BioPOD

How did this Edinburgh Professor move from studying physics to starting a Biotechnology spin-out company? In our new episode, we hear from Professor Teuta Pilizota all about how her past research experiences led her to where she is today, how her research keeps leading her to new technological developments and how this culminated in her starting a biotech spin-out company.  

Many researchers spent a significant amount of time cultivating microorganisms, so they reach the desired growth phase and density. But what if that whole process could be automated, monitored and measured? This is where the OGI Bio Bioreactor comes in, to save time and allow specifications of culture conditions. 

Find out more about OGI Bio here: https://ogibio.co.uk/ 

Interview & artwork by Liz Gaberdiel, intro & editing by Ruby White.

Why do you think you are awake right now? You might be aware that your circadian rhythm determines your sleep cycle. But how does your body keep time? Can a cell have a clock? And how can this system survive perturbations?

Gerben van Ooijen and his lab @vanOoijenLab work on finding out some of the cellular mechanisms that are behind the ability of an organism to keep time. They study modified algae that give off light during some phases of the circadian clock, to shine some light on the particularities of time-regulated genes.  We also find out how circadian dysregulation could have an impact in cancer.

In this episode, Apple Chew chats to Professor Gary Loake, a group leader at the Institute of Molecular Plant Sciences at the University of Edinburgh. His group researches the immune responses of plants.

Gary is also the founder and chief scientific officer of the biotech startup Green Bioactives. Since plants can produce immune-related products with sometimes useful properties and up to 25% of pharmaceuticals trace back to plant natural products, his company develops a biomanufacturing platform to efficiently churn out valuable products.

Check out Green Bioactives here: https://www.green-bioactives.com/ 

Where do plant scientists get their plant materials from? How do you best grow a new species? In this episode, Haomiao sits down with Dr Sophie Haupt, the manager of the plant growth facility at the University of Edinburgh. As part of the facility team, she supports research and teaching projects by growing all kind of plants in grow domes, glass houses, and of course outside.  

Sophie is also working on a conservation project on campus, to provide a safe and biodiverse habitat for native wildlife such as hedgehogs to return to campus. As part of this project, they have even planted some berry bushes and have started a little vegetable garden. 

In this episode, Liz Gaberdiel chats to Gerben van Ooijen, postgraduate advisor and Director of the Graduate School at the University of Edinburgh. They discuss the role of postgraduate advisors and how they can help during PhD studies. We hear what situations postgraduate advisors can help with and Gerben gives us some vital advice on how to maintain a productive, healthy and enjoyable PhD journey.  They also discuss his work as the Director of the Graduate Schoo and illustrate the key role he plays in maintaining the high standards of Edinburgh's PhD programmes. 

In this episode Liz Gaberdiel interviews Karen Woodcock and Mairead Rae, the Postgraduate Programme Administrators of ICB, IQB3 and IEB, IIIR, IMPS, respectively, in the School of Biological Science at the University of Edinburgh. They share their experiences working with postgraduate students, what insights they accumulated from that work and share top tips on a successful PhD. They also introduce a wide range of support they can provide and share useful resources for a successful PhD. 

Visit and bookmark Institue of Academic Development website https://www.ed.ac.uk/institute-academic-development  

Get in touch by email with Karen [email protected] or Mairead [email protected].  

Also, you can now drop by their office at Mary Brück Building from Monday-Thursday and alternate Fridays (at the time of the recording, restrictions on in person meetings were in place). 

Fossil fuels are used everywhere, in our clothing, our medicine, and even our cooking. Wouldn’t it be great if we could use another source to synthesise these necessary molecules. Maybe something that’s very abundant and unwanted, such as waste streams from other processes?  

In this episode, we’re diving into how microorganisms could be useful in synthesising biomaterials. Even better, they can be used to clean up waste products and turn them into something useful. Severina Pociunaite sits down with Dr Stephen Wallace to discuss his work and his goals for a sustainable future. 

Check out some of the research mentioned by Stephen here: https://wallacelab.bio.ed.ac.uk/publications-1 

And keep an eye out for his TED Talk from this year’s TEDxVienna. 

Right on the heels of the 2022 World Antimicrobial Awareness Week, this episode covers a broad overview of the key topics associated with antimicrobial resistance. Rose Doyle from BioPOD teamed up with Carys Redman-White from the new Edinburgh antimicrobial resistance podcast EdiAMR to chat to Dr Brian Wee about his work. We hear his thoughts on the best tools and tactics to combat the rise of antibiotic resistance as well as a deep dive into one decade-long research project about the spread of antibiotic resistance in Kenya. Art by Annis Newman, intro and editing by Severina Pociunaite.

If you want to learn more about Brian’s work on whole genome sequencing across Nairobi, check out his paper here: https://www.nature.com/articles/s41564-022-01079-y 

This episode is a collaboration between BioPOD and the University of Edinburgh's new antimicrobial resistance podcast, EdiAMR. If you’re interested to find out more about AMR, follow @EdiAMR on twitter for updates! 

In this very special episode, we hear from Dev, Charity, and Diana, who are part of a team competing in this years’ iGEM (International Genetically Engineered Machine) competition. Students from the University of Edinburgh and from the University of Health and Allied Services in Ghana joined forces to develop synthetic biology projects to solve local problems. The local problem they want to tackle? Heavy metal and plastic pollution in water bodies. Detecting pollution in rural areas can be difficult, so the team was working on a cell-free biosensor that can detect a variety of dangerous metals. To then remediate the problem, they designed a cellulose hydrogel to “mop-up” contaminants in water. Additionally, they address plastic pollution by investigating an enzyme cocktail for biodegradation of PET plastic. We also hear about what they learned during the competition and how they enjoyed being part of an international collaboration. 

iGEM wiki: https://2022.igem.wiki/edinburgh-uhas-ghana/index.html 
IDEC: https://idec.io/index.html

In this episode, Chris Donohoe (@dono_heptane) chats with PhD students Casey Patmore (@paseycatmore) and Georgia Lambert (@GALambert3) about the fascinating world of the behavioural ecology of burying beetles. They discuss how to "keep calm and carrion" when researching beetles, who need carrion to raise their progeny. What factors affect their parenting behaviour and what can it teach us about the complex responses of insects to effectively care for their offspring?