Dr John Frater talks about his research into finding a cure for HIV. It is increasingly apparent that highly active antiretroviral therapy (HAART) may not be the long-term solution to the management of HIV infection, and that other avenues need to be explored. As a result of various recent cases, the idea of eradicating HIV altogether is becoming less unimaginable to some scientists. Dr John Frater's work focuses on quantification of viral reservoirs, sequence analysis, immunology, as well as fundamental research into new approaches for the eradication of HIV.