How are advanced practice providers (APPs) helping to elevate cardiovascular care? In this episode of BackTable Cardiology, Dr. Sameh Sayfo, an interventional cardiologist at Baylor Scott & White in Dallas, interviews nurse practitioner Hallie McNew about her journey from bedside ICU nursing to leading roles in cardiac surgery and structural heart practice. They discuss the unique strengths APPs bring to cardiology teams, differences between NPs and PAs, and highlight how prior nursing experience, mentorship, and structured onboarding can elevate quality of care, efficiency, and communication for cardiac patients.

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https://www.backtable.com/app

---

Timestamps
00:00 - Introduction
06:54 - APP as a Communication Bridge
10:34 - Training New Cardiology APPs
15:12 - Day In Structural Surgery Role
17:55 - Learning Imaging And EKG Skills
21:44 - Conferences and Continuing Education
27:59 - Building APP Communities And Programs
33:52 - Outpatient Hybrid Models And Hiring
39:11 - Billing Value and Patient Trust
42:03 - Handling Difficult Patient Conversations
47:27 - Wrap Up and Credits

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More about this episode
The conversation also covers best practices for orienting and mentoring new APPs, APP-led services, and the importance of learning to interpret primary data such as CT, ECHO, and EKG results. McNew shares insights on continuing education resources, including ACC subspecialty training, Mayo Clinic courses, and national meetings, plus strategies for building strong APP communities, optimizing staffing and billing models, and ways physicians and APPs can build patient trust. They also address the value of physician-APP partnerships, flexible scheduling, and the keys to creating true continuity from the hospital to the outpatient setting.

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Resources

VIVA Conference
https://viva-foundation.org/

CRT Conference
https://crtmeeting.org/

TCT Conference
https://www.tctconference.com/

Dr. Sameh Sayfo
https://www.bswhealth.com/physician/sameh-sayfo

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.
► https://www.backtable.com/app

Will new PE guidelines redefine risk and therapy in pulmonary embolism (PE) care? In this episode of the BackTable podcast, host Dr. Michael Barraza is joined by interventional cardiologist Dr. Jay Giri and emergency physician Dr. Trevor Cummings to break down the latest changes in PE management. They discuss how multidisciplinary pulmonary embolism response teams (PERT) are implementing these guidelines at their institutions, the introduction of a more nuanced A-E risk stratification system, and the challenges of enrolling experienced centers into clinical trials as device innovation accelerates.

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Get the BackTable app
https://www.backtable.com/app

---

This podcast is supported by

Inari Medical
https://www.inarimedical.com/flowtriever-system

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Timestamps

00:00 - Introduction
01:24 - Building a PERT Team
04:59 - Trials Shaping PE Care
10:20 - Why New Guidelines Now
14:06 - New Risk Categories Explained
19:51 - Applying Guidelines Locally
23:34 - What Is C1 Risk
27:52 - New D Category Explained
30:33 - Evidence for Aggressive Therapy
33:31 - How PERT Teams Communicate
38:22 - Upcoming PE Trials Pipeline
43:42 - Program Growth and High Risk Trials
45:46 - Closing Remarks

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More about this episode

The conversation highlights the growth of catheter-directed lysis and mechanical thrombectomy, the rationale and practical impact of the new Category D for incipient cardiopulmonary failure (including normotensive shock), and the incorporation of PESI, sPESI, and Hestia for risk assessment. Additional topics include decision-making for low-risk patients, lactate and biomarkers for identifying higher-risk cases, communication strategies within PERT teams, AI-enabled risk stratification, and a preview of upcoming trials (PEITHO, PRAGUE-26, PEERLESS-2, PE-TRACT, and PERSEVERE) that are set to further transform PE care.

