Multiple studies highlight the benefits of direct oral anticoagulants (DOACS) with lower incidence of side effects and non-inferiority to warfarin. Join host, Geoff Wall, and guest, Mathew Boyd, as they discuss the FRAILE AF study and whether warfarin may be the best bet in older adults.
 
The GameChanger:
DOACs are recommended by nearly all relevant major medical guidelines as the anticoagulant of choice in atrial fibrillation. A new study has found that in frail elderly patients, warfarin may be associated with fewer bleeding episodes.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

Guest
Mathew Boyd, PharmD
Clinical Pharmacist
Unity Point

Reference
Joosten LPT, van Doorn S, van de Ven PM,et al. Safety of Switching from a Vitamin K Antagonist to a Non-Vitamin K Antagonist Oral Anticoagulant in Frail Older Patients with Atrial Fibrillation: Results of the FRAIL-AF Randomized Controlled Trial. Circulation. 2023 Aug 27. doi: 10.1161/CIRCULATIONAHA.123.066485. Epub ahead of print. PMID: 37634130.

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.123.066485

Pharmacist Members, REDEEM YOUR CPE HERE!
 
Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)


CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe the design and results of the FRAIL AF study
2. Apply the results of the Groningen Frailty Index to a specific patient

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-302-H01-P
Initial release date: 9/25/2023
Expiration date: 9/25/2024
Additional CPE details can be found here.

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In this week's Level Up episode Ashlee speaks with CoraLynn Trewet who has the honor of being the first recipient of the Thomas R. Temple Mentorship Award from the Iowa Pharmacist Association.  A testament to the transformative power of mentorship, CoraLynn’s journey is one of reciprocation, authenticity, and the profound impact of being truly seen. Join us as we traverse her inspiring journey and unlock insights into the essence of a meaningful mentorship. 

CoraLynn emphasizes the importance of openness to receiving mentorship and the ripple effect of paying it forward. We also shed light on the undeniably joyous pride that blooms from a mentee's success, and the invaluable role of having varied mentors at different junctures of our careers. This episode promises a refreshing view on mentorship, highlighting the significance of forging connections with individuals who ignite our inspiration.

Later in the episode, CoraLynn shares her wisdom on the art of building authentic relationships. We dive into the subtleties of trust, authenticity, and vulnerability, and their pivotal role in fostering meaningful relationships. CoraLynn also gives valuable tips on being an exceptional mentor, from being an attentive listener to inspiring others to find answers within themselves. We wrap up with a discussion on the importance of making others feel seen and cherished, a sentiment that beautifully encapsulates CoraLynn's own mentorship journey. 

Join us for this enriching conversation on the transformative power of meaningful mentorship.

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Although uncommon, severe headaches, neck sitffness, and other symptoms may occur after epidural procedures (lumbar puncture). Join host, Geoff Wall, as he evaluates new guidelines for the management of these symptoms
 
The GameChanger
Post procedural headache can be severe and last up to two weeks or longer. Management includes standard pain medications but may require caffeine or application of a blood patch to prevent dural leak.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
 
Reference
Uppal V, Russell R, Sondekoppam R, et al. Consensus Practice Guidelines on Postdural Puncture Headache From a Multisociety, International Working Group: A Summary Report. JAMA Netw Open. 2023;6(8):e2325387. doi:10.1001/jamanetworkopen.2023.25387

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808365

Pharmacist Members, REDEEM YOUR CPE HERE!
 
Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)


CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss with patients the risk factors and symptoms of post-procedural headache
2. Discuss pain management strategies for post-procedural headache

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-301-H01-P
Initial release date: 9/18/2023
Expiration date: 9/18/2024
Additional CPE details can be found here.

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Drawing upon personal experiences and professional acumen, our guest Dawn Grittman, a steadfast advocate for mental health awareness and suicide prevention, joins Ashlee to peel back the layers of her journey intertwined with the National Alliance on Mental Illness (NAMI). As a pharmacist, Dawn’s story is a compelling narrative of transition from volunteering with NAMI to becoming a full-time crusader, keen on enlightening both healthcare providers and the general public on mental health issues. Expect an introspective look into her pioneering programs and the consequential role of candid discussions about mental health and suicide.

Navigating the labyrinth of suicide prevention, especially from a pharmacist's perspective, often encompasses a series of complexities. With an empathetic and expert approach, Dawn guides us through the nuanced process of recognizing cues and initiating life-saving conversations. Highlighting the imperative need for evidence-based resources and situational awareness, she brings to light the often overlooked role of the American Foundation for Suicide Prevention and NAMI’s Provider Program in equipping health professionals with vital knowledge about mental health conditions.

With a persistent focus on the role of pharmacists in suicide prevention, Dawn underscores the indispensable power of building patient relationships. Her passion is infectious as she emphasizes the wealth of available resources and the potential of pharmacists to provide critical help. Covering the deeply affecting personal impacts of suicide and its alarming statistics, she inspires a shift from despair to action. Dawn's poignant journey and incisive insights underscore our shared responsibility in fostering mental health awareness and suicide prevention. Her story serves as a compelling call to action to each one of us.

References:
NIMH
SAMHSA SAFE-T
QPR

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N-Acetyl Cystine (NAC) has been long used as the antidose for acetaminophen poisonings - although with variable implementation. Join host, Geoff Wall, and guest, Kayla Myers, discuss a new consensus guideline for appropriate treatment of acetaminophen overdose.
 
