After 54 years, the Assad's brutal reign in Syria is over. Bashar al-Assad fled to Russia with his family as rebel forces swept into the capital of Damascus. President Biden called the fall of the Assad regime a "moment of historic opportunity." But he also warned of the potential risks. And President-elect Trump gave his first network TV interview since winning the election.

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Today's episode of Up First was edited by James Hider, Andrew Sussman, Roberta Rampton, HJ Mai and Alice Woelfle. It was produced by Ziad Buchh, Nia Dumas and Kaity Kline. We get engineering support from Stacey Abbott and our technical director is Carleigh Strange.

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