Brian's podcast : Agentic Tomorrow

Production is getting cheap. Generation is getting cheap. The shelf is not. Alex and Jordan break down why distribution — the road to the customer — is the last durable moat in the AI era: the FTC's slotting-fee numbers, Buffett's 1993 letter naming Coca-Cola's distribution system as part of the moat, Morningstar's five sources that leave distribution off the list, Google's $26 billion payment for default placement and the 2024 ruling, why a channel can't be bought only accumulated (Sysco, Walmart), and the operator's audit: rented reach reprices, owned reach compounds. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

In the 1890s, factory owners swapped steam for electric motors and got nothing for a generation, because the payoff waited on redesigning the factory itself. Alex and Jordan teach the productivity J-curve: why AI's returns hide in intangible rebuilds the scoreboard cannot see, what the plant-level evidence says about the dip, and how operators budget for the valley. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

In 2014, Amazon taught a machine to grade résumés — and the machine learned to penalize the word "women's." Alex and Jordan trace how hiring became a two-sided ranking market built on AI talent discovery and algorithmic job matching, why a skill tag is not evidence, what the bias studies actually found, and why the money now pools in audits, verification, and proof of work nobody can fake. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

A quarter of a trillion dollars, and most of the people building it are broke. Goldman Sachs puts the creator economy near two hundred fifty billion dollars today, on its way to nearly five hundred billion by twenty twenty-seven — yet more than half of creators earn under fifteen thousand dollars a year. Alex and Jordan trace version one, from YouTube's Partner Program to Patreon, and the version-two rebuild: AI agents as staff, a diversified revenue stack, and tokenized capital that turns the audience into a cap table. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

In 1987, trading software could only obey — and helped sell the market down 22.6% in a day. Today's trading agents hold goals: they read filings, debate through committees of specialists, and learn from losses. Alex and Jordan trace the road from portfolio insurance to multi-agent trading desks, the fine print in the research, and why the edge moved from prediction to data, infrastructure, and accountable risk. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

Aging was fate for four thousand years. Now it is a funded engineering program: a record $18.4 billion of longevity investment in 2025, brain implants moving cursors by thought, cells reprogrammed younger in the lab. Alex and Jordan walk through the prototypes, the escape-velocity math that breaks retirement planning, the honest skeptic case, and where the money pools. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

Medvi, a two-person company built with a dozen AI tools, is on track for 1.8 billion dollars in sales this year, and Sam Altman's betting pool says a one-person billion-dollar company is coming. Alex and Jordan break down the leaderboard: Base44's 80 million dollar sale to Wix and its sprint past 100 million in annual revenue, Pieter Levels' solo 3 million dollar portfolio, and Midjourney's 500 million with forty people, plus the honest skeptic case and the three-move playbook for founders who want to be on it. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

AI can make a company faster and cheaper while quietly deleting the reason its customers pay. Alex and Jordan break down AI and business model obsolescence: Getty and Shutterstock's pivot from selling pictures to licensing data, the task-level evidence from Brynjolfsson, BCG and GitHub, the four-step sequence by which a business model dies, the honest skeptic numbers (Uber's four agent-booked rides out of 320 million), and the three moves operators can make — split revenue by task vs position, reprice around judgment and accountability, and sell to the customer's own AI agent. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

Gartner says AI agents will outnumber human sellers ten to one by 2028, yet fewer than 40% of sellers expect agents to improve their productivity. Alex and Jordan break down where AI agents win — volume, speed, follow-up, and research — and where humans still close at roughly twice the rate, with Anthropic's Project Deal experiment, Gartner's buyer survey, and the solo-founder playbook for blending both. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH

Gartner predicts more than 40% of agentic AI projects will be cancelled by the end of 2027, and MIT found 95% of generative AI pilots deliver no measurable profit-and-loss impact. Alex and Jordan break down the five mistakes that kill most AI agents — the learning gap, agent washing, runaway unit costs, governance as an afterthought, and automating the flashy job instead of the valuable one — plus the survivor playbook the 5% use: one pain point, real data, real cost per task, and engineering for production from day one. For founders and solo founders, the message is simple: the 60% that ship are not smarter, just more disciplined. From Brian Fernando Nuesi's Agentic Tomorrow. Book: https://www.amazon.com/dp/B0GW5CSHK6 — Newsletter: https://briannuesi.substack.com — Podcast: https://open.spotify.com/show/3PcECfoWuocMOUpIxyGJKH