Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning a major change in how we name and frame polycystic ovary syndrome, pregnancy as a window into lifelong cardiovascular risk, and a cluster of practical papers in gynecologic oncology and delivery-room decision making. Let's dive in.

This week's papers:

1. From polycystic ovary syndrome to polyendocrine metabolic ovarian syndrome: what obstetricians and gynecologists need to know. — American Journal of Obstetrics & Gynecology 2026
2. PMOS beyond the reproductive years: menopause and long-term health outcomes. — Fertility and Sterility 2026
3. Cardiovascular disease in pregnancy: physiology, global burden, risk stratification, and opportunities in care. — The Lancet 2026
4. Adverse pregnancy outcomes and long-term cardiovascular disease risk. — The Lancet 2026
5. Episiotomy and Anal Sphincter Injury During Operative Vaginal Delivery in a U.S. Cohort. — Obstetrics & Gynecology 2026
6. Minimally invasive surgery without a uterine manipulator versus open radical hysterectomy for early-stage cervical cancer: A retrospective propensity-score-matched single-center cohort study. — Gynecologic Oncology 2026
7. Molecular groups predict response to fertility-sparing treatment of endometrial carcinoma: a systematic review and metanalysis. — Gynecologic Oncology 2026
8. Incidence, survival, and symptoms at recurrence among vulvar cancer patients treated with curative intent: a population-based cohort study. — American Journal of Obstetrics & Gynecology 2026
9. Management of Multiple Sclerosis During Pregnancy and the Reproductive Years in 2026: An Expert Clinical Review. — American Journal of Obstetrics & Gynecology 2026
10. A Practical Management Approach to Vulvar Dermatoses and Genitourinary Syndrome of Menopause. — Obstetrics & Gynecology 2026

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Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning first-trimester prediction and risk stratification in high-risk obstetrics, how we interpret the evidence base in gestational diabetes, and a cluster of papers reshaping midlife and gynecologic care, from menopausal cardiovascular risk to the molecular subtyping of fibroids and endometrial cancer…

This week's papers:

1. Isthmin-2 is a first-trimester predictor of preeclampsia and fetal growth restriction. — Nature Medicine 2026
2. Intra-amniotic Categories of Preterm Prelabor Rupture of Membranes: Gestational Age-Specific Distribution, Amniotic fluid Microbial Profiles, and Neonatal Outcomes. — American Journal of Obstetrics & Gynecology 2026
3. Pre-Procedure Predictors of Six-Month Survival After Fetoscopic Laser Ablation for Twin-Twin Transfusion Syndrome (TTTS): Retrospective Observational Study. — BJOG 2026
4. Neonatal outcomes in gestational diabetes trials: What clinicians should consider when interpreting treatment effects. — American Journal of Obstetrics & Gynecology 2026
5. The Cardiometabolic Effects of Menopause. — Obstetrics & Gynecology 2026
6. A perspective on the revised American College of Obstetricians and Gynecologists' guidance for transvaginal ultrasound in the evaluation of postmenopausal bleeding. — Menopause 2026
7. Combined Oral Contraception. — Obstetrics & Gynecology 2026
8. Clinical Trajectories and MRI-Based Triage of Uterine Leiomyoma Molecular Subtypes: A Large-Scale Retrospective Analysis of 720 Genotyped Tumors. — American Journal of Obstetrics & Gynecology 2026
9. Molecular characterization of NSMP endometrial cancer and its relevance for treatment. — Gynecologic Oncology 2026
10. A Uterus-Preserving Laparoscopic Technique for Cervicovaginal Agenesis With Functional Uterine Remnants. — BJOG 2026

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Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning cervical cerclage and labour induction on the obstetric side, recurrent pregnancy loss and fertility treatment on the reproductive side, and gynaecologic disease phenotyping, cancer disparities, and new practice policy. Let's dive in.

This week's papers:

