Welcome to This Week in Ophthalmology. This week we're covering 9 notable papers spanning key advancements in retinal disease management, corneal and ocular surface health, and new predictive models for optic nerve pathology. Let's dive in.

This week's papers:

1. Cryo-electron microscopy structures of human cone visual pigments. — Science 2026
2. Rose Bengal Electromagnetic Activation With Green Light for Infection Reduction: Follow-Up of a Randomized Clinical Trial. — JAMA Ophthalmology 2026
3. Neuroretinal Layer Thinning on OCT Imaging and Hemoglobin A1c in Youth With Type 1 Diabetes. — JAMA Ophthalmology 2026
4. Corneal Epithelial Alterations Associated With CDK4/6 Inhibitor Therapy in Hormone Receptor-Positive Breast Cancer. — American Journal of Ophthalmology 2026
5. Estimation of high myopia-associated optic neuropathies: the Two-Continent Eye Study. — The British Journal of Ophthalmology 2026
6. Dopamine-Enhancing Therapies and Risk of Neovascular AMD Conversion: A Target Trial Emulation. — American Journal of Ophthalmology 2026
7. Association between statin use and dry eye disease: A systematic review and meta-analysis. — American Journal of Ophthalmology 2026
8. Therapeutic response to anti-VEGF retreatment among eyes with stabilized vision after being lost to follow-up in diabetic macular edema: A nationwide, registry-based cohort study. — American Journal of Ophthalmology 2026
9. Cataract Surgery and the Risk of Conversion from Dry to Neovascular Age-related Macular Degeneration in the IRIS Registry. — Ophthalmology 2026

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Welcome to This Week in Ophthalmology. This week we're covering 9 notable papers spanning advances in retina, new evidence in cornea and anterior segment care, and insights into myopia and ophthalmic research methods. Let's dive in.

This week's papers:

1. Stereotactic radiotherapy for neovascular age related macular degeneration: year 3 and 4 extended follow up results of a randomised, double masked, sham controlled, device trial (STAR). — BMJ (Clinical research ed.) 2026
2. Antifungal Therapy for Fusarium Keratitis: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. — Cornea 2026
3. OCT-Based Quantitative Comparison of Full-Thickness Healing of Corneal Incisions in Cataract Surgery Between Diabetic and Nondiabetic Patients. — Cornea 2026
4. Real-World Insights on Switching Aflibercept Dosage for Enhanced Outcomes in Retinal Vein Occlusion (RISE-RVO): visual, anatomical and durability outcomes. — The British journal of ophthalmology 2026
5. Glaucoma in UK Biobank: A Comparison of Diagnostic- Versus Treatment-based Definitions. — Ophthalmology 2026
6. SEARCHING FOR NEW GENES THAT CAUSE USHER SYNDROME. — American journal of ophthalmology 2026
7. PROSTACYCLIN ANALOGS AND DIABETIC RETINOPATHY OUTCOMES IN PATIENTS WITH PULMONARY HYPERTENSION : A Cohort Analysis. — Retina (Philadelphia, Pa.) 2026
8. Can switching between different types of myopia control spectacles enhance effectiveness? Findings from a real-world study. — The British journal of ophthalmology 2026
9. Descemet Stripping Only in Fuchs Endothelial Corneal Dystrophy: Results of a Randomized Clinical Trial of Topical Ripasudil and Directions for Future Innovation. — American journal of ophthalmology 2026

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Welcome to This Week in Ophthalmology. This week we're covering 9 notable papers spanning new therapeutic approaches in retina, refinements in managing uveitis, and how new technology is changing risk stratification and diagnosis. Let's dive in.