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Resources

Management of Massive and Submassive Pulmonary Embolism, Iliofemoral Deep Vein Thrombosis, and Chronic Thromboembolic Pulmonary Hypertension: A Scientific Statement From the American Heart Association
https://pubmed.ncbi.nlm.nih.gov/21422387/

Surgical Management and Mechanical Circulatory Support in High-Risk Pulmonary Embolisms: Historical Context, Current Status, and Future Directions: A Scientific Statement From the American Heart Association
https://pubmed.ncbi.nlm.nih.gov/36688837/

Interventional Therapies for Acute Pulmonary Embolism: Current Status and Principles for the Development of Novel Evidence: A Scientific Statement From the American Heart Association
https://pubmed.ncbi.nlm.nih.gov/31585051/

Ultrasound-Facilitated, Catheter-Directed Fibrinolysis for Acute Pulmonary Embolism
https://pubmed.ncbi.nlm.nih.gov/41910345/

PEERLESS II: A Randomized Controlled Trial of Large-Bore Thrombectomy Versus Anticoagulation in Intermediate-Risk Pulmonary Embolism
https://pubmed.ncbi.nlm.nih.gov/39132600/

Rationale and design of the PE-TRACT trial: A multicenter randomized trial to evaluate catheter-directed therapy for the treatment of intermediate-risk pulmonary embolism
https://pubmed.ncbi.nlm.nih.gov/39638275/

Reduced-Dose Intravenous Thrombolysis for Acute Intermediate–High-risk Pulmonary Embolism: Rationale and Design of the Pulmonary Embolism International THrOmbolysis (PEITHO)-3 trial
https://pubmed.ncbi.nlm.nih.gov/34560806/

Design and rationale of the PERSEVERE study: a randomized controlled trial of large-bore mechanical thrombectomy versus the standard of care for high-risk pulmonary embolism
https://pubmed.ncbi.nlm.nih.gov/41453591/

Design and rationale of PRAGUE-26: a multicentre, randomised trial of catheter-directed thrombolysis for intermediate-high risk acute pulmonary embolism
https://pubmed.ncbi.nlm.nih.gov/40464677/

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

Are the latest pulmonary embolism guidelines changing how you risk-stratify and intervene on acute PE? In this episode of BackTable Cardiology, host Dr. Hady Lichaa interviews Dr. Sanjum Sethi of Columbia University Medical Center about the evolving management of pulmonary embolism (PE) and the major updates reflected in the newest guidelines. They review the new A–E risk classification system, key updates to systemic thrombolysis recommendations, and the expanding role of catheter-based therapies as randomized evidence emerges, highlighting how these changes are shaping PERT protocols, influencing clinical decision-making, and affecting patient outcomes.

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Get the BackTable app
https://www.backtable.com/app

---

Timestamps

00:00 - Introduction
01:40 - Major Guideline Changes
13:26 - Essential Components of PERT Calls
16:38 - Assessing Clot Burden
24:32 - When To Prioritize Surgical Management
30:15 - Importance of RV Function
31:26 - Heparin Versus LMWH
37:58 - TPA Dosing
43:42 - Thrombectomy Devices And Guidelines
50:19 - Future Technology

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More about this episode

The doctors discuss key practice updates, including the new Class I recommendation to incorporate lactate into shock assessment and the downgrade of systemic thrombolysis for highest-risk PE patients while highlighting the expanding evidence and indications for catheter-based therapies. Dr. Sethi outlines the essential clinical data to gather during PERT calls, including vital signs, RV function, biomarkers, and patient goals, and explains why relying solely on CT thrombus burden can be misleading. They discuss the importance of echocardiography for detecting findings like PFO or clot-in-transit and provide guidance on when to consider surgical intervention or ECMO, how to choose between heparin and LMWH, and the nuanced decision-making behind selecting catheter-directed thrombolysis versus mechanical thrombectomy.

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Resources

Dr. Hady Lichaa’s Provider Profile
https://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa

Dr. Sanjum Sethi’s Provider Profile
https://www.columbiacardiology.org/profile/sanjum-s-sethi-md-mph

2026 AHA/ACC/ACCP/ACEP/CHEST/SCAI/SHM/SIR/SVM/SVN Guideline for the Evaluation and Management of Acute Pulmonary Embolism in Adults
https://www.ahajournals.org/doi/10.1161/CIR.0000000000001415?utm_campaign=sciencenews25-26&utm_source=science-news&utm_medium=phd-link&utm_content=phd-2-19-26

