CGT Square Talk

Part 2 of our AI series dives deeper into what’s actually powering agentic AI systems, the models behind the scenes.

In this episode, the team breaks down how different models are used across AI agents, why a model strategy is critical, and how cost, performance, and reliability all play into real-world implementations.

We also explore:

Why using a single model isn’t scalable
How fallback models prevent downtime
The real cost of APIs vs subscriptions
Why human-in-the-loop is still essential
And a major AI-driven security breach that highlights new risks companies face

Whether you're building with AI or just trying to understand how these systems actually work in production, this episode gives you a grounded, behind-the-scenes look.

Stay tuned for Part 3, where we’ll walk through a live demo and share practical tips & workflows.

00:00 – Intro & Recap of Part 1  
00:54 – What AI Models Actually Do (The “Brains”)  
02:01 – Why Model Strategy Matters  
03:30 – Cost Considerations & Token Limits  
05:02 – Primary vs Fallback Models Explained  
07:30 – Real Issues Switching Between Models  
09:44 – Trial & Error: Choosing the Right Model  
10:38 – When AI Gets It Wrong (Fake Sources Example)  
11:27 – Matching Models to Tasks (Research vs Coding)  
12:50 – Human-in-the-Loop: Why It’s Critical  
15:07 – AI in Development: Junior vs Senior Engineers  
16:47 – Where AI Fits in the SDLC  
18:48 – AI as a Tool, Not a Replacement  
20:32 – Strategy Before Implementation  
21:06 – Real Model Stack (What They Actually Use)  
23:49 – Subscription vs API Cost Breakdown  
26:01 – Real Example: $100 API Cost in One Day  
27:30 – Cheaper Model Alternatives (AWS, Open Models)  
28:54 – The Future of AI Cost Optimization  
32:54 – Enterprise vs Open Source Models  
34:33 – Compute Power & Infrastructure Realities  
35:59 – Why Design Matters Before Building AI  
37:39 – From Experimentation to Architecture  
40:20 – The “Skunkworks” Approach to AI  
41:40 – Major AI Security Risks (Real Breach Case)  
42:37 – How AI Can Exploit APIs  
44:25 – Why This Security Threat Matters  
46:55 – Is Software Security Falling Behind?  
49:59 – Why Traditional Pen Testing Isn’t Enough  
51:19 – AI vs Human Security Testing  
52:51 – What’s Coming in Part 3 (Demo + Tips)

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

AI isn’t just a buzzword anymore; it’s actively reshaping how software gets built.

In this episode of CGT Square Talk, we sit down with Kenny Gibbons to break down how we used agentic AI to automate parts of the software development lifecycle and actually built a working feature in just a few hours.

From security concerns and “blast radius” thinking to real-world implementation inside a regulated pharma environment, this is a candid look at what AI can (and can’t) do today.

💡 In Part 1, we cover:

What agentic AI actually is (and why it matters)
The risks of open-source AI tools
How we set up guardrails and “mission control.”
Training AI agents to understand real systems
The future of AI in regulated industries

👉 In Part 2, we go deeper into scaling this approach and what it means for the future of work.

00:00 – Intro & Why AI Is Back on the Agenda
00:46 – Meet the Team & Backgrounds
02:17 – What Is Clawbot / OpenClaw?
03:10 – Armin’s Technical Background & Journey
04:32 – Why Agentic AI Is a Big Deal
06:35 – Security Risks: “Anyone Can Download This”
07:35 – Guardrails & Controlling the “Blast Radius”
10:08 – What Is Agentic AI (Explained Simply)
12:25 – Balancing Innovation vs. Control
13:43 – Setting Up the System (VPS + Security)
15:35 – Building “Mission Control” for AI Agents
19:12 – Why Architecture Matters More Than Just Spinning Up Agents
23:07 – Where AI Fits in the Software Development Lifecycle
26:20 – Hybrid Agile + Compliance (Pharma Reality)
30:03 – Deciding What Should (and Shouldn’t) Be Automated
31:48 – Training the AI Agents
34:21 – Teaching AI Compliance (CFR 21 Part 11)
36:56 – The Power of Autonomous Learning
39:09 – Will AI Change Regulation?
41:06 – The Future: AI in the FDA & Compliance
45:16 – How We Trained the Developer Agent
47:32 – Building the Full AI Workflow
49:08 – Human Checkpoints & Safeguards
51:41 – Running the First Real Test
53:07 – Building a Feature in 3 Hours
54:16 – AI Finding Its Own Bugs (and Yours)
57:25 – Risks, Hallucinations & Control
1:00:01 – Building Internal Tools with AI
1:04:18 – Will AI Replace SaaS?
1:07:24 – The Risks of Democratizing Software
1:10:05 – Final Advice: Don’t Take the Leash Off Yet

