We talk a lot about "data-driven healthcare," yet we're still blind to one of the most important data layers: the microbiome.

Mental health, early-onset cancer, autoimmunity—much of that risk is already visible in the gut years before a diagnosis code ever hits the chart. Most care models, benefits designs, and longevity strategies simply don't account for it.

In this episode of Boombostic Health, I sit down with Paul Denslow, CEO & co-founder of Intus Bio, to dig into how GutID turns the microbiome into hard infrastructure: high-resolution gut data, a score you can track, and a way to see whether your interventions are actually moving risk—not just spend.

In this episode, we cover:

• Why microbiome disruption often precedes mental health issues and cancer

• How GutID converts millions of bacterial data points into a single, trackable gut score

• Why behavioral health and functional practitioners have been early adopters

• The problem with "just take a probiotic" in the absence of baseline gut data

• How AI + high-resolution microbiome testing open a real prevention window

• What a serious prevention and longevity strategy looks like when gut data is included

If you're responsible for care delivery, benefits strategy, or long-term risk, ignoring this data layer is no longer a neutral decision.

Watch the full conversation to see why mental health, cancer, and your "bacterial you" belong at the center of modern prevention.

About our guest:

Paul Denslow is the CEO and co-founder of Intus Bio, the company behind GutID. With a background in finance and big data, Paul partnered with co-founder Mark Driscoll, a pioneer in next-generation sequencing, to build a platform that treats the microbiome as a hard data problem—not a mystery. Intus Bio's GutID test and Titan 1 platform are used by clinicians and practitioners to generate high-resolution microbiome data that can be translated into actionable prevention and disease insights.

Links & Resources:

Learn more about GutID: https://www.gutid.com/collections/all

Learn more about Intus Bio: https://www.intusbio.com/gutid

Watch more Boombostic Health episodes: https://www.boombostichealth.com/podcast

Virtual care is scaling. AI is everywhere. But when lab completion falls from ~70% in-clinic to ~30% in virtual care, the whole model breaks. Virtual Care Without Labs Is Just Zoom - Even with AI. In this Boombostic Health in the Wild episode from HLTH 2025, Bradley Bostic sits down with Maitham Dib, founder of Junction, to unpack the "real" bottleneck: turning lab orders into lab results. They dig into how Junction: * White-labels lab infrastructure so any virtual or hybrid care model can deploy labs across all 50 states * Uses data from ~3.4 million lab tests annually to model what actually drives lab completion * Dynamically routes patients across PSC visits, at-home kits, and at-home phlebotomy - based on real-world behavior * Plugs into telehealth and AI agents that still need working diagnostic rails to be useful Chapters 00:00 – Lab in the basement, but core to care 02:00 – 70% in-clinic vs. ~30% virtual: the lab completion cliff 03:30 – Junction's white-label "Amazon-style" lab experience 06:30 – Three modalities: PSC, at-home kits, at-home phlebotomy 08:20 – "Where is the software actually?" Models on 3.4M lab tests 09:40 – Doctors, AI agents, and the diagnostic infrastructure layer 11:00 – Telehealth, pharma, and diagnostics as a new access door 12:40 – Business model: a new cost in a system that hates new costs Key Takeaways * Virtual care without completed labs is just Zoom. When fulfillment drops from ~70% in-clinic to ~30% in virtual, diagnosis and revenue leak out. * The real AI bottleneck is diagnostics.Agents and navigation tools only work if they can talk to lab infrastructure that actually gets tests done. * Infrastructure beats slogans.White-labeled, data-driven lab rails that convert orders to results are where virtual care and AI either succeed—or quietly fail. #boombostichealth #virtualcare #telehealth #digitalhealth #digitalhealthcare #healthcareinnovation #aiinhealthcare #patientcare #valuebasedcare #healthcare

Virtual care isn't a feature. It's the future care model nobody in healthcare wants to admit is already here.

At HLTH 2025, we sat down with Michael Dalton, CEO and founder of Ovatient, to unpack the real story behind why rural and urban patients alike are falling through the cracks and how Ovatient built the first truly integrated virtual multi-specialty practice on Epic.