Pharmacomechanical Catheter-Directed Thrombolysis With the Bashir Endovascular Catheter for Acute Pulmonary Embolism: The RESCUE Study https://www.jacc.org/doi/10.1016/j.jcin.2022.09.011

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

Could persistent dyspnea after a “resolved” PE be more than just deconditioning or diastolic dysfunction? In this episode of BackTable Cardiology, Dr. Hady Lichaa hosts interventional cardiologist and vascular medicine specialist Dr. Vladimir Lakhter, to discuss the diagnosis and management of CTEPH and chronic thromboembolic disease (CTED). They review the prevalence of CTEPH following pulmonary embolism, common delays in diagnosis, and why symptoms such as dyspnea are often misattributed to conditions like diastolic dysfunction.

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Get the BackTable app
https://www.backtable.com/app

---

Timestamps

00:00 - Introduction
02:40 - Defining CTEPH
07:00 - Diagnostics for Detection
12:02 - Treatment Considerations
16:08 - Anatomy Challenges
22:03 - Device Options and Techniques
29:40 - BPA Procedure
39:50 - Interpreting Angiographic Appearance of CTEPH
48:10 - BPA Challenges and Risks
52:06 - Diuretics
55:10 - Post BPA Diagnostics and Complications
01:02:42 - Treatment Endpoints
01:06:10 - Continuing Education and Expert Resources
01:08:41 - Closing Thoughts

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More about this episode

Dr. Lakhter outlines a practical diagnostic workup, emphasizing the Ventilation-Perfusion (V/Q) scan as the key screening test, supplemented by thin-cut CT pulmonary angiography and transthoracic echocardiography (TTE). He then explains how treatment decisions are made within a multidisciplinary framework, balancing medical therapy, surgical pulmonary endarterectomy (the curative gold standard for surgically accessible disease), and balloon pulmonary angioplasty (BPA) for patients with distal disease, residual pulmonary hypertension after surgery, or those who are not surgical candidates.

Drs. Lichaa and Lakhter dive into a detailed procedural overview of BPA, including pulmonary artery anatomy resources, pulmonary angiography technique, access and equipment selection, lesion classification, and intraprocedural assessment using pressure wires and venous return patterns. Dr. Lakhter shares practical strategies to minimize complications, including undersized balloon sizing to reduce reperfusion pulmonary edema, routine post-procedure diuresis, and management of complications such as pulmonary artery injury and tamponade using Gelfoam, coils, and, in rare cases, vascular plugs. They finish the conversation with a closer look at typical BPA staging and treatment endpoints.

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Resources

Dr. Hady Lichaa’s Provider Profile
https://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa

Dr. Vladimir Lakhter’s Provider Profile
https://www.templehealth.org/doctors/vladimir-lakhter

Balloon Pulmonary Angioplasty (BPA) for Treatment of Chronic Thromboembolic Pulmonary Hypertension (CTEPH)
https://pubmed.ncbi.nlm.nih.gov/11136677/

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

What do the very first TAVRs, rotational atherectomies, and angioplasty studies have in common? Dr. William O’Neill, an esteemed interventional cardiologist whose collaboration and innovation have shaped the field of interventional cardiology. In this episode of BackTable Cardiology, host Dr. Babar Basir welcomes his mentor Dr. William O’Neill. Together, they trace the evolution of interventional cardiology through personal stories, groundbreaking research, and the lasting impact of mentorship and teamwork on the specialty’s past, present, and future.

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Get the BackTable app
https://www.backtable.com/app

---

Timestamps

00:00 - Introduction
11:49 - Intracoronary Streptokinase Breakthrough
14:28 - Birth of Angioplasty: Initial Studies
23:20 - Primary PCI Proves Itself
28:29 - TAVR Breakthroughs
35:32 - Mentorship Lessons
40:17 - Future Cardiology Frontiers
46:22 - Presidential Heart History
53:51 - Conclusion

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More about this episode

Dr. O’Neill details the evolution from bedrest-era MI care to intracoronary streptokinase and the advent of reperfusion, his early exposure to balloon angioplasty, and the pivotal studies that proved primary PCI’s superiority over thrombolytics amidst controversy. He explores how physician–engineer collaboration enabled innovations such as aortic valvuloplasty and early US TAVR, including the procedural challenges and regulatory hurdles faced. The episode also covers Dr. O’Neill’s mentorship philosophy, his optimism for the future of cardiology, including breakthroughs in cardiomyogenesis, xenotransplantation, and denervation therapies and his plan to remain up-to-date in the cardiology scene while beginning research on past presidents’ heart disease.

