My guest is Matt Abrahams, lecturer at Stanford Graduate School of Business and a world expert in communication and public speaking. He explains how to speak with clarity and confidence and how to be more authentic in your communication in all settings: public, work, relationships, etc. He shares how to eliminate filler words ("umm"-ing), how to overcome stage fright and how to structure messages in a way that makes audiences remember the information. He also shares how to recover gracefully if you "blank out" on stage and simple drills and frameworks that dramatically improve spontaneity, storytelling and overall communication effectiveness. People of all ages and communication styles will benefit from the practical, evidence-supported protocols Matt shares to help you communicate with greater confidence and impact.

Read the episode show notes at hubermanlab.com.

Pre-order Andrew's book Protocols: https://go.hubermanlab.com/protocols

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

Eight Sleep: https://eightsleep.com/huberman

BetterHelp: https://betterhelp.com/huberman

Joovv: https://joovv.com/huberman

Mateina: https://drinkmateina.com/pages/store-locator

Function: https://functionhealth.com/huberman

Timestamps

(0:00) Matt Abrahams

(3:21) Public Speaking Fear, Status; Speech Delivery

(5:36) Speech, Connection, Credibility; Authenticity

(9:05) Monitoring, Self-Judgement; Memorization, Tool: Object Relabeling Exercise

(13:13) Sponsors: Eight Sleep & BetterHelp

(15:40) Cadence & Speech Patterns; Lego Manuals, Storytelling & Emotion

(19:18) Visual vs Audio Content, Length, Detail

(23:19) Understanding Audience's Needs, Tool: Recon – Reflection – Research

(24:25) Judgement in Communication, Heuristics

(27:33) Questions, Responding to the Audience, Tool: Structuring Information

(31:34) Feedback & Observation; Tools: Three-Pass Speech Review; Communication Reflection Journal

(39:09) Movement, Stage Fright, Content Expertise

(42:54) Sponsors: AGZ by AG1 & Joovv

(45:34) Multi-Generation Communication Styles & Trust; Curiosity, Conversation Turns

(50:32) Linear vs Non-Linear Speech, Tool: Tour Guide Expectations

(53:21) Develop Communication Skills, Audience Size, Tools: Distancing; Practicing

(1:01:43) Tool: Improv & Agility; Great Communication Examples; Divided Attention

(1:09:36) One-on-One Communication vs Public Speaking

(1:11:00) Sponsor: Mateína

(1:12:00) Neurodiversity, Introverts, Communication Styles; Writing & Editing

(1:16:30) Calculating Risk, Tool: Violating Expectations & Engaging Audience

(1:21:20) Authenticity, Strengths, Growth & Improv

(1:23:23) Damage Control, Tools: Avoid Blanking Out; Contingency Planning, Silence

(1:30:32) Nerves, Tool: Breathwork; Spontaneous Communication; Beta-Blockers

(1:34:29) Communication Hygiene, Caffeine, Tools: NSDR/Yoga Nidra; Vestibular System & Sleep

(1:40:08) Conversation Before Speaking; Delivering Engaging Speeches

(1:42:56) Sponsor: Function

(1:44:43) Anticipation, Tool: Introduce Yourself; Connect to Environment, Phones

(1:51:30) Customer Service & Kids Jobs; Tool: Role Model Communication; COVID Pandemic

(1:56:04) Quiet But Not Shy, Extroverts; Social Media Presence

(2:00:25) Martial Arts, Sport, Running, Presence & Connection

(2:04:16) Apologizing; Communication Across Accents & Cultures

(2:07:36) Interruptions, Tools: Paraphrasing; Speech Preparation

(2:10:57) Public Speaking Fear, Tool: Envision Positive Outcome; Arguments & Mediation

(2:13:19) Omit Filler Words, Tool: Landing Phrases; Time & Storytelling

(2:16:52) Asking For a Raise; Poor Communicators & Curiosity; Memorization

(2:19:49) Pre-Talk Anxiety Management; Acknowledgements

(2:23:47) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

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In this Huberman Lab Essentials episode, my guest is Dr. Jack Feldman, PhD, a Distinguished Professor of Neurobiology at the University of California, Los Angeles, and a leading expert in the science of breathing.

