The Giants may be without rookie receiver Malik Nabers, who is in concussion protocol. This means that second-year receiver Jalin Hyatt will need to step up. The team's running game is also wounded, with Devin Singletary missing Wednesday's practice with a sore groin.

Seattle's got its own injury list to worry about. Starting DT Byron Murphy and LB Boye Mafe were among the four players held off of their walk-thru session. Six other starters (four on defense, two on offense) were listed as limited.

We discussed all that and more, including listener questions on the latest Big Blue Breakdown podcast episode.

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