In the April 25th edition of biobytes, Holger Richly (Institute of

Molecular Biology, Mainz, Germany) describes how ZRF1 remodels E3 ubiquitin ligases

at DNA lesion sites (Gracheva et

al.) and Kenneth Pryde (University College London, London, England, UK,

and University of Cologne, Cologne, Germany) explains how PINK1 induces the

fragmentation of damaged mitochondria (Pryde et

al.). Plus a roundup of other highlights from The Journal of

Cell Biology. The show was written and produced by Caitlin Sedwick and

Ben Short. Presented by Ben Short. See the associated papers in

JCB for details on the funding provided to support these

original research studies.