We explain the mechanics of breathing and the neural circuits that generate and regulate our breathing rhythm. We also discuss how breathing patterns profoundly influence mental states, including their role in reducing anxiety and enhancing emotional resilience. Dr. Feldman also shares practical tools, such as box breathing for daily performance and magnesium L-threonate supplementation to support cognitive health and longevity.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

Mateina: https://drinkmateina.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Timestamps

00:00:00 Jack Feldman

00:00:23 Breathing Mechanics, Diaphragm; Pre-Bötzinger Complex & Breath Initiation

00:03:25 Nose vs Mouth Breathing

00:04:23 Sponsor: Mateina

00:05:24 Active Expiration & Brain; Retrotrapezoid Nucleus

00:08:32 Diaphragm & Evolution; Lung Surface Area & Alveoli, Oxygen Exchange

00:12:56 Diaphragmatic vs Non-Diaphragmatic Breathing

00:14:23 Physiological Sighs: Frequency & Function; Polio & Ventilators

00:18:21 Sponsor: AGZ by AG1

00:19:52 Drug Overdose, Death & Gasps

00:21:38 Meditation, Slow Breathing & Fear Conditioning Study

00:25:28 Mechanistic Science in Breathwork Validation; Breath Practice & Reduced Fear

00:27:21 Breathing & Emotional/Cognitive State, Olfaction, Vagus Nerve

00:29:44 Carbon Dioxide, Hyperventilation & Anxiety

00:31:21 Sponsor: Eight Sleep

00:32:47 Breathing, Emotion & Autonomic Processes Coordination; Depression & Breath Practices

00:36:43 Tool: Breathwork Practices, Box Breathing, Tummo, Wim Hof

00:38:46 Magnesium L-Threonate & Cognitive Enhancement; Compound Refinement

00:44:28 Clinical Trial, Magnesium L-Threonate & Cognitive Improvements; Dose, Sleep

00:48:28 Acknowledgements

Disclaimer & Disclosures

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My guest is Dr. Jennifer Groh, PhD, professor of psychology and neuroscience at Duke University. She explains how our brain encodes sights and sounds and integrates them so we can navigate and understand the world around us. She explains what thoughts really are and how what you focus on determines your thoughts, not just in that moment but your future thoughts too. We discuss this in the context of how to improve your level of focus and happiness and how to complete tasks and task-switch more effectively. We also discuss how you can rewire the neural circuits that underlie your default patterns of thinking and attention.

Sponsors

AGZ by AG1: https://drinkagz.com/huberman

Lingo: https://hellolingo.com/huberman

Wealthfront*: https://wealthfront.com/huberman

Our Place: https://fromourplace.com/huberman

Helix Sleep: https://helixsleep.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

0:00 Jennifer Groh

3:41 Sounds & Vision, Sensory Integration; Dynamic Maps

7:42 Context & Mapping; Screens, Projection & Perception, Ventriloquists

13:52 Sound Localization

16:53 Sponsors: Lingo & Wealthfront

19:50 Hearing Loss & Sound Localization, Ear Folds

21:56 Unfamiliarity of Hearing Your Own Voice; Tool: Bone Conduction Headphones

26:16 Tool: Headphone Volume & Protecting Hearing

28:57 3D Sound, Sound Distance, Thunder, Earthquakes

37:24 Sound Integration; Sound Frequency & Distance, Warning Signals

44:36 Sponsors: AGZ by AG1 & Our Place

47:39 Music, Rhythm, Community & Emotion

57:00 Music, Military; Courtship; Evolution of Music & Language

1:02:37 Ears, Visual & Auditory Integration, Sound Localization

1:09:48 Evolution of Visual & Auditory Systems, Music; Brain Controlling Vision

1:15:17 Sponsor: Helix Sleep

1:16:45 Physical Space & Sounds; Cathedrals, Sound Delay

1:22:37 Music, Emotion & Community; Science & Admitting Weakness

1:27:01 Thinking & Sensory Simulations; Forming Thoughts

1:33:18 Attention, Attractor States, Flow States, Tool: Changing Environment

1:37:38 Sounds & Environment for Focus, Attention, Tool: Mental Interval Training

1:44:37 Sponsor: LMNT

1:45:58 Endurance & Interval Mental Work; Mental Rest, Music

1:50:37 Musician, Rehearsal & Performance; Pressure

1:54:16 Chickens; Hypnotizing Chickens, Visual Attention & Focus

2:03:47 Relaxation, Phones & Schools, Boredom, Social Media

2:12:48 Acknowledgements

2:13:58 Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Protocols Book, Social Media, Neural Network Newsletter