This week's papers:

1. Subretinal Gene Therapy for X-Linked Retinoschisis. — The New England journal of medicine 2026
2. Polygenic risk impacts lifetime risk and prognosis of glaucoma. — Ophthalmology 2026
3. Quantitative Swept-Source Optical Coherence Tomography Angiography Indicators of Neurovascular Dysfunction in Alzheimer Disease. — JAMA ophthalmology 2026
4. 12-month outcomes of photobiomodulation in dry age-related macular degeneration: a prospective multicentre randomised double-masked controlled clinical trial. — The British journal of ophthalmology 2026
5. Anti-Adalimumab Antibodies in Patients with Inflammatory Ocular Diseases: Incidence and Clinical Outcomes. — American journal of ophthalmology 2026
6. Diabetic Retinopathy Outcomes Among Unhoused Individuals: A Big Data Analysis. — Retina (Philadelphia, Pa.) 2026
7. Evaluating reasoning in multimodal large language models for ophthalmology: a bilingual benchmark study using clinical vignettes and imaging. — The British journal of ophthalmology 2026
8. Herpesvirus Retinitis by Immune Status: Clinical Phenotypes and Predictors of Retinal Detachment and Severe Visual Impairment. — Ophthalmology. Retina 2026
9. Development of diagnostic criteria for Behçet's uveitis in a Chinese population. — The British journal of ophthalmology 2026

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Welcome to This Week in Ophthalmology. This week we're covering 9 notable papers spanning the expanding role of artificial intelligence in diagnostics, new strategies in glaucoma risk assessment, and evolving therapeutics for the anterior and posterior segment. Let's dive in.

This week's papers:

1. AI-based oculomics for trajectory-driven risk stratification of pathologic myopia in paediatric high myopia. — The British journal of ophthalmology 2026
2. Gildeuretinol Acetate vs Placebo for Geographic Atrophy Secondary to Age-Related Macular Degeneration: The SAGA Randomized Clinical Trial. — Ophthalmology. Retina 2026
3. Risk-Stratified Monitoring of Open Angle Glaucoma Suspects Based on Diagnostic Conversion Risk. — American journal of ophthalmology 2026
4. Large Language Model Authorship in Ophthalmic Publications. — Ophthalmology 2026
5. An Eye Bank and Ex Vivo Pilot Study of Shelf-Stable Corneal Plugs for Perforation Repair. — Cornea 2026
6. Smartphone-Based Proactive Self-Screening for Ocular Surface Malignancies: A Nonrandomized Clinical Trial. — JAMA ophthalmology 2026
7. Very Preterm Infant Retinal Microanatomy at 36 Weeks' Postmenstrual Age and 2-Year Neurodevelopment. — JAMA ophthalmology 2026
8. RANKL Inhibition and the Risk of Ocular Hypertension and Primary Open-Angle Glaucoma. — Investigative ophthalmology & visual science 2026
9. Stromal Transplantation and corneal-sparing techniques in ectatic diseases. — Progress in retinal and eye research 2026

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Welcome to This Week in Ophthalmology. This week we're covering nine notable papers spanning the management of chronic retinal disease, new insights in cataract and cornea, and innovative approaches to diagnostics and future therapies. Let's dive in.

This week's papers:

1. Real-World Outcomes after Switch to Aflibercept 8 mg in Neovascular AMD: Twelve Months Follow-up on 654 Eyes. — Retina (Philadelphia, Pa.) 2026
2. Disorganization of inner retinal layers and disruption of outer retinal layers as predictors of anti-vascular endothelial growth factor treatment outcomes in diabetic macular edema: A scoping review. — Survey of ophthalmology 2026
3. Pathologic Myopia Globe Shape and Long-Term Prognosis. — JAMA ophthalmology 2026
4. Evidence and Consensus Based Guidelines in Vogt-Koyanagi-Harada Disease. Multimodal imaging in Uveitis (MUV) Taskforce Report 16. — Ophthalmology. Retina 2026
5. Accuracy of 8 modern intraocular lens power calculation formulas in Asian eyes with axial length ≥ 32.00 mm. — American journal of ophthalmology 2026
6. Genetic Prediction of Keratoplasty in Fuchs Endothelial Corneal Dystrophy. — Ophthalmology 2026
7. Cost Analysis of an Outpatient MRI Pathway for Optic Disc Edema: A Time-Driven Activity-Based Costing Approach. — American journal of ophthalmology 2026
8. A Clinically Relevant Threshold of Impaired Contrast Sensitivity Among Older US Adults. — JAMA ophthalmology 2026
9. Coordinated regulation using small-molecule drugs enables controlled therapeutic genome editing and enhanced genomic precision in situ. — Science translational medicine 2026

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Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning the intersection of systemic disease and the eye, new insights in pediatric ophthalmology, and updates in both anterior and posterior segment disease management. Let's dive in.

