In this week’s VJOncology podcast, we will be covering highlights from ASCO GU 2026 in San Francisco, CA. Dive into the latest advancements in genitourinary cancers, including groundbreaking trial results and emerging treatment strategies. In this episode, join Enrique Gallardo, MD, Parc Taulí University Hospital, Barcelona, Spain, Jan-Jaap Mellema, MD, Netherlands Cancer Institute, Amsterdam, The Netherlands, Pooja Ghatalia, MD, Fox Chase Cancer Center, Philadelphia, PA, Joaquim Bellmunt, MD, PhD, Dana-Farber Cancer Institute, Boston, MA, and, Aly-Khan Lalani, MD, McMaster University, Hamilton, Canada, as they discuss critical findings from ASCO GU 2026, including combination therapies, innovative approaches to bladder preservation, and novel biomarkers in prostate and renal cell carcinoma.

In this week’s VJOncology podcast, as part of Oesophageal Cancer Awareness Month in the UK, we are pleased to bring you the latest advances shaping the treatment landscape for oesophageal and gastroesophageal cancers. Join leading experts Yelena Janjigian, MD, Memorial Sloan Kettering Cancer Center, Berend van der Wilk, MD, Erasmus MC Cancer Institute, Kohei Shitara, MD, National Cancer Center Hospital East, and Ian Chau, MD, Royal Marsden Hospital, as they discuss pivotal data from key clinical trials across the disease spectrum. Our expert panel highlights how these data are refining first-line strategies, informing organ-preserving approaches, and advancing biomarker-driven therapies in oesophageal and gastroesophageal cancers.

In this week’s VJOncology podcast, we are delighted to bring you the latest advances in circulating tumor DNA (ctDNA)-informed monitoring and follow-up strategies in breast cancer. Join leading experts Wolfgang Janni, MD, University of Ulm, Ulm, Germany, Arielle Medford, MD, Massachusetts General Cancer Center, Boston, MA, Seth Wander, MD, PhD, Massachusetts General Hospital, Boston, MA, and Rinath Jeselsohn, MD, Dana-Farber Cancer Institute, Boston, MA, as they explore cutting-edge data from key studies including SURVIVE, LEADER, a Phase I/II trial of vepdegestrant, and PACE. Together, they discuss the evolving role of circulating tumor DNA in detecting molecular relapse, guiding early intervention strategies, monitoring treatment response, and predicting resistance across early and advanced ER+/HER2-negative and HR+/HER2-negative breast cancer settings.

In this week’s VJOncology podcast, we bring you key updates on the evolving landscape of checkpoint inhibition beyond PD-1 and PD-L1 across solid tumors. Join leading experts Jesus Fuentes-Antras, MD, NEXT Oncology Madrid, Madrid, Spain, Laurence Buisseret, MD, PhD, Institute Jules Bordet, Brussels, Belgium, and Yuxiang Ma, MD, PhD, Sun Yat-Sen University Cancer Center, Guangzhou, China, as they discuss novel bispecific and bifunctional immunotherapy strategies, first-in-human and early-phase clinical data, and emerging checkpoint inhibitor–ADC combinations shaping treatment paradigms in breast cancer, urothelial carcinoma, and other advanced malignancies.

In recognition of Cervical Cancer Awareness Month, this episode of VJOncology podcasts explores advances in cervical cancer prevention and treatment. We hear from three leading experts who discuss pivotal developments shaping clinical practice. Dr Domenica Lorusso from Fondazione IRCCS National Cancer Institute of Milan examines the breakthrough combination of immunotherapy and radiotherapy in locally advanced disease, highlighting practice-changing data from the KEYNOTE-A18 trial that established pembrolizumab plus chemoradiotherapy as the new standard of care for stage 3 cervical cancer. Dr Amanda Psyrri from National Kapodistrian University of Athens underscores the critical role of HPV vaccination in preventing not only cervical cancer but also HPV-associated oropharyngeal malignancies, particularly those caused by high-risk subtypes 16 and 18. Finally, Dr Alberto Farolfi from IRCCS Istituto Romagnolo per lo Studio dei Tumori shares real-world evidence on the addition of bevacizumab to pembrolizumab-chemotherapy regimens in advanced cervical cancer, demonstrating survival benefits without increased serious adverse events. This episode offers essential insights into the evolving landscape of cervical cancer management from prevention through advanced disease.

