In which Martin Chalfie, a professor of Biological Sciences at Columbia University and Nobel laureate recognized for his contribution to the development of green fluorescent protein (GFP), and Sophia discuss the applications of GFP and his current research on the development and function of touch receptor neurons (TRNs) using the nematode Caenorhabditis elegans. Dr. Chalfie highlights the versatility of GFP as a tool for studying biological processes, including the development and function of neurons. He explains the regulation of TRNs by transcription factors and transduction channels and how studying their development and function can provide insights into sensory perception.