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Resources

Dr. Babar Basir’s physician profile
https://www.scai.org/mir-b-basir-do-fscai

Dr. William O’Neill’s physician profile
https://www.scai.org/william-w-oneill-md-mscai

Thrombolysis and angioplasty in myocardial infarction (TAMI) trial
https://www.jacc.org/doi/10.1016/S0735-1097%2887%2980430-8

Thrombolysis in Myocardial Infarction (TIMI) Study Group
https://timi.org/about-timi/

Health-related quality of life one month after thrombolysis or primary PCI in patients with ST-elevation infarction. A DANAMI-2 sub-study.
https://www.tandfonline.com/doi/10.1080/14017430510035989?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub%20%200pubmed

Patient age and results of balloon aortic valvuloplasty: The mansfield scientific registry experience
https://www.sciencedirect.com/science/article/pii/0735109791908738

Percutaneous Transcatheter Implantation of an Aortic Valve Prosthesis for Calcific Aortic Stenosis: First Human Case Description
https://www.ahajournals.org/doi/10.1161/01.CIR.0000047200.36165.B8

Primary left ventricular unloading with delayed reperfusion in patients with anterior ST-elevation myocardial infarction: Rationale and design of the STEMI-DTU randomized pivotal trial
https://pubmed.ncbi.nlm.nih.gov/36058253/

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

From clot to clear flow, minimally invasive aspiration devices are PAVE-ing the way for safer treatment of endocarditis and cardiac masses. In this BackTable Cardiology episode, host Dr. Hady Lichaa sits down with Dr. Abdallah El Sabbagh to discuss percutaneous continuous-flow aspiration for right- and select left-sided endocarditis and cardiac masses.

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Get the BackTable app
https://www.backtable.com/app

---

This podcast is supported by

Angiodynamics
https://9zfaiv.short.gy/cardiovascular-backtable

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Timestamps

00:00 - Introduction
03:43 - Lessons in Fibroelastoma
12:01 - Imaging Workup
14:24 - Transesophageal Echocardiography (TEE) vs Intracardiac Echocardiography (ICE)
17:52 - AngioVac System Components
20:33 - Access Strategy, Sheath Size and Flow Rates
23:41 - Adjunct Tools and Retrieval Options
31:35 - Using Continuous Aspiration
47:16 - Percutaneous AngioVac Vegetation Extraction (PAVE) Trial
53:17 - Future Devices Wishlist

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More about this episode

Dr. El Sabbagh provides guidance on removing papillary fibroelastomas, emphasizing matching technique to mass characteristics and combining tools such as continuous aspiration with electrosurgical snaring to address adherent stalks. Their conversation covers patient selection for off-label endocarditis intervention, including intravenous drug use and Cardiac Implantable Electronic Device (CIED) lead infections, use of aspiration as definitive therapy, and imaging/workflow preferences. Dr. El Sabbagh details the AngioVac system, access strategies, adjunct devices, mitigating complications, and registry outcomes. He touches on the need for prospective studies, including the Percutaneous AngioVac Vegetation Extraction (PAVE) clinical trial. To finish the conversation, Drs. Lichaa and El Sabbagh look ahead to building future devices and provide advice on creating multidisciplinary programs as well as training pathways.

