In the April 25th edition of biobytes, Holger Richly (Institute of
Molecular Biology, Mainz, Germany) describes how ZRF1 remodels E3 ubiquitin ligases
at DNA lesion sites (Gracheva et
al.) and Kenneth Pryde (University College London, London, England, UK,
and University of Cologne, Cologne, Germany) explains how PINK1 induces the
fragmentation of damaged mitochondria (Pryde et
al.). Plus a roundup of other highlights from The Journal of
Cell Biology. The show was written and produced by Caitlin Sedwick and
Ben Short. Presented by Ben Short. See the associated papers in
JCB for details on the funding provided to support these
original research studies.