This conversation exposes three uncomfortable truths in healthcare:

1. Access is still broken. Millions delay care because transportation, work schedules, stigma, or geography get in the way.

2. Telemedicine wasn't enough. Single-visit, transactional virtual care doesn't build trusted relationships, close care gaps, or keep patients inside a system of care.

3. Health systems are missing billions in preventable leakage. Ovatient's "digital health home" model quietly fixes that.

Dalton breaks down why: • A virtual-first care model that's integrated directly into Epic makes specialists accessible within hours, not months • 95% of patients can be supported at home while still remaining inside their health system • Weight management, behavioral health, primary care, and specialty care all operate seamlessly across one unified patient journey • Virtual care isn't cannibalizing brick-and-mortar — it's expanding the funnel

If you care about access, equity, referral management, or the economics of keeping patients connected to a system of care… this episode will challenge everything you think you know about "telemedicine."

Ovatient isn't building a digital front door. They're building the digital health home. And it's changing the game.

🎧 Listen now and rethink everything you thought "virtual care" meant.

Chapters

00:00 Introduction to Ovatient and Its Purpose

01:49 The Virtual Multi-Specialty Care Model

05:36 Integration with Health Systems

09:19 Building Trust in Healthcare

12:29 Closing Care Gaps with E-Consults

AI will accelerate healthcare — but genomics will rewrite it. The minute DNA drives care decisions for everyone, the current system becomes obsolete.

Gene by Gene quietly runs one of the most advanced, high-throughput genomics labs in the world — powering platforms like MyHeritage and rapidly transforming clinical medicine, oncology, pharmacogenomics, and ancestry.

This conversation explores what happens when every person leaves the hospital with a genomic passport — a lifelong DNA profile they own, control, and use to prevent disease before it begins. This is preventive medicine at scale. Not someday — now.

What You'll Learn

- Why the genomics industry just flipped overnight

- How AI + sequencing will routinely identify disease risk decades early

- What happens when every patient controls their genomic data

- How pharmacogenomics improves medication safety and outcomes

- Why the healthcare system can't keep up with genomic progress

Chapters

00:00 – Live at HLTH 2025 00:29 – The quiet giant behind global genomics

01:20 – From physician to entrepreneur

02:45 – Acquiring Gene by Gene

04:19 – The massive shift to whole-genome sequencing

05:59 – Why more data = better diagnosis and prevention

07:30 – DecisionRx partnership and real-world outcomes

08:19 – Cost, speed, and modularity as the winning edge

09:52 – Sequencing every newborn at birth

11:00 – Data democratization and genomic ownership

11:59 – AI + 3 billion base pairs: why machines must lead

13:24 – Polygenic risk scoring and preventive cardiology

15:38 – Cognitive health and early-intervention models

16:40 – Nutrition + genomics: personal story

17:50 – Sleep, diet & medication metabolism

18:25 – Closing thoughts and future collaboration

Learn more:

https://www.boombostichealth.com/

https://www.genebygene.com/

#genomics #precisionmedicine #boombostichealth #DNARevolution #healthcareinnovation #futureofhealthcare #preventivemedicine #healthtech #biotechnology #artificialintelligence

Pharma Isn't Broken — Access Is

ixlayer x Sanofi Ventures @ HLTH 2025 Patients don't suffer because we lack medical innovation — they suffer because it takes too long to access it.

🚀 Why This Matters Patients today are consumers — they expect speed, personalization, and access. Pharma, technology, and venture capital are aligning to deliver it.

The future of healthcare is collaborative, data-driven, and patient-first. Live from HLTH 2025 in the Diagnostic Zone, we dig into the real barriers between patients and lifesaving therapies. This episode covers:

• How digital platforms reduce barriers to treatment
• How AI is fueling proactive, personalized care
• Why strategic capital accelerates patient-impact innovation

Featuring: Pouria Sanae — Co-Founder & CEO, ixlayer Cris De Luca — Sanofi Ventures ⏱️

Timestamps

00:00 — Live at HLTH: Rethinking the pharma-patient connection

02:18 — Why patient access is the real bottleneck

04:20 — Sanofi Ventures: inside the strategic innovation model

06:45 — The truth about time-to-treatment in America

08:40 — The evolution of ixlayer & diagnostics infrastructure

10:30 — Can big pharma really go patient-first?

