The Retina Channel Podcast

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration


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Dr. Brian Ballios uses his expertise to talk about the article titled "Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration" by Mandai et al. The article reports use of induced pluripotent stems to culture and transplant Retinal Pigment Epithelial Cells in a patient with advanced Age-Related Macular Degeneration.

The full reference to the article:

Autologous Induced Stem-Cell–Derived Retinal Cells for Macular Degeneration, Mandai M, Watanabe A, Kurimoto Y, Hirami Y, Morinaga C, Daimon T, Fujihara M, Akimaru H, Sakai N, Shibata Y, Terada M, Nomiya Y, Tanishima S, Nakamura M, Kamao H, Sugita S, Onishi A, Ito T, Fujita K, Kawamata S, Go MJ, Shinohara C, Hata KI, Sawada M, Yamamoto M, Ohta S, Ohara Y, Yoshida K, Kuwahara J, Kitano Y, Amano N, Umekage M, Kitaoka F, Tanaka A, Okada C, Takasu N, Ogawa S, Yamanaka S, Takahashi M., N Engl J Med. 2017 Mar 16;376(11):1038-1046.

doi: 10.1056/NEJMoa1608368.

I would appreciate all comments and suggestions: [email protected]

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The Retina Channel PodcastBy Keyvan Koushan, MD, FRCSC

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