Bench Boost by Inorganic Ventures

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In this solo episode, Mike dives into titrations — a method that's still essential across industries like environmental testing, manufacturing, and even winemaking. Learn tips for improving accuracy, from proper burette qualification and indicator usage to endpoint detection techniques like quick drops vs. full drops. Mike also shares common troubleshooting advice for colorblindness in titrations, sliding endpoints, and working with high-concentration samples.

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This episode takes a fun detour into the world of chemistry conspiracy theories! Mike Booth explores the science behind chemtrails vs. contrails and explains how you could actually test for elements like aluminum, barium, lead, and lithium in air samples using ICP-OES and ICP-MS. Learn practical tips for sample collection, how to avoid common interferences, and why trace analysis requires extra care with contamination control.

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In this episode, we tackle unexpected high recoveries, caused by internal standard signal timing during ICP analysis. Then we unpack a challenging multi-element blend, involving silver, tungsten, sulfur, rare earths, and more — plus how acid choices and order of addition impact stability. Finally, we dig into a sample prep puzzle for chloride analysis in iron phosphate, offering digestion strategies, matrix compatibility tips, and insights from Dr. Paul Gaines.

These real-world cases are packed with lessons to improve your prep, analysis, and problem-solving in the lab.

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In this episode, we dive into two real-world stability challenges from our lab. First, we explore a custom tune solution prepared in dilute ammonium hydroxide for ICP-MS, designed to improve lab efficiency. Learn how it performed over time and how to use it effectively for short-term use. Then, we dig into an unexpected silver instability in a low-level multi-element blend — traced back to residual chloride from chromium prep.

From method design to trace contamination troubleshooting, this episode is full of practical lessons for anyone working with custom solutions or chasing long-term stability.

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Experiencing issues in your prep or analysis? This episode is full of practical advice to keep your data on track.

Learn how to improve mercury recoveries, including best practices for stabilization in different matrices and container types. We also dive into designing high-concentration multi-element blends, highlighting unexpected incompatibilities and how acid concentration impacts stability. Finally, we discuss anion and IC standard preparation, covering pH control, contamination risks, and tips for preventing nitrite degradation and microbial growth.

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In this episode, we wrap up our glossary discussions with a focus on element speciation — why ICP alone can't distinguish oxidation states and how chromatography can help. We also break down working solutions, explaining how to properly dilute stock standards for analysis. Plus, we discuss matrix effects, covering signal suppression, ionization buffers, and why matrix matching is critical for accuracy.

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In this episode, we continue exploring key terms in elemental analysis, focusing on calibration standards, how they establish accuracy, and why they are essential for reliable results. We also cover internal standards, their role in correcting matrix effects, and best practices for selecting them. Finally, we dive into blank corrections, breaking down calibration blanks, reagent blanks, and method blanks — critical tools for improving data accuracy.

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Fresh from Pittcon 2025, we’re recapping the biggest moments, key industry insights, and what made ICP Alley a must-visit destination! Hear about our experience connecting with customers, tackling live tech support questions, and catching up with industry partners. Plus, we dive into new trends in sample introduction, instrument developments, and technical challenges analysts are facing today.

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In this episode, we unpack fundamental concepts that every ICP analyst should know. Learn what National Metrology Institutes (NMIs) are and why SI traceability is essential for accurate measurements. We also clarify the differences between SRMs, CRMs, RMs, and PCRMs, helping you choose the right standard for your work. Plus, we discuss accuracy vs. precision, measurement uncertainty, and how tolerance impacts your data.

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In this Q&A episode, we answer common questions from ICP analysts, including how to choose between AA and CG product lines for your standards, when certification levels matter, and what documentation differences to expect. We also troubleshoot high recoveries of copper and lead in ICP-OES, exploring possible interferences, calibration curve issues, and internal standard miscalculations. Plus, we break down how internal standard baselines can throw off your results and how to fix them.