consortium. His Perspective article that introduces the activities of the DDMoRe consortium can also be found here.

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This episode features Michelle Roth-Cline, ‎Pediatric Ethicist in the Office of Pediatric Therapeutics at the FDA, discussing her Commentary “Microdosing Studies in Children: A US Regulatory Perspective” which published in the September 2016 issue of CPT. Read the commentary here.

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This episode features Mark A. Ware of McGill University discussing perspectives, challenges, and opportunities related to medical education on cannabis and cannabinoids. Read the article here.

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In this episode, we interview Dr. Shiew-Mei Huang, Deputy Director, Office of Clinical Pharmacology, Center for Drug Evaluation and Research at the Food and Drug Administration about a drug interaction database–a tool for evaluating the impact of renal or hepatic impairment in a pharmacologic inhibition on the systemic exposure of drugs. Read the article here. An Editorial describing the new Database article type can also be found here.

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In this episode, we interview Dr. Steven E. Kern, Deputy Director of Quantitative Sciences at the Bill and Melinda Gates Foundation, about infectious diseases in context of the possibilities for pharmacometrics and systems pharmacology to contribute to improve treatments in the area. You can view PSP’s Infectious Diseases virtual issue online to view the most recently published articles related to this field by clicking here.

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