The GameChanger
NAC should be used if any doubt of acetaminophen poisoning based on new consensus guidelines. NAC may be used continued beyond standard dosing for chronic or high amounts of acetaminophen.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

Guest
Kayla Myers, PharmD
Clinical Pharmacist
Unity Point

Reference
Dart RC, Mullins ME, Matoushek T, et al. Management of Acetaminophen Poisoning in the US and Canada: A Consensus Statement. JAMA Netw Open. 2023;6(8):e2327739. doi:10.1001/jamanetworkopen.2023.27739

https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2808062

Pharmacist Members, REDEEM YOUR CPE HERE!
 
Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)


CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Apply the new modified Rumack-Matthew nomogram to a potential acetaminophen poisoning
2. Discuss the use of fomepizole in the use of acetaminophen overdose

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-300-H01-P
Initial release date: 9/11/2023
Expiration date: 9/11/2024
Additional CPE details can be found here.

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Curious about the pivotal role pharmacists play in mental health care? Tune into Level Up host Ashlee Klevens-Hayes' enlightening conversation with Amy Werremeyer, a board-certified psychiatric pharmacist, tenured professor & chair of pharmacy practice at North Dakota State University, and tireless advocate for people with mental health and substance use disorders. Hear about her inspiring leap from inpatient psychiatry to her current role in a community mental health center, where she is dedicated to not only prescribing but educating patients about their medications and providing realistic expectations and coping tools.

The second half of our chat dives into the rising demand for specialty pharmacists in the mental health sector and the opportunities that arise with this shift. Amy enlightens us about the potential of improved medication management and non-pharmacological therapies. Her extensive knowledge and passion make her insights on the future of pharmacy in mental health invaluable. From creating access to improving the quality of care, this episode promises to deliver resources, tips, and personal anecdotes that can educate and inspire. Don't miss out on this exploration of mental health in pharmacy with Amy.

To learn more about our Pharmacist by Design membership, click here.

For more info on our upcoming live course 'Illuminating the Darkness: Depression Guideline Update', visit ceimpact.com.

References:
2023 ASHP Forecast
Shatterproof
American Association of Psychiatric Pharmacists

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The American Heart Association updated the Coronary Artery Disease (CAD) guidelines for the first time in a decade. Join host, Geoff Wall, as he evaluates what's new in CAD pharmacotherapy.
 
The GameChanger
CAD pharmacotherapy is dependent on aggressive lipid management whereas antiplatelet and beta-blocker therapy is now more nuanced.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

Reference
Virani SS, Newby LK, Arnold SV, et al. 2023 AHA/ACC/ACCP/ASPC/NLA/PCNA Guideline for the Management of Patients With Chronic Coronary Disease: A Report of the American Heart Association/American College of Cardiology Joint Committee on Clinical Practice Guidelines. Circulation. 2023 Jul 20. doi: 10.1161/CIR.0000000000001168. Epub ahead of print. PMID: 37471501.

https://www.ahajournals.org/doi/epdf/10.1161/CIR.0000000000001168

Pharmacist Members, REDEEM YOUR CPE HERE!
 
Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)


CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Discuss the new AHA coronary artery disease (CAD) guidelines
2. Apply AHA CAD guidelines for medical management of a patient with stable CAD

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-295-H01-P
Initial release date: 9/4/2023
Expiration date: 9/4/2024
Additional CPE details can be found here.

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Episode ten of the Level Up podcast features host Ashlee Klevens Hayes and guest Hashim Zaibak CEO at Hayat Pharmacy. 

Zaibek started Hayat Pharmacy in 2011, a locally owned pharmacy that has since expanded to 20 locations across the greater Milwaukee area. 

In this episode, we discuss pharmacy-based hearing aids and how they can play a role in expanding your services as a pharmacy. Zaibak joins to discuss the benefits Hayat Pharmacy has found as a result of providing OTC hearing aids, the keys to his company's expansion & success, and how pharmacists can swiftly incorporate OTC hearing aids into their own private pharmacy.

To contact Hashim Zaibek, email [email protected]. 

To learn more about our Pharmacist by Design membership, click here.

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Narcolepsy can exact a devastating toll on the (probably underdiagnosed) patient. Treatment can range from lifestyle to medications. Join host, Geoff Wall, as he explores a new oral orexin agonist for the treatment of narcolepsy.
 
The GameChanger
Narcolepsy is more common than assumed. Current treatments include stimulant agents but a new class of orexin agonists may be effective, yet have safety concerns.
 
Host
Geoff Wall, PharmD, BCPS, FCCP, BCGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health
 
Reference
Dauvilliers Y, Mignot E, Del Río Villegas R, et al. Oral Orexin Receptor 2 Agonist in Narcolepsy Type 1. N Engl J Med. 2023 Jul 27;389(4):309-321. doi: 10.1056/NEJMoa2301940. PMID: 37494485.

https://www.nejm.org/doi/full/10.1056/NEJMoa2301940?query=featured_home

Pharmacist Members, REDEEM YOUR CPE HERE!
 
Not a member? Get a Pharmacist Membership & earn CE for GameChangers Podcast episodes! (30 mins/episode)


CPE Information
 
Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Describe the manifestations, prevalence, and types of narcolepsy and associated symptoms.
2. Discuss the benefits and risks of orexin drugs in treatment of narcolepsy.

0.05 CEU/0.5 Hr
UAN: 0107-0000-23-292-H01-P
Initial release date: 8/28/2023
Expiration date: 8/28/2024
Additional CPE details can be found here.

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Episode ten of the Level Up podcast features host Ashlee Klevens Hayes and guest Elizabeth Skoy.  

In this episode, we discuss how your pharmacy can expand its services. Elizabeth joins to discuss her career, and the Center for Collaboration and Advancement in pharmacy.

To learn more about our Pharmacist by Design membership, click here. 

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