Beyond the Endpoint

What do championship sports teams and successful research institutions have in common?

In the season finale of Beyond the Endpoint, Dr. Adrian Hernandez joins hosts Manesh Patel and Emily O’Brien to break down what clinical research institutions can learn from their counterparts on the court. From basketball dynasties to resilient mindsets, Dr. Hernandez offers a powerful playbook on building strong research systems, prioritizing patients, and why sharing “negative” results matters.

Don’t miss the wrap-up to Season 1!

🔗 Access resources related to this episode https://dcri.org/blog/ep-10-playing-advance-care-championship-mindset-clinical-research

In this new episode of the Beyond the Endpoint series, “Beyond the Headlines,” hosts Emily O’Brien and Manesh Patel break down what’s you should know about these trending medical topics.

From hype to headlines—get clinical insight that goes deeper.

Access resources related to this episode https://dcri.org/blog/ep-9-beyond-headlines

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Why do people volunteer for clinical trials — and what should they know before doing so?

In this episode of Beyond The Endpoint, we explore common questions, reasons, and myths about clinical trial participation. Hosts Manesh Patel and Emily O’Brien talk with guest Krista Camuglia, a Research Practice Manager with the Duke Heart Center Clinical Research Unit, who brings unique insights thanks to her work on the frontlines of research coordination.

🎙️ Listen to "Part 1: Why Participate in Clinical Research?" https://dcri.org/blog/ep-7-stepping-why-participate-clinical-research

In this episode, cancer survivor Katie Ortman-Doble opens up about her journey through clinical research and why she chose to participate. Hosts Emily O’Brien and Manesh Patel, joined by Jenny Cook, talk about the life-saving potential of clinical trials and the real impact they have on patients and science.

Hear Katie’s inspiring story and the reasons behind her decision to join a trial.

🔗 Access resources related to this episode https://dcri.org/blog/ep-7-stepping-why-participate-clinical-research

In this episode of Beyond the Endpoint, former FDA commissioner Dr. Robert Califf joins hosts Manesh Patel and Emily O’Brien to discuss critical challenges shaping the future of patient care. From misinformation to regulatory science to the financialization of healthcare, Dr. Califf has unique insight into the evolving healthcare landscape and the role of data in improving patient outcomes.

🔗 Access resources related to this episode https://dcri.org/blog/ep-6-bridging-science-and-policy-conversation-dr-robert-califf

Ozempic curbing alcohol cravings, ADHD linked to shorter life expectancy, and an NBA rising star diagnosed with DVT—what does the science actually say? In this first episode of Beyond the Headlines, a new Beyond the Endpoint series, hosts Emily O’Brien and Manesh Patel break down the research behind these trending stories.

Access resources related to this episode https://dcri.org/blog/ep-5-beyond-headlines

Smartwatches, fitness trackers, and health data—how are wearables reshaping clinical research? In this episode, Dr. Marat Fudim joins us for an insightful discussion on how wearable technology is shaping the way we monitor health and conduct research. Topics include:

• Are wearables improving patient care or just tracking steps?

• How do researchers use wearable data in clinical trials?

•What are the biggest challenges in integrating this tech?

🎙️ Listen now and explore the possibilities of wearable health tech!

🔗 Access resources related to this episode https://dcri.org/blog/ep-4-wearables-clinical-research-data-trends-and-challenges

In this episode of Beyond the Endpoint, Emily O’Brien and Manesh Patel sit down with Leslie Curtis, former senior FDA policy advisor, to explore the FDA’s role in balancing science, public health, and regulation, along with how political transitions influence clinical research, healthcare funding, and the approval process for new treatments.

🔗 Access resources related to this episode https://dcri.org/blog/ep-3-intersection-politics-and-medicine-impacts-clinical-practice

Reducing hypertension risk isn’t just about cutting salt. This week on Beyond The Endpoint, Emily O’Brien, Manesh Patel, and Jenny Cook talk with Dr. Dhruv Kazi about the complex public health battle against hypertension. From interventions to strategies for patient and physician adherence, this episode covers scalable solutions to change the future of hypertension.

🔗 Access resources related to this episode https://dcri.org/blog/ep-2-bending-curve-rewriting-future-hypertension

In this episode of "Beyond the Endpoint," hosts Emily O'Brien and Manesh Patel are joined by guest host Jenny Cook to discuss grief among healthcare providers with Tony Galanos, a researcher and physician at the Duke University School of Medicine. Galanos — "Dr. G" as he's called around Duke — shares insights from his 12-year program helping other clinicians to address and process the grief that can be an inevitable part of their work. He highlights the emotional toll that healthcare work can take and the importance of acknowledging and processing grief. The episode explores the concept of the "hidden curriculum" in medical training, the practice of "the pause" after intense resuscitation efforts, and also dives into how everyone can better manage their own grief after losing a loved one.

🔗 Access resources related to this episode https://dcri.org/blog/ep-1-caring-through-loss-role-grief-clinical-settings