1. Obstetric Cerclage — Obstetrics & Gynecology 2026
2. Salpingectomy for the Prevention of Epithelial Ovarian Cancer — Obstetrics & Gynecology 2026
3. Vaginal Misoprostol Compared to Vaginal Dinoprostone for Induction of Labour: A Systematic Review and Meta-Analysis — BJOG 2026
4. A double-blind multi-centre randomised placebo-controlled trial of doxycycline in women with recurrent miscarriage and chronic endometritis defined by CD138 positive stromal cells — Human Reproduction 2026
5. Endometrial preparation with vs without ovulation for frozen-embryo transfer: systematic review and meta-analysis of randomized controlled trials — Ultrasound in Obstetrics & Gynecology 2026
6. High Versus Low Transvaginal Cerclage and Pregnancy Outcomes: A Secondary Analysis of the C-STICH Trial — BJOG 2026
7. Updated Federal Regulation: The Pregnant Workers Fairness Act (PWFA) — Obstetrics & Gynecology 2026
8. Endometriosis risk factors and comorbidities by endometriosis lesion macrophenotypes: An analysis from the What is Endometriosis (WisE) study — American Journal of Obstetrics & Gynecology 2026
9. Endocrine disease and pregnancy loss - a nationwide cohort study — Fertility and Sterility 2026
10. Trends in U.S. Gynecologic Cancers (2001-2019): Influence of Social Determinants, Geographic Disparities, and Specialist Access on Stage at Diagnosis — American Journal of Obstetrics & Gynecology 2026

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Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning prenatal screening and intrapartum fetal surveillance, menopause and long-term cardiometabolic risk, and gynecologic surgery, imaging, and reproductive medicine. Let's dive in.

This week's papers:

1. A Prospective, Multi-Site Study of Performance of Cell-Free DNA Testing for Recessive Conditions in a Large, General-Risk Pregnancy Population — Obstetrics & Gynecology 2026
2. Clinical and histological chorioamnionitis, particularly when associated with funisitis, attenuate intrapartum fetal heart rate responses and increase vulnerability to hypoxic-ischemic brain injury at milder degrees of acidemia — American Journal of Obstetrics & Gynecology 2026
3. The role of metabolic and bariatric surgery for obesity management in endometrial intraepithelial neoplasia and endometrial cancer: an SGO and SAGES clinical practice statement — Gynecologic Oncology 2026
4. Long-Term Effects of Pelvic Floor Muscle Training Combined With Electrical Stimulation Biofeedback Among Women With Symptomatic Pelvic Organ Prolapse: A Randomised Controlled Trial — BJOG 2026
5. Cost-Effectiveness Analysis of Menopausal Hormone Therapy — Obstetrics & Gynecology 2026
6. Menopausal Estrogen Therapy and Risk of Breast Cancer — Obstetrics & Gynecology 2026
7. Long-term risk of cardiovascular disease after assisted reproductive technology and infertility: A cohort study — PLOS Medicine 2026
8. Diagnostic accuracy of transvaginal ultrasound for adenomyosis using consensus-based direct and indirect sonographic signs: prospective cohort study — Ultrasound in Obstetrics & Gynecology 2026
9. Quality of life outcomes after sentinel lymph node biopsy in patients with early-stage cervical cancer: Results from the prospective multicentre SENTIX study — Gynecologic Oncology 2026
10. Modified natural cycle versus hormone replacement therapy embryo transfer in women over 40 years old: a retrospective analysis — Fertility and Sterility 2026

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Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning maternal mortality and postpartum consequences, the strengths and limits of obstetric ultrasound and Doppler, menopause care in complex patients, and reproductive medicine and gynecologic surgery. Let's dive in.

This week's papers:

1. Trends in Pregnancy-Related Mortality in the United States: Pregnancy Mortality Surveillance System, 2005-2024 — Obstetrics & Gynecology 2026
2. Menopause Management in Patients With Cancer — Obstetrics & Gynecology 2026
3. Integrative Medicine Approaches for Menopause — Obstetrics & Gynecology 2026
4. What does uterine artery Doppler reflect in late pregnancy? Insights from angiogenic, hemodynamic, and vascular markers in preeclampsia — American Journal of Obstetrics & Gynecology 2026
5. Head-to-head prospective comparison of diagnostic accuracy of preoperative ultrasonography and MRI in patients undergoing surgery for deep endometriosis using #Enzian classification — Ultrasound in Obstetrics & Gynecology 2026
6. Association between leading follicle size and clinical pregnancy in gonadotropin-stimulated intrauterine insemination cycles with human chorionic gonadotropin trigger — Fertility and Sterility 2026
7. Association Between Blood Transfusion for Postpartum Haemorrhage and the Risk of Premature Ovarian Failure: A Nationwide Population-Based Cohort Study — BJOG 2026
8. Association Between Opioid Use Disorder and Hysterectomy Outcomes — Obstetrics & Gynecology 2026
9. Autologous platelet-rich plasma on endometrial growth and reproductive outcomes in women with thin endometrium: a multicentre cohort study — Fertility and Sterility 2026
10. Interobserver and intraobserver variability of fetal and maternal Doppler measurements: systematic review and meta-analysis — Ultrasound in Obstetrics & Gynecology 2026

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Welcome to This Week in Obstetrics and Gynecology. This week we're covering 10 notable papers spanning perinatal medicine and maternal-fetal risk stratification, maternal mental health and substance use, reproductive endocrinology and fertility outcomes, and a practical surgical question about opioid prescribing. Let's dive in.

