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Labour's Andy Burnham has won the Makerfield by-election, paving the way for him to challenge Keir Starmer as prime minister.

"Everyone knows that politics isn't working," he said during his victory speech.

Burnham gained almost 25,000 votes, beating Reform UK's Robert Kenyon by more than 9,000 votes.

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How one man survived a cardiac arrest that left him clinically dead for ten minutes after a cricket-ball-sized blood clot caused a medical miracle that left even his doctors in shock. 

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A 2000ft fall off a jagged mountain ridge should have been fatal. Instead, one endurance runner survived the drop and managed to run four miles to find his own rescue on a Scottish island.

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The US has confirmed it has lifted its naval blockade of Iranian ports, as the Iran deal comes into effect.

Meanwhile, in a written message Iran's supreme leader says he initially disagreed with the deal, but allowed it to go ahead after assurances from the Iranian president.

Mojtaba Khamenei also says that US President Donald Trump came to the agreement "out of desperation".

Earlier, US Vice-President JD Vance said the 60-day period to reach a final agreement with Iran had begun.

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The US and Iran have signed a 14-point Memorandum of Understanding, triggering a 60-day period to reach a final agreement.

It includes the reopening of the Strait of Hormuz and sets out a $300bn plan for Iran's "reconstruction".

US President Donald Trump has hit out at critics of his deal, saying those accusing him of being soft on Iran were "fools" who might be jealous.

His Iranian counterpart, Masoud Pezeshkian, said the accord was a sign of his country's "national resilience".

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00:00 What's in the deal?

02:02 Who got the better deal?

03:37 US politicians criticise the deal

05:16 Will Israel stop fighting Hezbollah in Lebanon?

07:03 $300 billion aid package to Iran

08:35 What do Americans think?

09:46 How precarious is the next 60 days?

Today, the US and Iran have an agreement which extends the ceasefire between the two countries, and is now signed by US President Trump and Iranian President Masoud Pezeshkian.

Chief International Correspondent Lyse Doucet talks us through what the deal includes, what it means for the strait of Hormuz and oil prices, and where the sticking points may be. Chief North America Correspondent Gary O’Donoghue explains how the deal has been spun and how it has been received in the US.

And, we continue digging into the proposed social media ban with a special guest from Australia. Australian Liberal MP Zoe McKenzie had been calling for this ban since her maiden speech in 2022, she explains how it actually works and what it could take to change how the tech companies protect young people online.

00:25 Iran-US Deal Signing Expected in Switzerland

01:24 Trump Signs Agreement at Versailles as Leaders Respond

03:51 Ceasefire Plan and Questions Over a “Permanent” End to War

06:03 Strait of Hormuz Reopens as Markets and Oil Prices Shift

09:56 Reconstruction Fund and Sanctions Relief Under Scrutiny

14:59 What the Deal Leaves Out: Missiles and Proxies

18:12 Australia’s Social Media Ban and Impact on Children

25:07 Can Platforms Enforce Age Limits and Close Loopholes?

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A violent cattle attack left Mary-Jane needing skin grafts and fighting for her life. She was crushed and dragged along a mountain track before she was rescued and taken to hospital via air ambulance. 

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Children vaccinated at age 12–13 against HPV (human papillomavirus) have close to zero risk of dying from cervical cancer before the age of 30, landmark new research has revealed.

The first study of its kind shows deaths have fallen sharply since school-age girls began being offered it in 2008, and around 200 lives have been saved in England so far thanks to the vaccine.

Between 2020 and 2024, no cervical cancer deaths were recorded in women aged 20 to 24 - the first time that had happened over a five-year period.

Without vaccination, around 23 deaths would have been expected.

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A US-Iran agreement to extend the ceasefire between the two countries has been signed and is now in effect.

President Donald Trump formally signed the deal - which is set to reopen the Strait of Hormuz - while attending the G7 summit in France.

The 14-point agreement says that Iran will never have a nuclear weapon, and also commits a $300bn fund for the "reconstruction and economic development" of the country - although the US is not required to contribute.

The BBC's Caroline Hawley explains what you need to know about the agreement.

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0:00 Papers are signed

0:35 Key points in the agreement

01:38 Who gains the most?

02:08 Did Trump achieve his goals?

03:31 Nuclear weapons agreement

04:57 Iran's protesters

05:59 Impact on economy

07:23 Will it work?

At the peak of her addiction, Izabel was using ketamine daily, sometimes at work. Seeking an escape in Japan, she was instead met by a nine-officer police raid and five months in a prison cell.

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