*This experience may not be representative of other Wealthfront clients, and there is no guarantee of future performance or success. Experiences will vary. The Cash Account, which is not a deposit account, is offered by Wealthfront Brokerage LLC, member FINRA/SIPC.  Wealthfront Brokerage is not a bank. The base APY is 3.50% on cash deposits as of November 07, 2025, is representative, subject to change, and requires no minimum. If eligible for the overall boosted rate of 4.15% offered in connection with this promo, your boosted rate is also subject to change if the base rate decreases during the 3 month promo period. Funds in the Cash Account are swept to program banks, where it earns the variable APY. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Investment advisory services are provided by Wealthfront Advisers LLC, an SEC-registered investment adviser. Securities investments: not bank deposits, bank-guaranteed or FDIC-insured, and may lose value.

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In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses.

I explain why successful fear treatment requires both extinction of the old fearful response and replacement with a new positive association—not just cognitive reframing. I also explain how the threat reflex activates specific circuits connecting the amygdala, prefrontal cortex, and dopamine systems, and why detailed recounting of traumatic events progressively reduces their physiological impact. Finally, I review evidence-based approaches, including prolonged exposure therapy and cognitive behavioral therapy, discuss how five minutes per day of deliberate stress through cyclic hyperventilation can rewire fear responses, explain the critical role of social connection in activating neural pathways that reduce trauma, and share supplementation options for managing anxiety.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

LMNT: https://drinklmnt.com/huberman

Function: https://functionhealth.com/huberman

Timestamps

(0:00) Introducing Fear & Trauma

(0:17) What is Fear?

(1:03) Autonomic Arousal: "Alertness" vs. "Calmness"

(2:05) Fear vs. Stress & Anxiety

(9:20) "The Threat Reflex": Neural Circuits for Fear

(20:50) Cognitive (Narrative) Therapies for Fear

(26:35) PTSD Treatments: Ketamine, MDMA, Oxytocin

(33:11) Deliberate Brief Stress Can Erase Fears & Trauma

(35:51) Nutrition, Sleep, & Other General Support Erasing Fear & Trauma

(38:18) Recap

Disclaimer & Disclosures

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My guest is Dr. David Fajgenbaum, MD, professor of translational medicine and human genetics at the University of Pennsylvania. He explains how, unbeknownst to most doctors, many approved medications can successfully treat or even cure diseases other than the ones they are typically used to treat. He shares his story of escaping death from Castleman's disease by discovering a life-saving treatment using repurposed drugs that were approved for other purposes. Our conversation explores how researchers, physicians, and you—the general public—can explore novel treatments and cures to conditions the medical profession has deemed untreatable, including cancers. We also discuss the crucial role of mindset in battling diseases and the lesser-known use of compounds to promote health and longevity.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Rorra: https://rorra.com/huberman

David: https://davidprotein.com/huberman

Function: https://functionhealth.com/huberman

Timestamps

(0:00) David Fajgenbaum

(4:06) Self-Agency in Healthcare; New Uses for Old Medicines

(6:44) Other Uses of Aspirin & Viagra; Drug Development & Approved Use

(8:53) Lidocaine & Breast Cancer; Pharmaceutical Companies & Incentives

(11:36) Sponsors: Eight Sleep & Rorra

(14:16) Pharmaceutical Companies, Patents & New Uses; Lithium

(18:40) Tools: Finding Reliable Health Sources, Asking Questions & Disease Organizations; DADA2 Treatment

(21:53) Medical Community & Connections; Integrated Medical Databases

(24:36) Drug Repurposing, Thalidomide, Pembrolizumab

(28:45) Medical Research Databases, Mapping Disease Connections

(33:51) Every Cure Database & Programs, Bachmann-Bupp Syndrome; Colchicine & Heart Disease

(37:57) Sponsors: AGZ by AG1 & David

(40:41) David’s Medical & Career Journey, Glioblastoma, Castleman Disease

(49:10) Autoimmune Disease, Driven Personality, Stress & Immune System

(52:52) Castleman Disease, Treatment, Chemotherapy

(55:54) Physician Continuing Education, Santa Claus Theory of Civilization; Science Collaboration

(1:03:32) Medical School, Relapse & “Overtime”, Finding a New Treatment, Rapamycin