This week's papers:

1. Evaluating Routine Opioid Compared With Nonopioid Prescribing After Laparoscopic Hysterectomy: A Randomized Controlled Trial — Obstetrics and Gynecology 2026
2. Antenatal magnesium sulfate prior to very preterm birth in routine care is associated with increased survival without cerebral palsy — American Journal of Obstetrics and Gynecology 2026
3. Recurrent implantation failure: a committee opinion — Fertility and Sterility 2026
4. Cumulative probability of a live birth after up to six sequential single euploid embryo transfers — Fertility and Sterility 2026
5. Maternal 6-valent group B Streptococcus vaccine in non-pregnant and pregnant females: a randomized phase 1/2 trial — Nature Medicine 2026
6. Antidepressant Continuation in Pregnancy and Postpartum Depression Risk Across Racial and Ethnic Groups — American Journal of Obstetrics and Gynecology 2026
7. Abnormal serum sFlt-1 and PlGF as markers of occult placental dysfunction and fetal risk in pregestational diabetes — American Journal of Obstetrics and Gynecology 2026
8. Pregnancy-Associated Drug Overdose Mortality in the United States, 2018-2023 — Obstetrics and Gynecology 2026
9. Increased risk of congenital anomalies after fertility treatment is partially mediated by multiple birth: a population-based cohort study — Human Reproduction 2026
10. Premature menopause is associated with the development of high blood pressure: a UK Biobank cohort study — Menopause 2026

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Welcome to This Week in Obstetrics & Gynecology. This week we're covering 10 notable papers spanning urogynecology, surgical management and oncology, and reproductive endocrinology and maternal health. Let's dive in.

This week's papers:

1. Vaginal Estrogen Application Techniques for Prevention of Urinary Tract Infection: A Randomized Trial — Obstetrics and gynecology 2026
2. Repeat Diagnostic and Therapeutic Procedures After Excisional Procedures for High-Grade Cervical Intraepithelial Neoplasia — Obstetrics and gynecology 2026
3. Influence of Cardiometabolic Status on Cardiovascular Effects of Oral Menopausal Hormone Therapy — Obstetrics and gynecology 2026
4. Adverse outcome in Cesarean scar pregnancy continuing into mid-to-late gestation: systematic review and meta-analysis — Ultrasound in obstetrics & gynecology 2026
5. Safety and Effectiveness of an In Situ-Forming Hydrogel Barrier in Preventing Intrauterine Adhesions After Adhesiogenic Hysteroscopic Procedures: A Multicenter, Randomized, Controlled Trial — Fertility and sterility 2026
6. Thyroid Function Throughout Pregnancy in Women With Subclinical Hypothyroidism or Hypothyroxinemia — Obstetrics and gynecology 2026
7. Initiation and Duration of Systemic Hormone Therapy for Menopausal Symptoms — Obstetrics and gynecology 2026
8. Liquid Biopsy Cell-free RNA-based Machine Learning Enables Preoperative Risk-Stratification of Uterine Leiomyosarcoma — American journal of obstetrics and gynecology 2026
9. Depressive Symptoms and Associated Factors Among Obstetrics and Gynecology First-Year Residents — American journal of obstetrics and gynecology 2026

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Welcome to This Week in Obstetrics & Gynecology. This week we're covering 10 notable papers spanning postpartum cardiovascular risk and obstetric management, safety and stratification in gynecologic oncology, and strategies for improving preventive care and patient partnerships. Let's dive in.

This week's papers:

1. Human Immunodeficiency Virus Screening and Preexposure Prophylaxis. — Obstetrics and gynecology 2026
2. Partnering With Doulas in Clinical Settings. — Obstetrics and gynecology 2026
3. Association of Hormone Therapy with Long-Term Outcomes After Chemoradiation for Locally Advanced Cervical Cancer. — American journal of obstetrics and gynecology 2026
4. Clinical utility of sentinel lymph node biopsy in atypical endometrial hyperplasia: A multicenter cohort study. — Gynecologic oncology 2026
5. Long-term neurodevelopmental outcomes after vacuum-assisted delivery: A population-based cohort study. — PLoS medicine 2026
6. Hypertension at 5 months postpartum in women with gestational diabetes. — Ultrasound in obstetrics & gynecology 2026
7. Rethinking Placenta Accreta Spectrum: A Topography-Based Framework for Prenatal Imaging and Individualized Surgery. — American journal of obstetrics and gynecology 2026
8. Barriers to cervical cancer screening and experiences using mailed at-home HPV self-collection kits among US and foreign-born Hispanic women in a safety net health system. — Gynecologic oncology 2026
9. Failure to rescue after major gynecologic cancer surgery: A National Surgical Quality Improvement Program analysis. — Gynecologic oncology 2026

