Dr. Rodger Murphree—board-certified nutritional specialist, chiropractic physician, and functional medicine expert—breaks down what neurotransmitters are, why so many people with fibromyalgia, anxiety, depression, and brain fog are depleted in them, and why prescription antidepressants and benzodiazepines often miss the root problem. He explains the “gasoline additive vs empty tank” issue with SSRIs/SNRIs, outlines risks like sleep disruption, down-regulation of serotonin receptors, CoQ10 and melatonin depletion, and the domino effect of multi-drug symptom management.

From there, Dr. Murphree reframes mood and pain disorders as nutrient and amino-acid driven chemistry problems that can frequently be improved with orthomolecular strategies. He walks through the major neurotransmitter families—serotonin, GABA, dopamine, norepinephrine, and endogenous opioids—showing how they’re built from dietary amino acids plus key cofactors like B vitamins, magnesium, folate, B12, and omega-3s. Listeners learn a practical “brain function questionnaire” method for spotting likely deficiencies, which calming supports to start first, and how to layer in stimulating supports after stability improves. The training is educational and encourages working with a healthcare professional before changing any prescription regimen.

(00:00) Welcome and goals for today

(02:10) Why mood and fatigue tie to brain chemicals

(05:20) The antidepressant reality check

(09:40) Benzodiazepines risks and dependence

(14:30) CoQ10 and melatonin depletion

(18:10) SSRI side effects and drug stacking

(22:50) Sleep as the foundation

(27:10) Gasoline additive vs empty tank

(31:00) What neurotransmitters are

(34:20) Amino acids and cofactors explained

(38:40) Serotonin pathway and 5-HTP

(43:00) B vitamins, folate, and B12

(47:30) Omega-3 vs omega-6 balance

(52:10) Brain function questionnaire overview

(54:00) Opioid group and DLPA

(58:20) GABA group and calming supports

(1:02:40) Dopamine group and motivation

(1:06:40) Norepinephrine group and drive

(1:10:40) Serotonin group and fibro signs

(1:13:30) Start calming first, then stimulating

(1:16:30) Where to take the questionnaire

(1:19:20) Programs, books, and next steps

Work with Dr. Murphree

Consultations & Programs – ⁠⁠⁠⁠yourfibrodoctor.com⁠⁠⁠⁠

More About Dr. Rodger Murphree

Website: ⁠⁠⁠⁠superhealthyhuman.com⁠⁠

Instagram: ⁠⁠⁠⁠@drrodgermurphree⁠⁠

Facebook: ⁠⁠⁠⁠Dr. Rodger Murphree, Functional Medicine Expert⁠⁠

⁠⁠⁠⁠⁠⁠⁠YouTube: ⁠⁠⁠⁠Dr. Rodger Murphree⁠⁠⁠⁠

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