(1:12:46) Sport, Football & Resilience; Challenge & Personal Growth, Family

(1:18:41) Sponsor: Function

(1:20:29) Social Support; “Overtime”, Gratitude

(1:23:19) Business School, Castleman Disease Treatment; Repurposing Drugs & AI

(1:28:29) Drug Repurposing, POEMS Syndrome; Mitigating Risk

(1:35:32) Nicotine, Compounds for Preventive Health; GLP-1 Agonists

(1:40:51) Bioprospecting, Drug Development; AI, Prioritization & Novel Connections

(1:46:18) Healthcare & Children; Hope, Action & Impact Circuit; Challenge & Super-Agers

(1:52:50) Get Involved with Every Cure

(1:56:20) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

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In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging.

We discuss the cellular and molecular mechanisms of aging—and how specific behaviors, such as fasting, regular exercise and NAD⁺-boosting compounds like NMN, can activate the body's natural longevity pathways. This discussion highlights how lifestyle choices profoundly influence the aging process and may even slow or reverse key aspects of biological aging.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

David: https://davidprotein.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Timestamps

(0:00) David Sinclair

(0:20) Longevity, Anti-Aging, Aging as a Disease

(2:27) Causes of Aging; Epigenome & Genes

(4:53) CD & Scratches Analogy, DNA, Silencing & Expressing Genes

(6:44) Physical Appearance & Aging

(7:36) Sponsor: David

(8:54) Childhood Development & Aging, Horvath Clock, Accelerate Aging

(11:30) Rates of Puberty & Aging, Growth Hormone

(12:37) Body Size & Longevity; Epigenetics

(13:07) Fasting, Calorie Restriction & Longevity, Sirtuins, Insulin & Glucose

(16:31) Tool: Skip a Meal

(17:07) Longer Fasts & Autophagy, “Deep Cleanse”

(18:07) Sponsor: AGZ by AG1

(19:36) Fasting, Fluids, Electrolytes

(20:16) Sirtuins, Glucose, mTOR & Fasting; Leucine, Tool: Pulsing Behaviors

(24:24) Breaking a Fast, Tools: Do Your Best; Transitions

(27:00) Sirtuins, NAD, NMN Supplementation

(29:04) Sponsor: Eight Sleep

(31:10) Iron & Senescent Cells; Personalize Medicine

(32:40) Tool: Blood Markers, CRP

(34:50) Tool: Aerobic & Resistance Exercise

(35:55) Estrogen, Fasting & Fertility; Aging & Rejuvenation

(38:20) Acknowledgements

Disclaimer & Disclosures

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Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat infections. I provide science-based tools that support your lymphatic system for the sake of health and appearance, including: how to reduce fluid retention in your limbs, trunk or face, how to eliminate 'bags' under your eyes and brain fog, and how to improve cardiac health and longevity. Because your lymphatic system lacks a central pump, it needs the mechanical forces generated by specific types of bodily movement, breathing and pressure to circulate your lymph properly, and I explain how you can activate these. I also explain how to support optimal functioning of your glymphatic system, a brain- and spinal cord waste-clearing system active during sleep that is crucial for brain functioning and longevity, including to prevent dementia.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

LMNT: https://drinklmnt.com/huberman

David: https://davidprotein.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Function: https://functionhealth.com/huberman

Timestamps

(00:00:00) Lymphatic System

(00:04:11) Circulatory System, Heart; Oxygen, Nutrient & Waste Transfer

(00:11:03) Lymphatic System, Fluid, Lymphedema, Chronic Inflammation; Brain Fog

(00:14:52) Sponsor: LMNT & David Protein

(00:17:28) Lymphatic Vessels, Tool: Enhance Lymphatic Drainage with Movement

(00:26:24) Tools: Jumping (Rebounding), Treading Water, Swimming

(00:27:41) Tool: Swelling, Lymphatic Drainage & Diaphragmatic Breathing

(00:32:05) Swimming & Lymphatic Flow; Tai Chi

(00:34:00) Lymphatic Massage, Cancer & Lymphedema; Jade Roller & Gua Sha

(00:37:28) Sponsor: AGZ by AG1

(00:38:56) Lymph Flow, Tool: Lymphatic Massage & Manual Lymphatic Drainage

(00:45:02) Immune Function of Lymphatic System, Sore Lymph Nodes

(00:54:24) Cancer Treatment, Lymph Nodes & Lymphedema

(00:57:02) Limb Swelling, Minor Lymphedema & Inflammation, Lymphatic Boots

(01:00:09) Sponsors: Eight Sleep

(01:01:43) Glymphatic System, Brain & Sleep

(01:05:56) Sleep & Brain Waste Recycling; Discovery of the Glymphatic System

(01:12:24) Enhance Glymphatic Clearance, Brain Fog, Age, Tool: Side Sleeping Position