12:00 — Evidence, outcomes & trust in AI + health tech

Listen & Subscribe Never miss an episode where we challenge the status quo in healthcare and spotlight the innovators building what's next.

Healing Healthcare™ starts with bold ideas — and the courage to build them.

#healthcareinnovation #digitalhealth #patientaccess #boombostichealth #aiinhealthcare #healthtech #pharmainnovation #futureofhealthcare #hlth2025 #hlthusa #PrecisionMedicine

Prescription costs are broken — and patients are the ones paying the price.

In this episode of Boombostic Health, host Bradley Bostic sits down with Lathe Bigler of First Data Bank to unpack why e-prescribing hasn't evolved in decades, how opaque pricing keeps patients in the dark, and why the next wave of pharmacy network innovation could flip the power dynamic back to patients.

💡 What We Cover:

• Why patients are frustrated with rising prescription costs
• How transparency empowers patients with real choices
• What most people don't know about paying cash for prescriptions
• How e-prescribing networks can break pharmacy bottlenecks
• The role of technology in creating competition — and lowering costs
• This isn't just about convenience. It's about rebuilding trust in the healthcare system.

Chapters

00:00 Introduction to Boombostic Health and Conference Atmosphere

08:23 Innovations in e-Prescribing Networks

14:59 The Importance of Transparency and Choice in Healthcare

#boombostichealth #healthcareinnovation #PrescriptionTransparency #digitalhealth #patientempowerment #healthcaretechnology #prescriptioncosts #FirstDataBank #healthcaretechnology #healthcareleadership

Summary

This conversation explores the transformative potential of AI in healthcare, emphasizing the importance of agentic AI, interoperability, and the need for a shift in medical education. The speakers discuss the challenges and opportunities presented by AI technologies, the necessity of upskilling healthcare professionals, and the economic models that must evolve to support these changes. They highlight the importance of viewing information as an asset and the role of AI in enabling personalized, longitudinal care for patients.

Takeaways

• There's always a new challenge to overcome in healthcare.
• Mistakes often provide the best learning opportunities.
• Agentic AI is set to transform healthcare significantly.
• AI should enhance, not replace, human interaction in care.
• 80% of clinicians' time is spent on administrative tasks.
• Interoperability is crucial for effective patient care.
• AI can synthesize vast amounts of data for better outcomes.
• Investment in healthcare needs to focus on outcomes, not just costs.
• Medical education must evolve to prioritize preventive care.
• AI can turn healthcare from episodic to longitudinal care.

Chapters

00:00 The Knothole Metaphor: Personal Drive and Motivation 02:57 Transformational Technology: The Impact of Agentic AI 05:38 AI in Healthcare: Redefining Roles and Responsibilities 08:43 Interoperability: The Key to Better Clinical Care 11:50 AI Integration: Upskilling and Workflow Automation 14:39 AI Native Applications: The Future of Healthcare Technology 17:42 Longitudinal Care: The Role of AI in Patient Management 20:32 Investment in Healthcare: Shifting Economic Models 23:37 The Future of Medical Education: A New Paradigm 26:31 Conclusion: The Bright Future of AI in Healthcare

Summary

The business of healthcare is broken — but intelligence might finally fix it.

In this episode of Boombostic Health, Bradley Bostic and Jason Wenell reveal how to build an AI-ready healthcare system that learns, adapts, and delivers real value. Jason shares his three-layer framework — upskill people, automate workflows, and build AI-native systems that think.

Discover how AI is becoming the engine behind value-based care and what it means for the future of healthcare innovation.

