Viremic – Cases in HIV

Case 11. Unfolding Stories to Untangle Syphilis Testing


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A 32-year-old man with well-controlled HIV, seen after a recent relationship split and sexual activity with new partners, is screened and diagnosed with syphilis. Eileen discusses this case with guest Dr. Matthew Hamill, who reviews his approach to STI screening and risk reduction, emphasizing an approach that normalizes screening. Matthew then reviews syphilis testing, diagnosis, and staging, including neurosyphilis assessment, and treatment.

Related Guidelines and Guidance

Centers for Disease Control and Prevention:

  • Sexually Transmitted Infections Treatment Guidelines, 2021. Screening Recommendations and Considerations Referenced in Treatment Guidelines and Original Sources.

NYSDOH AI Clinical Guidelines Program: 

  • Guidance: Adopting a Patient-Centered Approach to Sexual Health
  • GOALS Framework for Sexual History Taking in Primary Care


Clinical Resources

  • National STD Curriculum: A free educational website from the University of Washington STD Prevention Training Center.
  • STD Clinical Consultation Network: From the National Network of STD Clinical Prevention Training Centers 
  • For New York State Clinicians: CEI Clinician Consultation Phone Line: 866-637-2342: A toll-free service for New York State clinicians offering real-time clinical consultations with specialists on HIV, sexual health, hepatitis C, and drug user health.
  • CEI Sexual Health Resources web page: https://ceitraining.org/resources/sexual-health


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Viremic – Cases in HIVBy Dr. Eileen Scully & Dr. Christopher Hoffmann