(01:15:54) Tools: Optimize Sleep, Cardiovascular Exercise, Elevate Feet, Pillow

(01:17:29) Puffy Face, Tool: Lymphatic & Facial Massage

(01:21:23) Sponsor: Function

(01:23:11) Tool: Hydration & Lymphatic Support

(01:24:48) Tool: Cardiovascular Exercise & Lymphatic Vessels, Heart, Aging

(01:31:06) Tool: Infrared & Red Light, Mitochondria, Lymphedema, Skin Appearance

(01:36:08) Key Takeaways

(01:37:21) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice.

I explain why common gratitude practices (like simply listing things you're grateful for) are far less impactful than engaging in story-based gratitude practices. I also explain how being grateful activates specific brain regions, which enhance calm, social connection and motivation, while reducing anxiety and inflammation. Finally, I share why we can't simply trick our brains into feeling grateful and describe a practical weekly gratitude practice that will improve both your mental and physical well-being.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

Eight Sleep: https://eightsleep.com/huberman

Our Place: https://fromourplace.com/huberman

Timestamps

(0:00) Gratitude

(0:30) Gratitude Practice Benefits

(3:22) Pro-Social vs Defensive Behaviors, Gratitude

(6:25) Sponsor: Eight Sleep

(8:07) Serotonin, Brain & Context, Gratitude Mindset

(14:02) Context, Can You Lie to Yourself?

(14:48) Effective Gratitude Practice, Tools: Receiving Gratitude, Story

(21:18) Sponsor: AGZ by AG1

(22:47) Tool: Find & Revisit Inspirational Stories

(27:30) Heartfelt Intention, Genuine Thanks

(29:42) Sponsor: Our Place

(31:03) Gratitude Practice Benefits for Anxiety, Fear & Motivation

(33:29) Gratitude Practice Benefits for Immune System

(36:02) Recap: Establishing an Effective Gratitude Practice

Disclaimer & Disclosures

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My guest is Steven Pressfield, author of The War of Art and expert in how to overcome the inner force of "resistance"—the self-sabotaging tendency to procrastinate on your life's most important work that keeps you from realizing your professional and creative potential. Steven shares actionable tools for defeating inner resistance that work. His approach is concrete, not based on slogans or inspirational messages. As the author of numerous best-selling books and screenplays, Steven's routines for cultivating discipline and focus, including his physical training regimen (he is incredibly mentally and physically vigorous at 82), are applicable by anyone. He gives you effective practical strategies for how to structure your day, overcome procrastination and self-doubt and do your best, most meaningful work.

Read the episode show notes at hubermanlab.com.

Thank you to our sponsors

AGZ by AG1: https://drinkagz.com/huberman

Helix Sleep: https://helixsleep.com/huberman

BetterHelp: https://betterhelp.com/huberman

Rorra: https://rorra.com/huberman

Function: https://functionhealth.com/huberman

David: https://davidprotein.com/huberman

Timestamps

(00:00:00) Steven Pressfield

(00:04:55) Ideas & Resistance, Tree & Shadow Analogy

(00:08:45) Military, Pushing Through Resistance, War of Art

(00:10:14) Physical Training, Tools: Capturing Ideas, Little Successes

(00:16:11) Sponsors: Helix Sleep & BetterHelp

(00:18:36) Ideas, Invocation of the Muse, Goddess

(00:23:19) Writing, Focus, Inner Critic, Perfectionism, Tool: Think in Multiple Drafts

(00:28:21) Writing Session; Workout Analogy & Concentration

(00:32:28) Aspiring Writers & Focused Hours; Work Session Timing; Phones

(00:35:31) Inner Voice; Storytelling, Advertising

(00:39:45) Soul & Growth, Creativity, Your Calling & Voices of Resistance, Suppression

