In the September 14th edition of biobytes, Patrick Caswell (University

of Manchester, Manchester, UK) describes how actin spikes drive 3D cell migration

(Paul

et al.) and Benoît Kornmann (ETH Zurich, Zurich, Switzerland)

explains how defects in ER–mitochondrial contacts can be bypassed by other

organelle contact sites (Lang et

al.). Plus a round-up of other highlights from The Journal of

Cell Biology. The show was written and produced by Caitlin Sedwick and

Ben Short. Presented by Ben Short. See the associated papers in

JCB for details on the funding provided to support these

original research studies.