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

In this episode, we explore key system considerations in Cell & Gene Therapy with Christian Fuchs, Head of Orchestration and Exceptions Management for Cell & Gene Therapy. Christian brings deep global expertise to the conversation and is responsible for building and leading the operational business capabilities that support the “virtual treatment journey”—orchestrating the data, transactions, and documents that enable CGT delivery in both clinical and commercial settings.

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

Welcome back for part 2! This week dive back into the Enneagram with our guest and Certified Integral Coach Cyrus Tosun Emotional Intelligence is the key to successful collaboration. Cyrus, with over 10 years experience in coaching and leadership development, gets the team to explore successful ways of working with different personality types and share some of their own stories. Cyrus with his calm style has a knack for helping people unlock their true potential and create thriving, meaningful careers. He’s also a Faculty member at New Ventures West, where he mentors future coaches and offers expertise in executive coaching. 
Join us on this interesting ride and see how you can apply the Enneagram and Cyrus’ approach to successful collaboration in a dynamic environment like CGT.

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

This week join the BlueSquared team as they delve into their Enneagram
personalities with our guest and Certified Integral Coach Cyrus Tosun Emotional Intelligence is the key to successful collaboration. Cyrus, with over 10 years experience in coaching and leadership development, gets the team to explore successful ways of working with different personality types and share some of their own stories. Cyrus with his calm style has a knack for helping people unlock their true potential and create thriving, meaningful careers. He’s also a Faculty member at New Ventures West, where he mentors future coaches and offers expertise in executive coaching. 
Join us on this interesting ride and see how you can apply the Enneagram and Cyrus’ approach to successful collaboration in a dynamic environment like CGT.

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

In this episode of CGT Square Talk, the BlueSquared team—Anthony, Ian, Gary, and Armen—delve into the critical role of collaboration in the Cell and Gene Therapy space. Focusing on the systems and processes that drive success, they explore how teamwork enhances operational efficiency and accelerates innovation. From streamlining workflows to optimizing cross-functional efforts, collaboration is key to unlocking new possibilities. Join us as we discuss practical approaches to building stronger partnerships and fostering collaboration that can transform the industry.

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

In today’s episode, we are excited to welcome Julia Zats, a senior IT executive with over 25 years of experience managing and enabling high-performance teams. With deep expertise in developing global IT strategies and implementing systems that support commercialization, Julia has been instrumental in driving success across the cell and gene therapy space. She shares her insights on the importance of collaboration in clearing roadblocks and enabling teams to thrive in this rapidly evolving industry. We also explore how tools like the Enneagram system for personality types can enhance team dynamics, streamline communication, and make teams work more effectively together. Join us for an engaging conversation on fostering collaboration and maximizing team potential in a highly specialized field.

Enneagram Link: https://www.enneagraminstitute.com/
David and Goliath by Malcom Gladwell: https://www.amazon.com/David-Goliath-Underdogs-Misfits-Battling/dp/0316204374

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

Today, we’re sitting down with our BlueSquared team to recap our time at the LSX Conference in Boston. From startup funding and patient access to collaboration and AI, we’ll dive into the key takeaways shaping the future of healthcare. Let’s get into it!

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

Cooperation, simplification and accepting the CGT paradigm shift are all on the table as we explore these topics with our guest this week, Sanjay Srivastava. Sanjay is well known for his thoughtful and insightful approach to problem solving. Now a senior management consultant with over 20 years of experience in the life sciences and healthcare sectors, Sanjay started this journey as an academic with a PhD in Biochemistry. All this expertise gives him a leg up in defining and implementing new capabilities for therapy development, manufacturing, and commercialization. Welcome Sanjay!

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!

Join us and our guest Jena McCredie this week for a super insightful conversation on everything from supply chain strategy and planning to teams and org structures that can better align teams with success. Jena, in her over twenty years of experience in the pharmaceutical and biotechnology space, knows well the challenges in product management, strategy development and operations, especially within innovative sectors like cell and gene therapy. Her roles have spanned from technical operations and product management to commercial operations and systems analysis. Welcome Jena!

CGT Square Talk
Hosted by: Anthony Roth & Armen Gasanyan 

New episodes every other Monday!