This week's papers:

1. Global Consensus on Keratoconus and Ectatic Diseases-Edition 2. — Cornea 2026
2. Diabetic retinal disease cure accelerator: Modernizing staging and endpoints. — Progress in retinal and eye research 2026
3. When Dry Eye Is Pain: Frequency and Characteristics of a Pain Phenotype. — Ophthalmology 2026
4. Semaglutide-associated risk of nonarteritic anterior ischemic optic neuropathy in patients with type 2 diabetes: A systematic review and meta-analysis of observational studies. — PLoS medicine 2026
5. Diagnostic Accuracy of a Retinal Birefringence Scanning Device Compared With a Traditional Autorefraction Device. — JAMA ophthalmology 2026
6. Prevalence of Strabismus and Decreased Stereopsis in Parents of Children with Strabismus. — Ophthalmology 2026
7. Amniotic Membrane in Ophthalmology: Historical Perspectives, Biological Properties, and Clinical Applications. — Progress in retinal and eye research 2026
8. Early Optic Nerve Head Swelling Rate is Associated with Worsening of Visual Outcomes in Nonarteritic Anterior Ischemic Optic Neuropathy. — Ophthalmology 2026
9. Association of Atopic Dermatitis with Retinal Detachment and Postoperative Proliferative Vitreoretinopathy Risk. — Ophthalmology. Retina 2026
10. Postacute sequelae of SARS-CoV-2 infection on ophthalmic diseases: a binational cohort study. — The British journal of ophthalmology 2026

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Welcome to This Week in Ophthalmology. This week we're covering 10 notable papers spanning major advances in glaucoma surgery, the expanding role of artificial intelligence in diagnostics, and new guidance on several pressing clinical challenges. Let's dive in.

This week's papers:

1. Outcomes of minimally invasive glaucoma surgery, trabeculectomy, and tube shunt surgery in secondary glaucoma: IRIS® Registry analysis. — American journal of ophthalmology 2026
2. Analysis of choroidal OCT intensity and profile changes in high myopia: correlation with visual impairment and identification of pathological myopia. — The British journal of ophthalmology 2026
3. Multimodal artificial intelligence in retinopathy of prematurity: A comprehensive narrative review. — Survey of ophthalmology 2026
4. Intravitreal Bevacizumab Improves Trabeculectomy Survival at 3 Years: Long-term Follow-up from The 'Bevacizumab in Trabeculectomy Study'. — Ophthalmology 2026
5. Improving Efficiency in Geographic Atrophy Clinical Trials Using Run-In Phases or Single-Arm Designs. — JAMA ophthalmology 2026
6. Generative Artificial Intelligence-Driven Voice Assistance for Patient Education in Ophthalmology. — JAMA ophthalmology 2026
7. Small Copy Number Neutral Intrachromosomal Translocation of PAX6 and Aniridia. — JAMA ophthalmology 2026
8. Glucagon-Like Peptide-1 Receptor Agonists and the Risk of Non-Arteritic Anterior Ischemic Optic Neuropathy: A Consensus Statement by the North American Neuro-Ophthalmology Society and the American Academy of Ophthalmology. — Ophthalmology 2026
9. Suspending vascular endothelial growth factor inhibitors in eyes with retinal vein occlusion. — The British journal of ophthalmology 2026
10. Peripheral retinal haemorrhage density on ultra-widefield imaging as a novel biomarker for predicting diabetic retinopathy progression: a 2-year longitudinal study in Asians. — The British journal of ophthalmology 2026

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