This podcast is available on the GI Cancer Channel on VJOncology, an independent medical education platform, which is supported by Takeda (Gold) and Gilead Sciences (Silver). Supporters have no influence over the production of content. The levels of sponsorship listed are reflective of the amount of funding given.

This VJOncology podcast explores the evolving landscape of immunotherapy in gastrointestinal malignancies, spanning from perioperative to adjuvant settings across multiple tumor types. Findings from the Phase II KEYSTEP-008 platform trial are presented, focusing on optimizing pembrolizumab-based combinations in MSI-high, mismatch repair deficient metastatic colorectal cancer. In addition, emerging biomarkers for immunotherapy beyond microsatellite instability in colorectal cancer are explored, including results from the TAPUR trial evaluating dual checkpoint inhibition in patients with BRCA1/2 alterations. The historically challenging adjuvant setting in hepatocellular carcinoma is examined through insights from the KEYNOTE-937 trial evaluating immunotherapy after curative-intent treatment. Finally, experts discuss the NEOSUMMIT-01 trial and how perioperative immunotherapy is transforming treatment strategies for locally advanced gastric and gastroesophageal junction cancers. Together, these perspectives highlight immunotherapy's expanding therapeutic potential across the GI cancer spectrum.

In this week’s VJOncology podcast, we bring you key developments in novel approaches in immunotherapy refractory head and neck cancer. Join head and neck cancer expert Amanda Psyrri, MD, PhD, FACP, National Kapodistrian University of Athens, Athens, Greece, as she discusses on mechanisms of resistance to checkpoint inhibitors, strategies to overcome resistance such as antibody drug conjugates (ADCs) and tumor vaccines, as well as the trials assessing anti-TIGIT inhibitors.

In this week’s VJOncology podcast, the first of 2026, we bring you key updates in the use of artificial intelligence (AI) in oncology and how it will impact clinicians and patients alike. Join renowned experts Anita Grigoriadis, PhD, King’s College London, London, UK, Rosalind Picard, ScD, MIT Media Lab, Cambridge, MA, Jana Lipkova, PhD, University of California, Irvine, CA, and Roberto Salgado, MD, PhD, Peter MacCallum Cancer Centre, Melbourne, Australia as they comment on how to increase AI literacy for oncologists, identifying patients with high-risk lobular breast cancer with AI, and more.

In this episode of the VJOncology Podcast, we bring you key highlights from the San Antonio Breast Cancer Symposium 2025 (SABCS 2025). This curated episode features expert insights into practice-changing data across HER2-positive metastatic disease, hormone receptor–positive early breast cancer, and the growing role of artificial intelligence in risk stratification. Leading investigators discuss advances in targeted therapies, endocrine treatment optimization, and AI-driven tools that may refine prognostic assessment and clinical decision-making in breast cancer.

In this week’s VJOncology podcast, we will be covering highlights from ESMO 2025 in Berlin, Germany. Gain expert insights in the field of genitourinary cancers, including highly-anticipated trial results, emerging biomarkers in kidney cancer, and the evolving role of radionuclides in  prostate cancer. Join renowned speakers Andrea Necchi, MD, IRCCS San Raffaele Hospital and Scientific Institute, Milan, Italy, Sara Coca Membribes, MD, Barts Health NHS Trust, London, UK, Scott Tagawa, MD, MS, FACP, Weill Cornell Medical Center, New York, NY, Paul Nguyen, MD, MBA, Dana-Farber Cancer Institute, Boston, MA, as they discuss trials such as GDFather-NEO, CALYPSO, and more.