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Resources

Dr. Hady Lichaa’s Provider Profile
https://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa

Dr. Abdallah El Sabbagh’s Provider Profile
https://www.mayoclinic.org/biographies/el-sabbagh-abdallah-m-d/bio-20466764

Percutaneous AngioVac Vegetation Extraction (PAVE) to Remove Right Heart Vegetations in Patients With Infective Endocarditis - PAVE Clinical Trial
https://clinicaltrials.gov/study/NCT07282002

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

Below-the-knee (BTK) arterial disease remains one of the more challenging areas in vascular care, particularly in patients with chronic limb-threatening ischemia (CLTI), where heavy calcification complicates endovascular treatment. As new calcium-modifying technologies emerge, an important question remains: what evidence supports their use in BTK interventions? In this episode of BackTable Vascular & Interventional, host Dr. Sabeen Dhand speaks with vascular surgeon Dr. Paul Foley of Doylestown Health about the Disrupt BTK II clinical trial from Shockwave Medical, which evaluates the performance of peripheral intravascular lithotripsy (IVL) in heavily calcified BTK disease.

---

Get the BackTable app
https://www.backtable.com/app

---

This podcast is supported by

Shockwave Medical
https://shockwavemedical.com/

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Timestamps

00:00 - Introduction
08:20 - Evolution of Below-the-Knee Treatments
11:10 - Differences in BTK Calcification
13:13 - Imaging and Technology in BTK Interventions
15:18 - Disrupt BTK II Trial Data and Results
23:17 - Introduction to the Javelin Device
26:39 - Technique Considerations with Javelin
28:36 - Comparing Javelin and E8
31:17 - Future Directions for Lithotripsy Technology
35:30 - Skepticism Around IVL in BTK Disease
38:47 - Final Thoughts

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More about this episode

Dr. Foley begins by outlining his training and the evolution of his vascular surgery practice, setting the stage for a broader discussion on how BTK interventions have changed over the past decade. The conversation explores shifts in access strategies, procedural approaches, and the unique characteristics of calcification encountered in CLTI. Because BTK calcium differs from calcification seen elsewhere in the peripheral vasculature, imaging and device selection play a particularly important role when planning IVL-based therapies. Dr. Foley reviews the design and outcomes of the Disrupt BTK II trial, where devices such as the Shockwave M5+ and S4 catheters were used to modify calcified plaque, demonstrating encouraging safety and performance signals.

The discussion then turns to emerging technologies, including Shockwave’s Javelin catheter, designed to deliver focused pressure waves to fracture dense calcium within peripheral arteries. Dr. Foley describes how the device fits into BTK workflows, including technique considerations and its use alongside adjunctive therapies such as balloon angioplasty. The episode also addresses the ongoing skepticism surrounding IVL in BTK disease, emphasizing the need for careful patient selection, procedural precision, and continued multidisciplinary collaboration as the field works to refine treatment strategies and improve outcomes for patients with peripheral artery disease (PAD).

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Resources

Disrupt BTK II Trial
https://www.jvascsurg.org/article/S0741-5214(24)02063-9/fulltext

---

BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

Small vessels can have a major impact. Are you missing the hidden culprit of chest pain? In this episode of BackTable Cardiology, host Dr. Hady Lichaa welcomes Yale Interventional Cardiologist Dr. Samit Shah to discuss Coronary Microvascular Dysfunction (CMD) and Angina with No Obstructive Coronary Arteries (ANOCA). Their discussion demonstrates how coronary function testing turns a historically vague diagnosis into actionable phenotyping that can dramatically improve treatment efficacy and patient symptoms.

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Get the BackTable app
https://www.backtable.com/app

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Timestamps

00:00 - Introduction
01:53 - Coronary Microvascular Dysfunction (CMD) Overview
10:55 - Cath Lab Workflow Tips
19:28 - Structural CMD: Discordant CFR and IMR Values
26:59 - Vasospastic Phenotypes
28:28 - Chest Pain Case: Syncope and Arrest Risk
33:31 - Treatment and ACh Testing
39:10 - Mixed Physiology Pharmacotherapy
49:45 - Myocardial Bridge Workup
55:19 - Workflow, Reimbursement, and Future Therapies
58:11 - Closing and Signoff

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More about this episode

Dr. Shah breaks down clinical presentations and cath lab findings of epicardial vasospasm, microvascular spasm, and endothelial dysfunction, outlining how phenotype and physiology influence treatment. He explains how to perform both Coronary Flow Reserve (CFR) and Index of Microcirculatory Resistance (IMR) testing, incorporating examples of interpretation of abnormal values. The physicians discuss COVADIS criteria for vasospastic angina, vasospasm and cardiac arrest considerations, and myocardial bridges in LAD-PCI. The episode covers door-to-discharge care for CMD: identification of phenotype via patient case walk-throughs, practical cath lab workflow, and recommendations for tailored pharmacotherapy.

