Beyond Lifespan Longevity Podcast (English Edition)

You put off a simple task for days, then lose yourself in an interesting project for hours. Your phone keeps pulling you away—and your social media feed keeps telling you it’s ADHD. How do you make sense of it?

In this episode of Beyond Lifespan, medical doctors Mario Gietl and Max Griessinger explore ADHD in adults: attention, dopamine, impulse control and the apparent contradiction of hyperfocus. They discuss why ADHD can go unnoticed for years, why it may be overlooked in women, and how treatment can combine medication with practical support.

In our Community Hotline, a listener asks: “I was diagnosed with ADHD at 41. Can it start in adulthood, or was it missed?” Plus, this episode’s biohack explores sleep timing, morning light and melatonin.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Alcohol may help you fall asleep faster, feel more sociable and relax in the short term. But that effect comes at a cost: less REM and deep sleep, more anxiety and restlessness the next day, and a higher risk of several types of cancer.

In this episode, we explain what alcohol does to the brain and the rest of the body, what causes “hangxiety,” and why the supposedly healthy glass of red wine is based on flawed scientific assumptions. We also discuss practical harm-reduction strategies for people who consciously choose to drink.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Dementia rarely develops overnight. Changes in the brain may begin 20 to 25 years before obvious memory problems appear. That makes early action on modifiable risk factors especially important.

In this episode, we examine 14 modifiable risk factors for dementia and Alzheimer’s disease. We explain why vascular health, blood glucose and blood lipids are closely connected to brain health, how deep sleep and sleep apnea matter, and why hearing loss, vision loss and social isolation are often underestimated.

We also discuss strength and endurance training, a Mediterranean-style diet, omega-3, creatine, homocysteine, learning new languages and hobbies, and who may benefit from ApoE4 genetic testing.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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You take magnesium, melatonin or other sleep supplements and still sleep poorly? The missing piece is probably not another supplement, but the fundamentals.

Mario and Max discuss the most important levers for better sleep: light exposure, caffeine, alcohol, room temperature, late meals, stress, breathing patterns and evening routines. We explain circadian rhythm and sleep pressure, and why morning daylight, evening darkness, a cool bedroom and less stimulation often outperform the next sleep stack.

We also cover blue-light-blocking glasses, daylight lamps, warm showers, sauna, nasal breathing, mouth taping, journaling, box breathing, NSDR and supplements including magnesium, glycine, L-theanine, GABA, melatonin, ashwagandha and apigenin.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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B vitamins are not one substance but a family of eight water-soluble vitamins with very different functions. They are essential for energy metabolism, DNA repair, methylation, homocysteine regulation, blood formation, neurotransmitter synthesis and nerve function. Folate and vitamin B12 deficiencies are surprisingly common, particularly with vegan or vegetarian diets, older age, pregnancy, alcohol use, celiac disease, and medications such as metformin or proton pump inhibitors.

We explain which B vitamins matter most, which forms may be preferable, why methylfolate can be more useful than conventional folic acid, what MTHFR means, and why high-dose vitamin B6 should not be taken long term despite being water-soluble. We also discuss niacin flush, biotin and lab testing, B12 absorption, homocysteine, holotranscobalamin and whether a B-complex or targeted individual supplements make more sense.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Magnesium is one of the most popular supplements, but it is sold in many different forms. Magnesium oxide, citrate, bisglycinate, L-threonate, malate, taurate and blended products may sound similar, yet their tolerability, bioavailability and practical uses can differ.

We compare magnesium forms for sleep and stress, energy and mitochondrial function, muscles and cramps, cardiovascular health and digestion. We also explain why the amount of elemental magnesium on the label is what matters, why fast-acting magnesium sticks are often overrated for acute cramps, when a magnesium complex can make sense, and what to consider regarding dosage, timing and medication interactions.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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HbA1c is the standard marker for long-term blood glucose, but is it enough to detect insulin resistance early? We compare HbA1c, fasting glucose, fasting insulin and HOMA-IR. Blood glucose can remain normal for years while the body compensates with increasingly high insulin, long before type 2 diabetes develops.

We also discuss useful ranges, common testing errors and confounders including iron deficiency, sleep deprivation, stress, menstrual-cycle phase and intense exercise before a blood draw. Finally, we examine muscle mass, strength training, diet, sleep, continuous glucose monitors and weight loss—and why insulin resistance is often reversible when detected early.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Collagen is a popular supplement for skin, joints and connective tissue, yet headlines about its effectiveness are often contradictory. We review the current research and explain where collagen may be useful and where expectations tend to exceed the evidence.

We cover the relevant collagen types, why hydrolyzed collagen peptides are the main supplemental form, and the roles of vitamin C and other cofactors. Collagen may be particularly relevant for athletes, runners, people with high joint loads and women during or after menopause. We also discuss vegan alternatives, quality differences, and potential concerns such as heavy-metal contamination or kidney stones at very high doses.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Omega-3 fatty acids play an important role in heart health, brain function and the resolution of inflammation, yet many people do not reach an optimal status. We explain why the omega-6-to-omega-3 balance matters, why ALA from flaxseed oil or walnuts may not provide enough EPA and DHA, and how genetics affects conversion.

We also cover the Omega-3 Index, the arachidonic-acid-to-EPA ratio, trans fats, resolvins and other specialized pro-resolving mediators. Finally, we compare fish oil, algae oil and other sources, and explain quality markers including triglyceride form, ethyl esters, oxidation and TOTOX value, plus practical strategies for diet, testing and supplementation.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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Coffee improves alertness, but not equally for everyone. We explain how caffeine blocks adenosine and sleep pressure, how tolerance, crashes and withdrawal headaches develop, and which dose ranges matter in practice.

We compare caffeine levels in filter coffee, espresso, tea, matcha, energy drinks, pre-workouts and decaf. We also examine fast and slow caffeine metabolism through CYP1A2, caffeine sensitivity through ADORA2A, and factors that change caffeine half-life—including smoking, oral contraceptives, grapefruit, alcohol and pregnancy. Finally, we look at sports performance, longevity research and how to determine your personal cutoff time for the last coffee of the day.

Disclosure: This is an AI-translated English version of the original German episode, using synthetic versions of the hosts’ voices with their consent.

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