Takeaways

• AI is revolutionizing healthcare and other industries.
• Value-based care relies heavily on data and predictive analytics.
• AI can help identify social determinants of health.
• Upskilling healthcare professionals is crucial for AI integration.
• AI native applications will define the future of healthcare technology.
• Data is considered the new oil in the healthcare sector.
• Personalized healthcare will improve patient outcomes significantly.
• AI should enhance human capabilities, not replace them.
• Ethical considerations in AI development are paramount.
• The future of healthcare is promising with the right AI applications.

Chapters

00:00 Introduction to AI in Healthcare 03:13 AI Applications in Value-Based Care 06:04 Navigating Change Management in Healthcare 09:00 The Shift to AI Native Applications 11:49 Data as the New Oil in Healthcare 15:00 Personalized Healthcare Through AI 18:05 Transitioning to AI Native Solutions 20:59 Ethical Considerations in AI Development 24:05 The Future of Human-Centric Healthcare

www.boombostichealth.com

https://linktr.ee/BradleyBostic

www.hc1.com

www.linkedin.com/in/bradleybostic

#boombostichealth #aihealthcare #healthcare #digitalhealth #healthcareinnovation #healthtech #valuebasedcare #ai

Summary

In this conversation, Craig Hittle discusses the evolving nature of telemedicine, emphasizing that it should not be viewed merely as a transactional service. Instead, he advocates for a model that fosters long-term relationships between patients and healthcare providers, enhancing the overall quality of care delivered through digital platforms.

Takeaways

• Telemedicine is often misunderstood as purely transactional.
• The goal of telemedicine should be to build relationships.
• Long-term relationships with providers can improve patient care.
• Telemedicine can enhance accessibility to healthcare services.
• Establishing trust is crucial in telehealth interactions.
• Patients should feel connected to their providers through telemedicine.
• Digital health platforms can facilitate ongoing care.
• The future of healthcare includes a blend of in-person and virtual visits.
• Effective communication is key in telehealth.
• Telemedicine can lead to better health outcomes when used correctly.

Chapters

00:00 Introduction to Health Tap and Primary Care Innovations 04:16 The State of Primary Care in America 05:08 The Rise of Telemedicine and Its Impact 09:30 Telemedicine: A Shift in Patient Care Dynamics 12:39 Understanding the Durbin Report and Its Implications 15:35 Chronic Condition Management and Telehealth 17:58 The Role of AI in Enhancing Patient Care 21:11 Genomic Information in Primary Care 24:16 The Future of Telemedicine and Patient Relationships 28:26 Challenges and Opportunities for Primary Care Doctors 34:08 Value-Based Care: Aligning Incentives for Better Health

Every year in the U.S., 275,000 people die because of medication mismanagement — a failure that drains $528 billion annually from our $5 trillion healthcare system. It's healthcare's deadly hidden failure.

That's where DecisionRx comes in. Their coined Medication Therapy Optimization (MTO) approach goes far beyond Pharmacogenetics (PGx), combining AI-powered insights with pharmacist-led care to stop the guesswork, lower risk, and deliver results at scale.

In this episode, host Bradley Bostic sits down with Mike Tilton, Chief Growth Officer at DecisionRx, to unpack the problem and spotlight the fix that's delivering:

• 8–10% reduction in total healthcare costs

• 94% patient satisfaction

• Maximum savings with minimal abrasion

"The $528B isn't in pill prices. It's in ER visits, hospital admissions, and complications that never had to happen." — Mike Tilton What You'll Learn

• Why $528B is being lost annually to preventable medication mismanagement.

• How DecisionRx's MTO model fixes the problem holistically — not just by swapping pills.

• Why ER visits, hospitalizations, and complications drive the real costs.

• Randall's story: from 18 prescriptions and $12K/month to a sustainable regimen that restored his health.

• How DecisionRx's shared-savings model makes adoption possible even for financially strapped health systems.

Medication mismanagement is killing us. DecisionRx has the fix. 👉 Learn more at decisionrx.com

Subscribe to Boombostic Health for bold conversations that expose healthcare's failures — and the solutions that can finally change it.