(00:48:10) Loved Ones: Projection, Resistance & Sabotage

(00:51:04) Sponsors: AGZ by AG1 & Rorra

(00:53:52) Angry & Numbing Out, Resistance, Internet; Following Your Calling

(00:59:00) Mentors: Lessons on Focus & Quitting

(01:06:46) Perfectionism

(01:10:42) Contemplating Your Mortality, Family Honor

(01:16:49) Proving Yourself & Competition

(01:22:01) First Movie, Failure, Analyze Feedback?, Tool: Self-Evaluation

(01:28:28) Book Success, One-Hit Wonders; Book Titles

(01:34:22) Sponsor: Function

(01:36:09) Personal Sacrifice; High Achievers & Unbalanced Life; Social Media

(01:44:44) Tool: Turning Pro, Amateur vs Professional Habits, Failure, Feelings

(01:49:32) Cost of Turning Pro, Tool: Taking Oneself Seriously & Others’ Reactions

(01:56:42) Creativity: Practical Advice & Muse; Acts of Faith; Surrender

(02:04:00) Sponsor: David

(02:05:17) Workspace, Uncomfortable Chair, Physical Labor, Complaining

(02:08:13) Forthcoming Book, Book Recommendations

(02:13:46) Zero-Cost Support, YouTube, Spotify & Apple Follow, Reviews & Feedback, Sponsors, Protocols Book, Social Media, Neural Network Newsletter

Disclaimer & Disclosures

Learn more about your ad choices. Visit megaphone.fm/adchoices

In this Huberman Lab Essentials episode, my guest is Dr. David Berson, PhD, a professor of neuroscience at Brown University and an expert on the visual system and circadian biology.

We explore how the brain processes visual information, from photons entering the eye to conscious perception in the cortex. We discuss color vision, the discovery of melanopsin and intrinsically photosensitive retinal ganglion cells, and how light regulates our circadian clock and melatonin release. We also examine the vestibular system's role in balance and motion detection, the cerebellum's function in motor coordination, and the midbrain's integration of multiple sensory inputs. Finally, we discuss the basal ganglia's role in decision-making and an extraordinary case of neuroplasticity in visual cortex.

Read the episode show notes at hubermanlab.com.

More Huberman Lab Essentials: https://hubermanlab.com/essentials

Thank you to our sponsors

AGZ: https://drinkagz.com/huberman

Function: https://functionhealth.com/huberman

LMNT: https://drinklmnt.com/huberman

Timestamps

(00:00:00) Dr. David Berson

(00:00:30) Visual Perception, Photons & Retinal Processing, Ganglion Cells

(00:02:12) Color Vision, Wavelengths & Photoreceptors; Cones & Rods

(00:05:56) Sponsor: AGZ by AG1

(00:07:24) Melanopsin, Intrinsically Photosensitive Retinal Ganglion Cells & Brightness Detection

(00:08:31) Circadian Clock & Synchronization, Suprachiasmatic Nucleus (SCN); Master Clock Function

(00:11:16) Hypothalamus, Autonomic Nervous System & Hormonal Systems

(00:13:01) Tool: Light Exposure & Melatonin Regulation, Pineal Function

(00:14:35) Vestibular System, Balance & Motion Detection; Semicircular Canals

(00:16:44) Vestibulo-Ocular Reflex, Image Stabilization & Head Rotation

(00:18:51) Sponsor: Function

(00:20:45) Motion Sickness, Visual-Vestibular Conflict; Tool: Avoiding Nausea

(00:22:24) Cerebellum, Motor Coordination & Learning

(00:23:17) Cerebellar Function, Precision & Timing of Movement; Cerebellar Ataxia

(00:24:54) Flocculus & Visual-Vestibular Integration

(00:25:56) Midbrain, Brainstem & Reflexive Behavior; Superior Colliculus

(00:28:26) Spatial Orientation & Multisensory Integration; Rattlesnake Heat Detection

(00:30:13) Sensory Integration & Corroboration

(00:31:13) Sponsor: LMNT

(00:32:45) Basal Ganglia, Go vs No-Go Behavior & Decision Making

(00:33:56) Tool: Impulse Control & Delayed Gratification, Marshmallow Test

(00:34:51) Individual Differences, Genetics & Experience

(00:35:37) Visual Cortex, Neural Processing & Brain Plasticity

(00:36:26) Cortical Reorganization, Braille Reading & Stroke Recovery

(00:39:15) David Berson's Work; Acknowledgements

Disclaimer & Disclosures

Learn more about your ad choices. Visit megaphone.fm/adchoices