In this ASCO 2025 edition of VJOncology podcasts, we spotlight five game-changing studies set to reshape cancer care across multiple tumor types.

Join our host and a panel of leading oncology experts as they unpack the most impactful data from this year’s American Society of Clinical Oncology Annual Meeting. Discover pivotal insights from the MATTERHORN trial in gastric cancer, explore KRAS G12C-targeted combinations in NSCLC, and delve into resistance-prevention strategies in HR+/HER2– breast cancer with findings from the SERENA-6 trial. We also explore the potential of mRNA-based bispecific antibodies for solid tumors and analyze expanded results from CheckMate 8HW in MSI-high colorectal cancer.

With commentary from top investigators including Yelena Janjigian, Alexander Spira, Michael Gnant, Timothy Yap, and Heinz-Josef Lenz, this episode offers essential updates for oncology professionals. Tune in for a concise, expert-led review of the most practice-changing research from ASCO 2025.

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