In the August 15th edition of biobytes, Mark Philips (New York

University School of Medicine, New York, NY) describes how N-Ras is transferred

between membrane compartments (Zhou et

al.) and Pete Cullen (University of Bristol, Bristol, England, UK)

explains how disease-causing mutations affect the retromer complex's function

in endosomal trafficking (McMillan et

al.). Plus a round-up of other highlights from The Journal of

Cell Biology. The show was written and produced by Caitlin Sedwick and

Ben Short. Presented by Ben Short. See the associated papers in

JCB for details on the funding provided to support these

original research studies.