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Welcome to This Week in Obstetrics & Gynecology. This week we're covering 10 notable papers spanning critical developments in maternal-fetal medicine, advances in gynecologic surgery and imaging, and new insights in reproductive endocrinology. Let's dive in.

This week's papers:

1. Ischemic Placental Disease and Hospitalization for Neurological and Psychiatric Disorders. — American Journal of Obstetrics and Gynecology 2026
2. Risk of Intra-Amniotic Infection After Cervical Ripening Balloon for Prelabor Rupture of Membranes: A Systematic Review and Meta-analysis. — Obstetrics and Gynecology 2026
3. Long-Term Outcomes After Native Tissue Hysteropexy Compared With Hysterectomy for Treatment of Pelvic Organ Prolapse. — Obstetrics and Gynecology 2026
4. Designation of small for gestational age according to seven fetal growth charts in England's National Health Service: population based cohort study of 3.2 million births. — BMJ 2026
5. Association of Glucagon-Like Peptide-1 Receptor Agonists With Menstrual Events in Reproductive-Aged Patients. — Obstetrics and Gynecology 2026
6. Prospective external validation of ADNEX and RMI for estimating risk of malignancy in adnexal masses in general gynecological settings: Danish multicenter study. — Ultrasound in Obstetrics & Gynecology 2026
7. Predicting bladder-to-uterine adhesions in patients undergoing hysterectomy using sliding-bladder sign technique with preoperative ultrasound: a diagnostic accuracy study. — Ultrasound in Obstetrics & Gynecology 2026
8. Effect of blastocyst-stage versus cleavage-stage strategy on cumulative live birth rate in assisted reproductive technology: a systematic review and meta-analysis. — Fertility and Sterility 2026
9. Progestogen-primed ovarian stimulation vs GnRH antagonists and/or agonists for women undergoing assisted reproduction: systematic review and meta-analysis. — Ultrasound in Obstetrics & Gynecology 2026
10. Endogenous progesterone guided timing of natural cycle frozen embryo transfer and reproductive outcomes in a large multicenter cohort in the United States. — Fertility and Sterility 2026

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Welcome to This Week in Obstetrics & Gynecology. This week we're covering 9 notable papers spanning prenatal interventions and advanced screening, modern approaches to labor management and reproductive safety, and long-term therapeutic outcomes in gynecologic oncology and urogynecology. Let's dive in.

This week's papers:

1. Neonatal Survival After Serial Amnioinfusions for Anhydramnios Due to Fetal Kidney Failure: The RAFT Clinical Trial. — JAMA 2026
2. Glucagon-Like Peptide-1 Receptor Agonists and Risk of Adverse Maternal Pregnancy Outcomes: A Systematic Review and Meta-analysis. — Obstetrics and Gynecology 2026
3. Long-Term Outcomes After Retropubic and Transobturator Sling Procedures: Reoperation for Recurrent Stress Urinary Incontinence. — BJOG 2026
4. Adjunctive sodium-glucose cotransporter 2 (SGLT2) inhibitors with progestins and endometrial cancer risk in benign uterine diseases and hyperplasia. — Gynecologic Oncology 2026
5. First Trimester Screening for Preterm Preeclampsia in the United Kingdom: A Cost-Effectiveness Analysis. — BJOG 2026
6. Impact of a Structured Caesarean Reduction Strategy on Perinatal Outcomes: A Retrospective Ecological Time-Trend Study. — BJOG 2026
7. From fetal life to adulthood: cardiometabolic health of offspring conceived by assisted reproductive technologies, a systematic review. — Fertility and Sterility 2026
8. Updated patient-reported outcomes and the effect of disease progression on health-related quality of life in the PRIMA/ENGOT-OV26/GOG-3012 trial of niraparib first-line maintenance therapy in patients with newly diagnosed advanced ovarian cancer. — Gynecologic Oncology 2026
9. How to apply the DAZE technique: structured approach to fetal cardiac image optimization. — Ultrasound in Obstetrics & Gynecology 2026

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