Dr. Rhonda Patrick is a renowned scientist, researcher, and the founder of FoundMyFitness.

This conversation explores how exercise enhances brain function—upending old beliefs about lactate—while examining new research on microplastics’ accumulation in our bodies and practical ways to protect ourselves.

In the process, Rhonda helps me understand my own relationship with exercise intensity and chronic exposure to environmental toxins.

As always, Rhonda provides fascinating insights along with practical wisdom. Enjoy!

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Vice Admiral Dr. Vivek Murthy is America’s Surgeon General, a visionary public health leader, and architect of groundbreaking initiatives addressing loneliness and youth mental health.

This conversation—likely his final interview in office—reveals how disconnection underlies our growing health challenges. We explore the parental mental health crisis, the impact of social media on youth, and his powerful parting prescription for America: choose community. While his recent landmark advisory on alcohol warning labels came after our recording, we delve into his vision for healing by rebuilding connection.

Dr. Murthy offers us medicine for what ails us. This one is special. Enjoy!

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Peter Diamandis is a renowned physician, futurist, and the founder of XPRIZE, whose paradigm-shifting work transforms our understanding of aging and human potential.

This conversation delves into the duality of our longevity revolution: the simple, actionable tools accessible to anyone today, and the bold technologies that could reshape our future. From innovative diagnostics to organ regeneration, Peter details why this decade might fundamentally alter our relationship with aging.

Along the way, we examine practical health strategies and the philosophical implications of extending human healthspan.

Peter is the ultimate optimist. Enjoy!

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Mark Manson is a renowned author and cultural critic, known for “The Subtle Art of Not Giving a F*ck”—a global phenomenon that has remained on the NYT bestseller list for an unprecedented 328 weeks.

This conversation explores the paradox between genuine growth and modern self-help culture. We discuss Mark’s dramatic transformation, his contrarian views on personal development, why being intelligent often hinders change, and how the most effective solutions in life are typically the boring ones no one wants to hear about.

In today’s metrics-driven landscape, he reveals how to navigate content creation with integrity.

Mark is endlessly insightful. This one is profound and irreverently fun. Enjoy!

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In this concluding chapter of our “Best Of” 2024 series, we share wisdom from an extraordinary group of changemakers who challenged our assumptions and expanded our possibilities.

From a septuagenarian fitness icon to Spider-Man himself, from free solo climbers to modern mystics—each guest illuminated different facets of human potential. Their stories of courage, creativity, and conscious living remind us that transformation is always possible.

I’m deeply grateful to our guests for their vulnerability, to my team for their dedication, and to our sponsors for their continued support.

But most of all, I’m grateful for you, the listener. Your willingness to grow and transform alongside us makes this journey meaningful.

Thank you for sharing another remarkable year. Here’s to an extraordinary 2025.

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We are here to grow. We are here to transform. This is our birthright. This is our purpose.

As the year ends, I want to honor this truth by sharing insights from some of the most remarkable voices who joined us in 2024. In this first of our two-part Best Of series, we revisit conversations that challenged and inspired us to reach higher.

From stories of survival and rebirth, to breakthroughs in longevity science and brain health, to raw conversations about athletics and consciousness—each guest illuminated different paths to living authentically and purposefully.

I’m deeply grateful to our guests for their candor, to my team for their dedication, and to our sponsors for their continued support.

But most of all, I’m grateful for you, the listener. Your presence and engagement make this journey worthwhile. I never take that for granted.

Thank you for growing with us. Here’s to an extraordinary 2025.

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Dr. Rangan Chatterjee is a renowned physician, one of Britain’s most influential medical voices, and author of the new book, “Make Change That Lasts.”

This conversation explores the intersection of neuroscience and human potential as it introduces his groundbreaking concept of “minimal reliance.” Dr. Chatterjee deconstructs why we remain tethered to patterns that no longer serve us, while offering actionable tools for lasting change.

Don’t miss this conversation—it might transform your thoughts about personal evolution.

Enjoy!

Note: As a special bonus, we’re giving away a Dr. Chatterjee Book Bundle. Subscribe to the newsletter at richroll.com/subscribe for a chance to win.

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Harley Finkelstein is Shopify’s President and an entrepreneur who started his first company at 13.

This conversation explores the intersection of commerce and personal growth through Harley’s iconoclastic lens. We discuss democratizing entrepreneurship, the role of anxiety as fuel for achievement, and why this might be the most generative moment in history to start a business.

Harley challenges my self-perception as an entrepreneur, forcing me to untether from limiting beliefs about what it means to build something meaningful.

Sharp, vulnerable, and endlessly optimistic—this exchange offers a fresh take on modern entrepreneurship. Enjoy!

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Josh Szeps is a renowned broadcaster, host of Uncomfortable Conversations, and a former voice of Australia’s public radio who brings discernment to our most difficult dialogues.

This conversation explores why genuine dialogue matters in an age of tribal certainties. We discuss the derangement of our information landscape, the erosion of shared truth, and how to navigate today’s most contentious issues with grace and humor.

Josh is a rare voice who can untangle complex issues without amplifying division. Our exchange is both timely and necessary. Enjoy!

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Dr. Charan Ranganath is a prominent neuroscientist, a professor at UC Davis, and the author of the influential book “Why We Remember.” 

This conversation explores the profound intersection of neuroscience and human experience. Charan reveals that our most resonant memories resemble paintings more than photographs, continuously reshaped by the present moment. We discuss the role of memory in identity, survival, and healing, as well as its implications in our digital age. 

During our exchange, I gained insight into why my cherished memories might be less reliable than I had previously believed. 

Charan is an impressive yet approachable voice in memory science. This exploration might make you question your narrative. Enjoy!

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