BioTA Podcast

From racehorses to fancy pigeons, Darwin saw selective breeding as humans applying one of nature’s most powerful forces, evolution by natural selection, to change domesticated species. This episode explores how Darwin used evidence of what he called artificial selection to support his ideas on natural selection and evolution, how modern genetics backs him up, and why selection is constantly shaping the world around us.

In this Twilight Zone-inspired episode of BioTA, two biology students prepping for lab encounter a pair of unexpected space travelers who want help unraveling a mystery: Why do some bacteria defy antibiotics while others perish? Why do some plants tolerate herbicides while others shrivel? With a crash course in the concepts of genotypes and phenotypes, the students explain some of the basic principles that life on Earth follows (most of the time). 

This episode uses the sci-fi action film Jurassic Park as a springboard to explore fundamental concepts in genetics. While the film imagines resurrecting dinosaurs through ancient DNA, we break down the real science behind this film, clarifying what a genome is, how chromosomes organize DNA, and how genes function as trait-coding units with alleles as their variations. By separating cinematic fiction from reality, we can learn some genetics while uncovering what’s scientifically possible, and what is purely Hollywood fantasy.

Once a global scourge, smallpox devastated millions before Edward Jenner’s vaccine offered hope. But how do you deliver a life-saving cure to the farthest reaches of the world? In 1803, Spain launched the Balmis Expedition, a bold and ethically fraught mission to transport the vaccine across oceans. In this episode, we explore the science of viruses, vaccines, and immunity, while uncovering the surprising and unsettling story of La Real Expedición Filantrópica de la Vacuna.

CRIPSR-Cas9 technology allows scientists to edit genes with precision. But is this a beneficial tool or something more nefarious? In this episode, we conclude our conversation with Dr. Rodolphe Barrangou, one of the scientists who discovered CRISPR, and dive into the applications, ethical conundrums, and challenges of this new genetic tool. He also issues a challenge to all scientists about our responsibilities to share our work with the rest of the world.

CRISPR-Cas9 gene editing technology is one of the newest and most promising tools in science. But what is it? How does it work? And what are scientists doing with this technology that has been described as a molecular genetic scalpel? In this first of two episodes, we talk with Dr. Rodolphe Barrangou, the first scientist to discover and publish results demonstrating what the CRISPR-Cas9 system can do, thereby opening the door for other scientists and discoveries.

While the terms citizen science and community science emerged and began gaining broad attention in the 1990s, the collaboration between scientists and the public has a rich history spanning over a century. Today, numerous citizen science projects covering a wide range of topics invite public participation. Innovative educators are now involving students to enhance STEM education and foster new forms of community engagement. Join us in this episode as we speak with experts to learn about citizen science and its transformative potential in communities, education, and beyond!

Apples are a household favorite, but have you ever wondered why some varieties are common, but others are rare, coveted heirlooms? Or thought about the epic journey that brought apples from their birthplace in Central Asia to orchards spanning the globe or maybe your own yard? And why don’t we grow apple trees from seeds? We were curious too, which led us to invite Dr. Lisa Corwin and Amy Dunbar-Wallace onto BioTA to describe the thrilling story and science behind the Boulder Apple Tree Project, a citizen science initiative dedicated to discovering and safeguarding rare apple cultivars and preserving a living history of this beloved fruit.

What can an ancient bison skull tell us about human history? In this episode we talk with Dr. Leland Bement, an archaeologist from the Oklahoma Archaeological Survey who helped in discovering the oldest intentionally painted artefact ever found in the US. Using techniques that included standard archaeological practices as well as interdisciplinary collaborations, Bement’s team was not only able to figure out the story of the Cooper Bison Skull, but they also got a window into the past to learn more about the Folsom people who painted it. 

What does brushing your teeth have to do with the search for extraterrestrial life? To answer that question, you have to shrink down and explore the microscopic world of bacterial biofilms. In this episode three microbiologists will guide us through the world of these fascinating microbial communities by looking at what they are, how they impact our health, and how they may be similar to the life we are looking for in outer space.