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Resources

Dr. Hady Lichaa’s Provider Profile
https://healthcare.ascension.org/find-care/provider/1336267533/hady-lichaa

Dr. Samit Shah’s Provider Profile
https://medicine.yale.edu/profile/samit-shah/

COVADIS Criteria for vasospastic angina
https://covadis.online/definitions/

A doppler flow probe for canine main left coronary arteries
https://journals.physiology.org/doi/abs/10.1152/jappl.1974.37.2.256?journalCode=jappl

ChaMP-CMD: A Phenotype-Blinded, Randomized Controlled, Cross-Over Trial
https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066680

Presence and Relevance of Myocardial Bridge in LAD-PCI of CTO and Non-CTO Lesions

https://pubmed.ncbi.nlm.nih.gov/38340105/

DEFINE GPS Trial
https://clinicaltrials.gov/study/NCT04451044

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BackTable Cardiology is the go-to podcast for interventional cardiologists, cardiac surgeons, and other healthcare professionals that manage cardiovascular conditions.

Download the free BackTable app to get early access to new episodes, cases, and courses curated by physicians in your specialty.

► https://www.backtable.com/app

Summary

This week, the coronary sinus isn’t the only thing getting reduced! Dr. Jai Khatri and Dr. Ziad Ali join this BackTable Brief to share strategies for reducing enrollment barriers for the COSIRA II coronary sinus reducer trial. They discuss refractory angina, emerging evidence for microvascular angina, and strategies to help patients achieve stable medical therapy and avoid resetting trial eligibility.

TIMESTAMPS

00:00 - Introduction

01:46 - Maintaining Patients Eligibility

04:20 - Treadmill Test Reproducibility

07:16 - Patient Stories And Outcomes

11:39 - CTO vs. COSIRA-II Trial Candidacy

16:57 - Microvascular Angina: Evidence and Outlook

CHECK OUT THE FULL EPISODE

COSIRA II: Managing Refractory Angina in Clinical Practice

https://www.backtable.com/shows/cardiology/podcasts/14/cosira-ii-refractory-angina-challenges-treatment-strategies

RESOURCES

COSIRA-II Trial
https://clinicaltrials.gov/study/NCT05102019

Coronary sinus reducers: the hourglass-shaped stents that might be able to take patients back to angina-free times. In this BackTable Cardiology Brief, Dr. Jai Khatri and Dr. Ziad Ali discuss patient selection, treatment algorithms, and recent, clinical-trial backed technology for treating diffuse, multi-vessel atherosclerotic disease. They emphasize staged PCI, careful counseling, and setting realistic expectations when angiographic success doesn’t translate to symptom relief.

Notably, the episode introduces the coronary sinus reducer, tracing the stent’s roots back to the Beck procedure of the 1950s. Drs. Jai and Khatri review the stent’s mechanism in the coronary sinus and review key coronary sinus reducer trials: COSIRA and COSIRA-II. The delve into COSIRA-II’s design, inclusion criteria, and best practices and recommendations for enrolling patients.

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Timestamps

00:00 - Introduction

00:59 - Diffuse Disease Challenges

02:42 - Patient Communication: Setting Expectations

05:06 - Treatment Algorithms: PCI vs CABG

07:22 - When PCI Fails Symptoms

08:35 - Coronary Sinus Reducers

10:52 - COSIRA Evidence

12:01 - COSIRA II Design

13:13 - Why Sham Control Matters

14:30 - Reducer Procedure Walkthrough

16:54 - Risks And Safety

18:41 - Enrollment And Criteria

20:11 - Wrap Up And Credits

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Check out the full episode

COSIRA II: Managing Refractory Angina in Clinical Practice

https://www.backtable.com/shows/cardiology/podcasts/14/cosira-ii-refractory-angina-challenges-treatment-strategies

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Resources

COSIRA-II Trial

https://clinicaltrials.gov/study/NCT05102019